1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Y	F	V	G	V	D	L	A	W	A	G	R	N	P	T	G	V	A	A	V	D	A	D	G	C	L	V	G	V	G	A	A	R	D	D	A	S	V	L	A	A	L	R	P	Y	V	V	G	D	C	L	V	A	F	D	A	P	L	V
Secondary structure
SS confidence
Disorder		?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	N	R	T	G	Q	R	P	A	E	A	A	L	N	R	D	F	R	Q	F	E	A	G	A	Y	P	A	N	T	E	K	P	E	F	A	D	V	P	R	A	A	R	L	A	R	Q	L	A	L	D	M	D	P	L	S	S	A	T	R
Secondary structure
SS confidence
Disorder			?	?	?	?													?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?														?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	A	I	E	V	Y	P	H	P	A	T	V	A	L	F	R	L	P	R	A	L	K	Y	K	A	K	P	G	R	S	V	D	L	L	K	S	E	L	L	R	L	M	D	G	V	E	G	L	A	Q	A	G	V	R	M	Q	V	A	G	Q
Secondary structure
SS confidence
Disorder																		?		?	?	?		?	?	?	?	?	?	?	?	?	?	?	?															?	?	?	?			?	?		?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	D	W	V	S	L	R	R	Q	V	T	V	A	Q	R	K	S	D	L	R	A	A	E	D	P	I	D	A	V	V	C	A	Y	V	A	L	Y	A	Q	R	R	P	A	D	V	T	I	Y	G	D	F	T	T	G	Y	I	V	T	P	S
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Sequence		L	P	T	D	F	R	T	A	P	D	A	G	R	R	A	R	A	R	R
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 35%) Alpha helix ( 39%) Beta strand ( 15%)

Rank Aligned region

PDB 4ep5 chain A Region: 1 - 227 Aligned: 138 Modelled: 143 Confidence: 96.2% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:crossover junction endodeoxyribonuclease ruvc; PDBTitle: thermus thermophilus ruvc structure Phyre2 PDB 4eht chain A Region: 1 - 35 Aligned: 32 Modelled: 35 Confidence: 89.3% Identity: 16% PDB header:electron transport Chain: A: PDB Molecule:activator of 2-hydroxyisocaproyl-coa dehydratase; PDBTitle: activator of the 2-hydroxyisocaproyl-coa dehydratase from clostridium2 difficile with bound adp Phyre2 PDB 1hux chain A Region: 1 - 29 Aligned: 26 Modelled: 29 Confidence: 87.9% Identity: 15% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: BadF/BadG/BcrA/BcrD-like Phyre2 PDB 1vhx chain A Region: 1 - 55 Aligned: 52 Modelled: 55 Confidence: 85.1% Identity: 23% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Putative Holliday junction resolvase RuvX Phyre2 PDB 3bzk chain A domain 5 Region: 2 - 78 Aligned: 69 Modelled: 71 Confidence: 84.6% Identity: 26% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Tex RuvX-like domain-like Phyre2 PDB 1iv0 chain A Region: 1 - 68 Aligned: 64 Modelled: 68 Confidence: 83.5% Identity: 17% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Putative Holliday junction resolvase RuvX Phyre2 PDB 5nck chain A Region: 1 - 28 Aligned: 25 Modelled: 28 Confidence: 73.7% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:n-acetylmannosamine kinase; PDBTitle: the crystal structure of n-acetylmannosamine kinase in fusobacterium2 nucleatum Phyre2 PDB 2e2p chain A Region: 1 - 35 Aligned: 32 Modelled: 35 Confidence: 73.6% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:hexokinase; PDBTitle: crystal structure of sulfolobus tokodaii hexokinase in2 complex with adp Phyre2 PDB 3eo3 chain B Region: 1 - 46 Aligned: 43 Modelled: 46 Confidence: 62.4% Identity: 21% PDB header:isomerase, transferase Chain: B: PDB Molecule:bifunctional udp-n-acetylglucosamine 2-epimerase/n- PDBTitle: crystal structure of the n-acetylmannosamine kinase domain of human2 gne protein Phyre2 PDB 2aa4 chain A domain 1 Region: 1 - 67 Aligned: 64 Modelled: 67 Confidence: 61.5% Identity: 16% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: ROK Phyre2 PDB 3vew chain A Region: 1 - 29 Aligned: 28 Modelled: 29 Confidence: 58.4% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:o-carbamoyltransferase tobz; PDBTitle: crystal structure of the o-carbamoyltransferase tobz in complex with2 adp Phyre2 PDB 2aa4 chain B Region: 1 - 67 Aligned: 64 Modelled: 67 Confidence: 58.0% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:putative n-acetylmannosamine kinase; PDBTitle: crystal structure of escherichia coli putative n-2 acetylmannosamine kinase, new york structural genomics3 consortium Phyre2 PDB 2ivo chain C Region: 1 - 29 Aligned: 25 Modelled: 29 Confidence: 54.2% Identity: 16% PDB header:hydrolase Chain: C: PDB Molecule:up1; PDBTitle: structure of up1 protein Phyre2 PDB 3zeu chain E Region: 1 - 32 Aligned: 29 Modelled: 32 Confidence: 54.0% Identity: 24% PDB header:hydrolase Chain: E: PDB Molecule:probable trna threonylcarbamoyladenosine biosynthesis PDBTitle: structure of a salmonella typhimurium ygjd-yeaz heterodimer bound to2 atpgammas Phyre2 PDB 6fpe chain G Region: 1 - 34 Aligned: 31 Modelled: 34 Confidence: 51.8% Identity: 23% PDB header:rna binding protein Chain: G: PDB Molecule:trna n6-adenosine threonylcarbamoyltransferase; PDBTitle: bacterial protein complex Phyre2 PDB 1zc6 chain A Region: 1 - 35 Aligned: 32 Modelled: 33 Confidence: 47.0% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:probable n-acetylglucosamine kinase; PDBTitle: crystal structure of putative n-acetylglucosamine kinase from2 chromobacterium violaceum. northeast structural genomics target3 cvr23. Phyre2 PDB 2ch5 chain A domain 2 Region: 2 - 32 Aligned: 28 Modelled: 31 Confidence: 45.6% Identity: 25% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: BadF/BadG/BcrA/BcrD-like Phyre2 PDB 3eno chain B Region: 1 - 28 Aligned: 24 Modelled: 27 Confidence: 43.7% Identity: 13% PDB header:hydrolase/unknown function Chain: B: PDB Molecule:putative o-sialoglycoprotein endopeptidase; PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1 Phyre2 PDB 3hz6 chain A Region: 1 - 32 Aligned: 29 Modelled: 32 Confidence: 42.2% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:xylulokinase; PDBTitle: crystal structure of xylulokinase from chromobacterium violaceum Phyre2 PDB 1hjr chain A Region: 3 - 224 Aligned: 143 Modelled: 156 Confidence: 42.0% Identity: 22% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: RuvC resolvase Phyre2 1 c4ep5A_ 2 c4ehtA_ 3 d1huxa_ 4 d1vhxa_ 5 d3bzka5 6 d1iv0a_ 7 c5nckA_ 8 c2e2pA_ 9 c3eo3B_ 10 d2aa4a1 11 c3vewA_ 12 c2aa4B_ 13 c2ivoC_ 14 c3zeuE_ 15 c6fpeG_ 16 c1zc6A_ 17 d2ch5a2 18 c3enoB_ 19 c3hz6A_ 20 d1hjra_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61