1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	S	R	F	L	P	Y	A	T	T	P	G	R	L	L	A	Q	L	I	S	D	I	T	V	A	V	W	T	T	L	W	M	L	V	G	L	A	V	H	D	A	I	S	I	I	G	E	A	G	R	Q	I	E	I	G	S	H	G	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?		?																																								?			?				?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	G	N	L	A	A	A	G	Q	D	A	Q	R	I	P	V	V	G	D	A	L	S	N	P	I	T	A	A	S	Q	A	A	L	D	I	A	G	A	G	H	N	L	D	T	T	A	G	W	L	A	V	V	L	A	L	A	V	A	A	T
Secondary structure
SS confidence
Disorder							?	?	?	?		?	?														?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	I	L	A	V	A	M	P	W	L	F	L	R	L	R	F	C	R	R	K	W	T	V	T	T	L	A	A	T	P	A	G	R	Q	L	L	A	L	R	A	L	A	N	R	P	P	G	K	L	A	A	V	S	T	D	P	V	G	A	W
Secondary structure
SS confidence
Disorder																													?														?	?	?	?						?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.
Sequence		R	R	E	D	P	A	T	M	R	A	L	A	A	L	E	L	R	A	A	G	I	P	L	R	G	D
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 23%) Alpha helix ( 81%) Beta strand ( 0%) TM helix ( 25%) (View membrane topology prediction)

Rank Aligned region

PDB 4wpy chain A Region: 72 - 105 Aligned: 34 Modelled: 34 Confidence: 28.3% Identity: 18% PDB header:de novo protein Chain: A: PDB Molecule:protein dl-rv1738; PDBTitle: racemic crystal structure of rv1738 from mycobacterium tuberculosis2 (form-ii) Phyre2 PDB 1gr0 chain A domain 1 Region: 73 - 88 Aligned: 16 Modelled: 16 Confidence: 27.0% Identity: 44% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 2fgg chain A domain 1 Region: 73 - 105 Aligned: 33 Modelled: 33 Confidence: 26.3% Identity: 15% Fold: dsRBD-like Superfamily: Rv2632c-like Family: Rv2632c-like Phyre2 PDB 5ydc chain A Region: 172 - 204 Aligned: 31 Modelled: 33 Confidence: 23.8% Identity: 19% PDB header:transcription regulator Chain: A: PDB Molecule:uncharacterized hth-type transcriptional regulator rv1828; PDBTitle: crystal structure of mercury soaked c-terminal domain of rv1828 from2 mycobacterium tuberculosis Phyre2 PDB 2axt chain M domain 1 Region: 106 - 130 Aligned: 25 Modelled: 25 Confidence: 17.4% Identity: 8% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein M, PsbM Family: PsbM-like Phyre2 PDB 3a0h chain M Region: 106 - 130 Aligned: 25 Modelled: 25 Confidence: 14.3% Identity: 8% PDB header:electron transport Chain: M: PDB Molecule:photosystem ii reaction center protein m; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 1q90 chain B Region: 26 - 130 Aligned: 86 Modelled: 92 Confidence: 11.8% Identity: 20% Fold: Heme-binding four-helical bundle Superfamily: Transmembrane di-heme cytochromes Family: Cytochrome b of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Phyre2 PDB 2l35 chain B Region: 8 - 35 Aligned: 28 Modelled: 28 Confidence: 11.2% Identity: 21% PDB header:protein binding Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer Phyre2 PDB 2l34 chain B Region: 8 - 35 Aligned: 28 Modelled: 28 Confidence: 11.0% Identity: 21% PDB header:protein binding Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12 transmembrane homodimer Phyre2 PDB 4wol chain A Region: 8 - 35 Aligned: 28 Modelled: 28 Confidence: 11.0% Identity: 21% PDB header:signaling protein Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: crystal structure of the dap12 transmembrane domain in lipidic cubic2 phase Phyre2 PDB 2l34 chain A Region: 8 - 35 Aligned: 28 Modelled: 28 Confidence: 11.0% Identity: 21% PDB header:protein binding Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12 transmembrane homodimer Phyre2 PDB 4h1w chain B Region: 118 - 133 Aligned: 16 Modelled: 16 Confidence: 8.4% Identity: 25% PDB header:hydrolase/hydrolase regulator Chain: B: PDB Molecule:sarcolipin; PDBTitle: e1 structure of the (sr) ca2+-atpase in complex with sarcolipin Phyre2 PDB 3w5a chain C Region: 118 - 133 Aligned: 16 Modelled: 16 Confidence: 8.4% Identity: 25% PDB header:metal transport/membrane protein Chain: C: PDB Molecule:sarcolipin; PDBTitle: crystal structure of the calcium pump and sarcolipin from rabbit fast2 twitch skeletal muscle in the e1.mg2+ state Phyre2 PDB 1vp5 chain A Region: 161 - 194 Aligned: 34 Modelled: 34 Confidence: 8.2% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1k6n chain H Region: 22 - 45 Aligned: 24 Modelled: 24 Confidence: 7.5% Identity: 8% PDB header:photosynthesis Chain: H: PDB Molecule:photosynthetic reaction center h subunit; PDBTitle: e(l212)a,d(l213)a double mutant structure of photosynthetic reaction2 center from rhodobacter sphaeroides Phyre2 PDB 4v1a chain Q Region: 165 - 182 Aligned: 18 Modelled: 18 Confidence: 6.9% Identity: 33% PDB header:ribosome Chain: Q: PDB Molecule: PDBTitle: structure of the large subunit of the mammalian mitoribosome, part 22 of 2 Phyre2 PDB 1eys chain H Region: 22 - 45 Aligned: 24 Modelled: 24 Confidence: 5.9% Identity: 8% PDB header:electron transport Chain: H: PDB Molecule:photosynthetic reaction center; PDBTitle: crystal structure of photosynthetic reaction center from a2 thermophilic bacterium, thermochromatium tepidum Phyre2 PDB 1nbw chain A domain 3 Region: 133 - 201 Aligned: 61 Modelled: 69 Confidence: 5.8% Identity: 20% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: ATPase domain of dehydratase reactivase alpha subunit Phyre2 PDB 2i5n chain H Region: 22 - 36 Aligned: 15 Modelled: 15 Confidence: 5.7% Identity: 33% PDB header:photosynthesis Chain: H: PDB Molecule:reaction center protein h chain; PDBTitle: 1.96 a x-ray structure of photosynthetic reaction center from2 rhodopseudomonas viridis:crystals grown by microfluidic technique Phyre2 PDB 1yyb chain A Region: 158 - 176 Aligned: 19 Modelled: 19 Confidence: 5.5% Identity: 37% PDB header:apoptosis Chain: A: PDB Molecule:programmed cell death protein 5; PDBTitle: solution structure of 1-26 fragment of human programmed2 cell death 5 protein Phyre2 1 c4wpyA_ 2 d1gr0a1 3 d2fgga1 4 c5ydcA_ 5 d2axtm1 6 c3a0hm_ 7 d1q90b_ 8 c2l35B_ 9 c2l34B_ 10 c4wolA_ 11 c2l34A_ 12 c4h1wB_ 13 c3w5aC_ 14 d1vp5a_ 15 c1k6nH_ 16 c4v1aq_ 17 c1eysH_ 18 d1nbwa3 19 c2i5nH_ 20 c1yybA_ 21