1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	V	S	G	I	G	E	S	T	L	A	D	V	D	A	F	C	A	E	M	D	A	R	S	V	P	V	S	L	L	V	A	P	R	M	R	D	D	Y	R	L	D	R	D	P	R	T	V	D	W	L	T	G	R	R	A	A	G	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	V	L	H	G	Y	D	E	A	A	T	K	R	R	R	G	E	F	A	M	L	R	A	H	E	A	N	L	R	L	M	A	A	D	R	V	L	E	H	L	G	L	R	T	R	L	F	A	A	P	G	W	L	V	S	P	G	V	R
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	A	L	P	A	N	G	F	R	L	L	A	D	L	H	G	I	T	D	L	V	R	L	T	T	V	R	A	R	V	L	G	I	G	E	G	F	L	A	E	P	W	W	C	R	M	V	V	M	S	A	E	R	I	A	R	R	G	G	V
Secondary structure
SS confidence
Disorder																												?					?	?	?	?	?	?		?																?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.
Sequence		V	R	I	A	V	A	A	R	H	L	R	K	S	G	P	L	Q	A	M	L	D	A	V	D	L	A	M	L	Q	G	C	T	P	M	V	Y	R	W	R	A	D	A	A	V	L	D	A	A
Secondary structure
SS confidence
Disorder											?	?																					?		?									?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 50%) Beta strand ( 14%)

Rank Aligned region

PDB 3qbu chain D Region: 9 - 226 Aligned: 203 Modelled: 218 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: D: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of putative peptidoglycan deactelyase (hp0310) from2 helicobacter pylori Phyre2 PDB 1z7a chain A domain 1 Region: 7 - 227 Aligned: 205 Modelled: 221 Confidence: 100.0% Identity: 13% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: PA1517-like Phyre2 PDB 3rxz chain A Region: 7 - 226 Aligned: 205 Modelled: 220 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:polysaccharide deacetylase; PDBTitle: crystal structure of putative polysaccharide deacetylase from2 mycobacterium smegmatis Phyre2 PDB 3s6o chain D Region: 7 - 226 Aligned: 204 Modelled: 220 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: D: PDB Molecule:polysaccharide deacetylase family protein; PDBTitle: crystal structure of a polysaccharide deacetylase family protein from2 burkholderia pseudomallei Phyre2 PDB 2c1i chain A Region: 6 - 219 Aligned: 172 Modelled: 195 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:peptidoglycan glcnac deacetylase; PDBTitle: structure of streptococcus pneumoniae peptidoglycan deacetylase2 (sppgda) d 275 n mutant. Phyre2 PDB 4nz3 chain A Region: 7 - 216 Aligned: 199 Modelled: 210 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:deacetylase da1; PDBTitle: structure of vibrio cholerae chitin de-n-acetylase in complex with2 di(n-acetyl-d-glucosamine) (cbs) in p 21 21 21 Phyre2 PDB 2w3z chain A Region: 1 - 217 Aligned: 198 Modelled: 215 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative deacetylase; PDBTitle: structure of a streptococcus mutans ce4 esterase Phyre2 PDB 1w17 chain A Region: 1 - 219 Aligned: 182 Modelled: 203 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:probable polysaccharide deacetylase pdaa; PDBTitle: structure of bacillus subtilis pdaa, a family 4 carbohydrate esterase. Phyre2 PDB 5jp6 chain A Region: 7 - 216 Aligned: 166 Modelled: 191 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:putative polysaccharide deacetylase; PDBTitle: bdellovibrio bacteriovorus peptidoglycan deacetylase bd3279 Phyre2 PDB 4m1b chain A Region: 1 - 219 Aligned: 181 Modelled: 200 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:polysaccharide deacetylase; PDBTitle: structural determination of ba0150, a polysaccharide deacetylase from2 bacillus anthracis Phyre2 PDB 1ny1 chain A Region: 6 - 222 Aligned: 181 Modelled: 201 Confidence: 100.0% Identity: 12% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: NodB-like polysaccharide deacetylase Phyre2 PDB 2cc0 chain A domain 1 Region: 1 - 219 Aligned: 178 Modelled: 196 Confidence: 100.0% Identity: 12% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: NodB-like polysaccharide deacetylase Phyre2 PDB 2iw0 chain A domain 1 Region: 6 - 219 Aligned: 189 Modelled: 202 Confidence: 100.0% Identity: 10% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: NodB-like polysaccharide deacetylase Phyre2 PDB 5lgc chain A Region: 6 - 219 Aligned: 172 Modelled: 195 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:arce4a; PDBTitle: t48 deacetylase with substrate Phyre2 PDB 4l1g chain B Region: 6 - 219 Aligned: 178 Modelled: 195 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:peptidoglycan n-acetylglucosamine deacetylase; PDBTitle: crystal structure of the bc1960 peptidoglycan n-acetylglucosamine2 deacetylase from bacillus cereus Phyre2 PDB 5ncd chain A Region: 7 - 219 Aligned: 181 Modelled: 213 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:peptidoglycan n-acetylglucosamine deacetylase; PDBTitle: crystal structure of the polysaccharide deacetylase bc1974 from2 bacillus cereus in complex with (2s)-2-amino-5-3 (diaminomethylideneamino)-n-hydroxypentanamide Phyre2 PDB 2j13 chain A domain 1 Region: 6 - 219 Aligned: 160 Modelled: 180 Confidence: 100.0% Identity: 13% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: NodB-like polysaccharide deacetylase Phyre2 PDB 2iw0 chain A Region: 6 - 219 Aligned: 189 Modelled: 202 Confidence: 99.9% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:chitin deacetylase; PDBTitle: structure of the chitin deacetylase from the fungal2 pathogen colletotrichum lindemuthianum Phyre2 PDB 2c71 chain A domain 1 Region: 6 - 219 Aligned: 176 Modelled: 192 Confidence: 99.9% Identity: 14% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: NodB-like polysaccharide deacetylase Phyre2 PDB 2c1i chain A domain 1 Region: 6 - 219 Aligned: 172 Modelled: 195 Confidence: 99.9% Identity: 13% Fold: 7-stranded beta/alpha barrel Superfamily: Glycoside hydrolase/deacetylase Family: NodB-like polysaccharide deacetylase Phyre2 1 c3qbuD_ 2 d1z7aa1 3 c3rxzA_ 4 c3s6oD_ 5 c2c1iA_ 6 c4nz3A_ 7 c2w3zA_ 8 c1w17A_ 9 c5jp6A_ 10 c4m1bA_ 11 d1ny1a_ 12 d2cc0a1 13 d2iw0a1 14 c5lgcA_ 15 c4l1gB_ 16 c5ncdA_ 17 d2j13a1 18 c2iw0A_ 19 d2c71a1 20 d2c1ia1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161