1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	L	A	N	N	G	T	G	M	D	H	F	L	T	P	T	E	Y	L	D	A	G	H	P	L	V	R	T	T	A	A	T	L	I	R	D	A	V	S	D	T	E	R	V	R	R	I	Y	Y	Y	V	R	D	V	P	Y	D	V	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	S	F	R	Y	L	A	Q	G	H	H	R	A	S	D	V	I	G	H	G	V	A	F	C	M	G	K	A	S	S	F	V	A	L	C	R	A	A	G	V	P	A	R	I	A	F	Q	T	I	D	A	P	D	K	E	F	L	S	P	Q
Secondary structure
SS confidence
Disorder			?		?			?	?	?																																													?		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	R	A	L	W	G	G	R	T	G	R	P	F	P	W	H	S	L	G	E	A	Y	L	G	R	R	W	V	K	L	D	A	T	I	D	A	P	T	A	A	R	L	G	K	P	Y	R	Q	E	F	D	G	A	T	P	I	P	T	V	E
Secondary structure
SS confidence
Disorder			?	?	?	?		?	?	?	?																																											?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	T	I	L	R	E	N	G	S	Y	A	D	Y	P	S	A	V	A	Q	W	Y	E	R	I	A	Q	S	V	L	K	A	L	Q	S	T	E	V	H	A	L	V	A	A	D	E	E	L	W	T	G	P	P	V	E	L	A	D	A	T	H
Secondary structure
SS confidence
Disorder																																				?	?							?	?	?	?	?	?	?	?						?	?	?	?	?
Disorder confidence
		.	.
Sequence		R	L
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 36%) Beta strand ( 10%)

Rank Aligned region

PDB 3isr chain B Region: 1 - 170 Aligned: 146 Modelled: 152 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:transglutaminase-like enzymes, putative cysteine protease; PDBTitle: the crystal structure of a putative cysteine protease from cytophaga2 hutchinsonii to 1.9a Phyre2 PDB 6g49 chain A Region: 17 - 153 Aligned: 128 Modelled: 137 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:protein-glutamine gamma-glutamyltransferase; PDBTitle: crystal structure of the periplasmic domain of tgpa from pseudomonas2 aeruginosa Phyre2 PDB 4xz7 chain A Region: 25 - 156 Aligned: 111 Modelled: 117 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a tgase Phyre2 PDB 3kd4 chain A Region: 21 - 153 Aligned: 121 Modelled: 133 Confidence: 99.7% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative protease; PDBTitle: crystal structure of a putative protease (bdi_1141) from2 parabacteroides distasonis atcc 8503 at 2.00 a resolution Phyre2 PDB 2q3z chain A domain 4 Region: 24 - 153 Aligned: 125 Modelled: 130 Confidence: 99.7% Identity: 21% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 1g0d chain A domain 4 Region: 80 - 153 Aligned: 74 Modelled: 74 Confidence: 99.6% Identity: 22% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 2f4m chain A domain 1 Region: 68 - 156 Aligned: 64 Modelled: 64 Confidence: 99.6% Identity: 30% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 1vjj chain A domain 4 Region: 80 - 153 Aligned: 74 Modelled: 74 Confidence: 99.6% Identity: 23% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 1ex0 chain A domain 4 Region: 80 - 153 Aligned: 74 Modelled: 74 Confidence: 99.5% Identity: 27% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 1x3z chain A domain 1 Region: 72 - 156 Aligned: 60 Modelled: 60 Confidence: 99.2% Identity: 20% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 1kv3 chain F Region: 24 - 153 Aligned: 130 Modelled: 129 Confidence: 99.2% Identity: 21% PDB header:transferase Chain: F: PDB Molecule:protein-glutamine gamma-glutamyltransferase; PDBTitle: human tissue transglutaminase in gdp bound form Phyre2 PDB 1g0d chain A Region: 80 - 153 Aligned: 72 Modelled: 74 Confidence: 99.1% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:protein-glutamine gamma-glutamyltransferase; PDBTitle: crystal structure of red sea bream transglutaminase Phyre2 PDB 1f13 chain A Region: 80 - 153 Aligned: 72 Modelled: 74 Confidence: 99.1% Identity: 28% PDB header:coagulation factor Chain: A: PDB Molecule:cellular coagulation factor xiii zymogen; PDBTitle: recombinant human cellular coagulation factor xiii Phyre2 PDB 1l9m chain B Region: 80 - 153 Aligned: 71 Modelled: 74 Confidence: 99.1% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:protein-glutamine glutamyltransferase e3; PDBTitle: three-dimensional structure of the human transglutaminase 32 enzyme: binding of calcium ions change structure for3 activation Phyre2 PDB 4u65 chain F Region: 25 - 151 Aligned: 109 Modelled: 109 Confidence: 99.0% Identity: 16% PDB header:transferase/hydrolase Chain: F: PDB Molecule:putative cystine protease; PDBTitle: structure of the periplasmic output domain of the legionella2 pneumophila lapd ortholog cdgs9 in complex with pseudomonas3 fluorescens lapg Phyre2 PDB 2qsh chain A Region: 23 - 193 Aligned: 170 Modelled: 171 Confidence: 98.9% Identity: 12% PDB header:dna binding protein/dna Chain: A: PDB Molecule:dna repair protein rad4; PDBTitle: crystal structure of rad4-rad23 bound to a mismatch dna Phyre2 PDB 3esw chain A Region: 72 - 156 Aligned: 59 Modelled: 60 Confidence: 98.9% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:peptide-n(4)-(n-acetyl-beta-glucosaminyl)asparagine PDBTitle: complex of yeast pngase with glcnac2-iac. Phyre2 PDB 2pfr chain B Region: 26 - 183 Aligned: 141 Modelled: 145 Confidence: 98.0% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:arylamine n-acetyltransferase 2; PDBTitle: human n-acetyltransferase 2 Phyre2 PDB 4fgp chain B Region: 25 - 151 Aligned: 109 Modelled: 109 Confidence: 98.0% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:periplasmic protein; PDBTitle: legionella pneumophila lapg (egta-treated) Phyre2 PDB 1e2t chain A Region: 24 - 183 Aligned: 141 Modelled: 146 Confidence: 97.9% Identity: 12% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Arylamine N-acetyltransferase Phyre2 1 c3isrB_ 2 c6g49A_ 3 c4xz7A_ 4 c3kd4A_ 5 d2q3za4 6 d1g0da4 7 d2f4ma1 8 d1vjja4 9 d1ex0a4 10 d1x3za1 11 c1kv3F_ 12 c1g0dA_ 13 c1f13A_ 14 c1l9mB_ 15 c4u65F_ 16 c2qshA_ 17 c3eswA_ 18 c2pfrB_ 19 c4fgpB_ 20 d1e2ta_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99