1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	T	M	I	V	A	S	V	A	T	G	A	L	A	T	I	A	R	W	L	L	T	R	R	S	V	I	L	R	E	V	G	P	E	T	T	P	A	A	P	A	R	T	A	E	L	G	L	S	G	A	G	P	T	V	V	H	F	R
Secondary structure
SS confidence
Disorder		?	?																			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	P	G	C	A	P	C	D	R	V	R	R	G	V	G	D	V	C	A	D	L	G	D	V	A	H	I	E	V	D	L	D	S	N	P	Q	A	A	R	R	F	S	V	L	S	L	P	T	T	L	I	F	D	V	D	G	R	Q	R	Y
Secondary structure
SS confidence
Disorder																																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence		R	T	S	G	V	P	K	A	A	D	L	R	S	A	L	K	P	L	L	A
Secondary structure
SS confidence
Disorder				?	?	?														?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 44%) Beta strand ( 19%)

Rank Aligned region

PDB 2ppt chain A Region: 30 - 139 Aligned: 109 Modelled: 110 Confidence: 99.9% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin-2; PDBTitle: crystal structure of thioredoxin-2 Phyre2 PDB 6ibl chain B Region: 34 - 140 Aligned: 106 Modelled: 107 Confidence: 99.9% Identity: 19% PDB header:immune system Chain: B: PDB Molecule:thioredoxin 1,beta-1 adrenergic receptor; PDBTitle: activated turkey beta1 adrenoceptor with bound agonist formoterol and2 nanobody nb80 Phyre2 PDB 5e37 chain A Region: 47 - 140 Aligned: 92 Modelled: 94 Confidence: 99.9% Identity: 23% PDB header:oxidoreductase Chain: A: PDB Molecule:ef-hand domain-containing thioredoxin; PDBTitle: redox protein from chlamydomonas reinhardtii Phyre2 PDB 2l57 chain A Region: 28 - 138 Aligned: 111 Modelled: 111 Confidence: 99.9% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of an uncharacterized thioredoin-like protein from2 clostridium perfringens Phyre2 PDB 3p2a chain B Region: 30 - 140 Aligned: 110 Modelled: 111 Confidence: 99.9% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis Phyre2 PDB 2l6d chain A Region: 49 - 138 Aligned: 89 Modelled: 90 Confidence: 99.9% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of desulfothioredoxin from desulfovibrio vulgaris2 hildenborough in its reduced form Phyre2 PDB 2lrc chain A Region: 35 - 140 Aligned: 105 Modelled: 106 Confidence: 99.9% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:probable thioredoxin; PDBTitle: structure of thioredoxin 2 from pseudomonas aeruginosa pao1 in its2 reduced form Phyre2 PDB 3p2a chain A Region: 30 - 140 Aligned: 110 Modelled: 111 Confidence: 99.9% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin-like protein; PDBTitle: crystal structure of thioredoxin 2 from yersinia pestis Phyre2 PDB 6gc1 chain A Region: 25 - 139 Aligned: 115 Modelled: 115 Confidence: 99.9% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:nhl repeat-containing protein 2; PDBTitle: crystal structure of trx-like and nhl repeat containing domains of2 human nhlrc2 Phyre2 PDB 6ckp chain A Region: 22 - 140 Aligned: 118 Modelled: 119 Confidence: 99.9% Identity: 26% PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of a thioredoxin domain 2 from brucella melitensis2 at 1.15 angstrom resolution Phyre2 PDB 3d22 chain A Region: 43 - 139 Aligned: 95 Modelled: 97 Confidence: 99.9% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h-type; PDBTitle: crystal structure of a poplar thioredoxin h mutant, pttrxh4c61s Phyre2 PDB 3hyp chain B Region: 49 - 140 Aligned: 91 Modelled: 92 Confidence: 99.9% Identity: 22% PDB header:electron transport Chain: B: PDB Molecule:thioredoxin; PDBTitle: crystal structure of bacteroides fragilis trxp_s105g mutant Phyre2 PDB 1xfl chain A Region: 43 - 140 Aligned: 96 Modelled: 98 Confidence: 99.9% Identity: 24% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 2vlv chain A Region: 43 - 140 Aligned: 96 Modelled: 98 Confidence: 99.9% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h isoform 2.; PDBTitle: crystal structure of barley thioredoxin h isoform 2 in partially2 radiation-reduced state Phyre2 PDB 3qdn chain A Region: 29 - 139 Aligned: 110 Modelled: 111 Confidence: 99.9% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium Phyre2 PDB 3hz4 chain A Region: 33 - 140 Aligned: 107 Modelled: 105 Confidence: 99.9% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei Phyre2 PDB 3dxb chain E Region: 40 - 140 Aligned: 100 Modelled: 101 Confidence: 99.9% Identity: 22% PDB header:splicing, transcription Chain: E: PDB Molecule:thioredoxin n-terminally fused to puf60(uhm); PDBTitle: structure of the uhm domain of puf60 fused to thioredoxin Phyre2 PDB 2l5l chain A Region: 49 - 140 Aligned: 91 Modelled: 92 Confidence: 99.9% Identity: 22% PDB header:transport protein Chain: A: PDB Molecule:thioredoxin; PDBTitle: solution structure of thioredoxin from bacteroides vulgatus Phyre2 PDB 2trx chain A Region: 33 - 140 Aligned: 107 Modelled: 108 Confidence: 99.9% Identity: 21% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 3gnj chain D Region: 33 - 139 Aligned: 106 Modelled: 105 Confidence: 99.9% Identity: 17% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb Phyre2 1 c2pptA_ 2 c6iblB_ 3 c5e37A_ 4 c2l57A_ 5 c3p2aB_ 6 c2l6dA_ 7 c2lrcA_ 8 c3p2aA_ 9 c6gc1A_ 10 c6ckpA_ 11 c3d22A_ 12 c3hypB_ 13 d1xfla_ 14 c2vlvA_ 15 c3qdnA_ 16 c3hz4A_ 17 c3dxbE_ 18 c2l5lA_ 19 d2trxa_ 20 c3gnjD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489