1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	M	R	K	V	L	V	G	V	T	G	A	A	I	V	V	A	V	L	I	V	G	A	V	G	A	D	F	G	A	S	I	Y	A	E	Y	R	L	S	T	T	V	R	K	A	A	N	L	R	S	D	P	F	V	A	I	L	R	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	F	I	P	Q	A	M	R	E	H	Y	A	E	L	E	I	K	A	F	A	V	E	H	A	G	S	G	T	A	T	L	E	A	T	M	H	S	I	D	L	S	Y	A	S	W	L	I	R	P	D	A	K	L	P	V	G	E	L	E	S
Secondary structure
SS confidence
Disorder										?												?	?	?	?				?																			?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	I	I	I	D	S	M	H	L	G	R	Y	L	G	I	S	D	L	M	V	A	A	P	R	Q	E	S	N	D	A	T	G	G	T	T	E	S	G	I	S	G	S	R	G	L	V	F	S	G	T	P	I	S	A	N	F	A	H	R	V
Secondary structure
SS confidence
Disorder											?						?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?							?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	V	L	V	D	L	S	V	A	S	D	D	R	A	T	L	V	I	T	P	T	A	V	V	T	G	P	D	T	A	D	Q	P	V	P	D	D	K	R	D	A	V	L	H	A	F	A	S	K	L	P	N	Q	K	L	P	F	G	V	V
Secondary structure
SS confidence
Disorder											?	?		?	?							?				?	?	?	?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270
Sequence		P	N	T	V	G	A	R	G	S	D	V	I	I	E	G	I	T	R	G	V	T	I	S	L	D	E	F	K	Q	S
Secondary structure
SS confidence
Disorder		?																									?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 26%) Beta strand ( 40%) TM helix ( 6%) (View membrane topology prediction)

Rank Aligned region

PDB 1ghh chain A Region: 214 - 259 Aligned: 45 Modelled: 46 Confidence: 17.1% Identity: 16% Fold: DNA damage-inducible protein DinI Superfamily: DNA damage-inducible protein DinI Family: DNA damage-inducible protein DinI Phyre2 PDB 2f9w chain A domain 2 Region: 25 - 41 Aligned: 17 Modelled: 17 Confidence: 16.6% Identity: 24% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: CoaX-like Phyre2 PDB 2g3w chain A domain 1 Region: 214 - 269 Aligned: 46 Modelled: 46 Confidence: 14.3% Identity: 13% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: YaeQ-like Phyre2 PDB 1hyo chain A domain 1 Region: 227 - 239 Aligned: 13 Modelled: 13 Confidence: 13.6% Identity: 54% Fold: SH3-like barrel Superfamily: Fumarylacetoacetate hydrolase, FAH, N-terminal domain Family: Fumarylacetoacetate hydrolase, FAH, N-terminal domain Phyre2 PDB 3c0u chain A Region: 214 - 269 Aligned: 46 Modelled: 46 Confidence: 13.3% Identity: 11% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein yaeq; PDBTitle: crystal structure of e.coli yaeq protein Phyre2 PDB 3dzm chain B Region: 232 - 265 Aligned: 34 Modelled: 33 Confidence: 12.5% Identity: 44% PDB header:unknown function Chain: B: PDB Molecule:hypothetical conserved protein; PDBTitle: crystal structure of a major outer membrane protein from thermus2 thermophilus hb27 Phyre2 PDB 6cfw chain E Region: 3 - 42 Aligned: 40 Modelled: 40 Confidence: 11.9% Identity: 15% PDB header:membrane protein Chain: E: PDB Molecule:mbh subunit; PDBTitle: cryoem structure of a respiratory membrane-bound hydrogenase Phyre2 PDB 2ddh chain A Region: 58 - 108 Aligned: 51 Modelled: 51 Confidence: 9.4% Identity: 6% PDB header:oxidoreductase Chain: A: PDB Molecule:acyl-coa oxidase; PDBTitle: crystal structure of acyl-coa oxidase complexed with 3-oh-dodecanoate Phyre2 PDB 2bpa chain 1 Region: 57 - 73 Aligned: 17 Modelled: 17 Confidence: 9.3% Identity: 29% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: ssDNA viruses Family: Microviridae-like VP Phyre2 PDB 5ys9 chain A Region: 58 - 108 Aligned: 51 Modelled: 51 Confidence: 9.2% Identity: 6% PDB header:oxidoreductase Chain: A: PDB Molecule:acyl-coenzyme a oxidase 3; PDBTitle: crystal structure of acyl-coa oxidase3 from yarrowia lipolytica Phyre2 PDB 2knc chain A Region: 1 - 25 Aligned: 25 Modelled: 25 Confidence: 8.7% Identity: 32% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 6ey4 chain A Region: 148 - 265 Aligned: 99 Modelled: 118 Confidence: 8.6% Identity: 9% PDB header:protein transport Chain: A: PDB Molecule:gldm; PDBTitle: periplasmic domain (residues 36-513) of gldm Phyre2 PDB 1kvp chain A Region: 57 - 73 Aligned: 17 Modelled: 17 Confidence: 8.2% Identity: 29% Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily: ssDNA viruses Family: Microviridae-like VP Phyre2 PDB 6giy chain A Region: 38 - 73 Aligned: 36 Modelled: 36 Confidence: 8.2% Identity: 17% PDB header:structural protein Chain: A: PDB Molecule:tssf; PDBTitle: the baseplate complex from the type vi secretion system Phyre2 PDB 4c47 chain B Region: 58 - 98 Aligned: 41 Modelled: 41 Confidence: 6.7% Identity: 12% PDB header:cell adhesion Chain: B: PDB Molecule:inner membrane lipoprotein; PDBTitle: salmonella enterica trimeric lipoprotein sadb Phyre2 PDB 5k3j chain A Region: 60 - 119 Aligned: 60 Modelled: 60 Confidence: 6.5% Identity: 8% PDB header:oxidoreductase Chain: A: PDB Molecule:acyl-coenzyme a oxidase; PDBTitle: crystals structure of acyl-coa oxidase-2 in caenorhabditis elegans2 bound with fad, ascaroside-coa, and atp Phyre2 PDB 5y9d chain A Region: 58 - 108 Aligned: 51 Modelled: 51 Confidence: 5.7% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:acyl-coenzyme a oxidase 1; PDBTitle: crystal structure of acyl-coa oxidase1 from yarrowia lipolytica Phyre2 PDB 2lif chain A Region: 58 - 62 Aligned: 5 Modelled: 5 Confidence: 5.7% Identity: 60% PDB header:viral protein, membrane protein Chain: A: PDB Molecule:core protein p21; PDBTitle: solution structure of kkgf Phyre2 PDB 1qd1 chain A domain 2 Region: 35 - 99 Aligned: 42 Modelled: 65 Confidence: 5.4% Identity: 12% Fold: Ferredoxin-like Superfamily: Formiminotransferase domain of formiminotransferase-cyclodeaminase. Family: Formiminotransferase domain of formiminotransferase-cyclodeaminase. Phyre2 PDB 2b7o chain A domain 1 Region: 249 - 263 Aligned: 15 Modelled: 15 Confidence: 5.3% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class-II DAHP synthetase Phyre2 1 d1ghha_ 2 d2f9wa2 3 d2g3wa1 4 d1hyoa1 5 c3c0uA_ 6 c3dzmB_ 7 c6cfwE_ 8 c2ddhA_ 9 d2bpa1_ 10 c5ys9A_ 11 c2kncA_ 12 c6ey4A_ 13 d1kvpa_ 14 c6giyA_ 15 c4c47B_ 16 c5k3jA_ 17 c5y9dA_ 18 c2lifA_ 19 d1qd1a2 20 d2b7oa1 21 22