1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	A	G	M	A	G	F	R	R	W	A	Q	T	N	D	P	T	A	H	A	E	S	L	A	I	R	A	A	C	T	K	L	G	T	E	H	L	V	G	T	T	L	N	V	L	A	H	P	C	P	M	C	Y	G	S	L	Y	Y	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	P	D	E	V	V	F	L	T	S	R	D	A	Y	E	P	H	Y	V	D	D	R	R	Y	F	E	P	A	T	F	Y	D	E	F	A	K	E	W	Q	D	R	R	L	P	M	R	Q	E	H	R	P	D	I	R	A	G	A	V	D	V
Secondary structure
SS confidence
Disorder																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence		Y	R	F	R	Q	E	P	N	G	G	E	R	S	A	I	A	A	P	T	G
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 16%) Alpha helix ( 51%) Beta strand ( 7%)

Rank Aligned region

PDB 2g84 chain A domain 1 Region: 6 - 130 Aligned: 116 Modelled: 125 Confidence: 100.0% Identity: 27% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 1wkq chain A Region: 6 - 131 Aligned: 116 Modelled: 126 Confidence: 100.0% Identity: 29% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 2nx8 chain A Region: 6 - 124 Aligned: 106 Modelled: 109 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:trna-specific adenosine deaminase; PDBTitle: the crystal structure of the trna-specific adenosine deaminase from2 streptococcus pyogenes Phyre2 PDB 3ocq chain A Region: 6 - 126 Aligned: 108 Modelled: 121 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/adenosine deaminase; PDBTitle: crystal structure of trna-specific adenosine deaminase from salmonella2 enterica Phyre2 PDB 1z3a chain A domain 1 Region: 6 - 133 Aligned: 115 Modelled: 118 Confidence: 99.9% Identity: 23% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 1wwr chain A domain 1 Region: 6 - 127 Aligned: 108 Modelled: 112 Confidence: 99.9% Identity: 26% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 2b3j chain A domain 1 Region: 6 - 128 Aligned: 110 Modelled: 123 Confidence: 99.9% Identity: 24% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 3dh1 chain D Region: 6 - 127 Aligned: 111 Modelled: 122 Confidence: 99.9% Identity: 21% PDB header:hydrolase Chain: D: PDB Molecule:trna-specific adenosine deaminase 2; PDBTitle: crystal structure of human trna-specific adenosine-34 deaminase2 subunit adat2 Phyre2 PDB 5xkr chain A Region: 6 - 127 Aligned: 117 Modelled: 118 Confidence: 99.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:cmp/dcmp deaminase, zinc-binding protein; PDBTitle: crystal structure of msmeg3575 in complex with benzoguanamine Phyre2 PDB 5jfy chain C Region: 6 - 80 Aligned: 75 Modelled: 75 Confidence: 99.9% Identity: 32% PDB header:hydrolase Chain: C: PDB Molecule:deoxycytidine deaminase; PDBTitle: crystal structure of a plant cytidine deaminase Phyre2 PDB 2a8n chain A domain 1 Region: 6 - 86 Aligned: 81 Modelled: 81 Confidence: 99.9% Identity: 30% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 1p6o chain A Region: 6 - 124 Aligned: 97 Modelled: 102 Confidence: 99.9% Identity: 18% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 2b3z chain A domain 2 Region: 6 - 124 Aligned: 93 Modelled: 102 Confidence: 99.9% Identity: 19% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 PDB 2o7p chain A Region: 6 - 124 Aligned: 92 Modelled: 103 Confidence: 99.9% Identity: 23% PDB header:hydrolase, oxidoreductase Chain: A: PDB Molecule:riboflavin biosynthesis protein ribd; PDBTitle: the crystal structure of ribd from escherichia coli in complex with2 the oxidised nadp+ cofactor in the active site of the reductase3 domain Phyre2 PDB 2d5n chain B Region: 6 - 127 Aligned: 96 Modelled: 101 Confidence: 99.8% Identity: 18% PDB header:hydrolase, oxidoreductase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribd; PDBTitle: crystal structure of a bifunctional deaminase and reductase2 involved in riboflavin biosynthesis Phyre2 PDB 4p9e chain A Region: 6 - 75 Aligned: 68 Modelled: 70 Confidence: 99.8% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:deoxycytidylate deaminase; PDBTitle: crystal structure of dcmp deaminase from the cyanophage s-tim5 in apo2 form Phyre2 PDB 2w4l chain C Region: 6 - 90 Aligned: 77 Modelled: 85 Confidence: 99.8% Identity: 23% PDB header:hydrolase Chain: C: PDB Molecule:deoxycytidylate deaminase; PDBTitle: human dcmp deaminase Phyre2 PDB 3zpg chain A Region: 6 - 124 Aligned: 93 Modelled: 102 Confidence: 99.8% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:ribd; PDBTitle: acinetobacter baumannii ribd, form 2 Phyre2 PDB 2hxv chain A Region: 6 - 124 Aligned: 95 Modelled: 98 Confidence: 99.8% Identity: 23% PDB header:biosynthetic protein Chain: A: PDB Molecule:diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5- PDBTitle: crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine2 deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828)3 from thermotoga maritima at 1.80 a resolution Phyre2 PDB 1vq2 chain A Region: 6 - 113 Aligned: 90 Modelled: 108 Confidence: 99.8% Identity: 19% Fold: Cytidine deaminase-like Superfamily: Cytidine deaminase-like Family: Deoxycytidylate deaminase-like Phyre2 1 d2g84a1 2 d1wkqa_ 3 c2nx8A_ 4 c3ocqA_ 5 d1z3aa1 6 d1wwra1 7 d2b3ja1 8 c3dh1D_ 9 c5xkrA_ 10 c5jfyC_ 11 d2a8na1 12 d1p6oa_ 13 d2b3za2 14 c2o7pA_ 15 c2d5nB_ 16 c4p9eA_ 17 c2w4lC_ 18 c3zpgA_ 19 c2hxvA_ 20 d1vq2a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86