1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	V	G	A	Q	C	R	D	L	L	H	W	R	F	C	R	G	V	P	P	R	A	T	N	D	T	D	I	A	G	T	L	N	N	W	D	H	F	E	A	I	R	A	T	F	R	A	L	G	S	T	G	H	R	F	L	I	A	D
Secondary structure
SS confidence
Disorder		?		?	?										?		?	?	?	?	?	?																											?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	A	V	D	A	L	P	F	G	E	V	E	S	P	T	G	T	T	R	H	P	P	G	N	Q	L	M	N	V	H	G	C	T	D	A	Y	L	R	A	D	V	L	P	L	P	G	G	L	T	V	H	L	P	Q	P	P	N	Y	A	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	K	L	H	A	W	L	D	R	S	A	D	H	D	Y	K	D	G	P	D	L	A	L	V	V	H	W	Y	A	G	D	L	D	R	L	Y	A	K	P	D	Q	W	A	L	R	R	H	D	F	D	L	R	T	A	A	A	A	L	L	G
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.
Sequence		H	D	M	R	A	S	V	S	A	P	E	A	A	V	L	A	T	R	A	T	Q	A	D	H	D	L	L	A	Q	H	F	A	V	G	R	P	G
Secondary structure
SS confidence
Disorder																						?	?	?	?									?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 48%) Beta strand ( 16%)

Rank Aligned region

PDB 5uvd chain A Region: 1 - 166 Aligned: 158 Modelled: 166 Confidence: 99.4% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:nucleotidyltransferase-like protein; PDBTitle: crystal structure of an antigenic nucleotidyltransferase-like protein2 from paracoccidioides brasiliensis Phyre2 PDB 4wqk chain A Region: 1 - 148 Aligned: 128 Modelled: 145 Confidence: 99.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:2''-aminoglycoside nucleotidyltransferase; PDBTitle: crystal structure of aminoglycoside nucleotidylyltransferase ant(2")-2 ia, apo form Phyre2 PDB 4e8i chain A Region: 1 - 146 Aligned: 125 Modelled: 146 Confidence: 98.2% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:lincosamide resistance protein; PDBTitle: crystal structure of lincosamide antibiotic adenylyltransferase lina,2 apo Phyre2 PDB 4ok0 chain B Region: 20 - 149 Aligned: 108 Modelled: 110 Confidence: 97.4% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:putative; PDBTitle: crystal structure of putative nucleotidyltransferase from h. pylori Phyre2 PDB 1vfg chain B Region: 1 - 68 Aligned: 60 Modelled: 60 Confidence: 96.9% Identity: 15% PDB header:transferase/rna Chain: B: PDB Molecule:poly a polymerase; PDBTitle: crystal structure of trna nucleotidyltransferase complexed2 with a primer trna and an incoming atp analog Phyre2 PDB 4x4w chain B Region: 1 - 98 Aligned: 79 Modelled: 98 Confidence: 96.1% Identity: 19% PDB header:rna binding protein Chain: B: PDB Molecule:cca trna nucleotidyltransferase 1, mitochondrial; PDBTitle: crystal structure of the full-length human mitochondrial cca-adding2 enzyme Phyre2 PDB 1vfg chain A domain 2 Region: 1 - 68 Aligned: 60 Modelled: 68 Confidence: 95.7% Identity: 17% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 3h37 chain B Region: 1 - 68 Aligned: 59 Modelled: 68 Confidence: 95.1% Identity: 27% PDB header:transferase Chain: B: PDB Molecule:trna nucleotidyl transferase-related protein; PDBTitle: the structure of cca-adding enzyme apo form i Phyre2 PDB 6q52 chain A Region: 1 - 68 Aligned: 56 Modelled: 60 Confidence: 95.1% Identity: 23% PDB header:rna binding protein Chain: A: PDB Molecule:cca-adding enzyme; PDBTitle: structure of a psychrophilic cca-adding enzyme in complex with cmpcpp2 at room temperature in chipx microfluidic device Phyre2 PDB 1r89 chain A domain 2 Region: 1 - 79 Aligned: 70 Modelled: 79 Confidence: 94.7% Identity: 20% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Archaeal tRNA CCA-adding enzyme catalytic domain Phyre2 PDB 1ou5 chain A domain 2 Region: 1 - 52 Aligned: 40 Modelled: 44 Confidence: 94.5% Identity: 28% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 PDB 1miy chain B Region: 1 - 68 Aligned: 59 Modelled: 68 Confidence: 94.3% Identity: 29% PDB header:translation, transferase Chain: B: PDB Molecule:trna cca-adding enzyme; PDBTitle: crystal structure of bacillus stearothermophilus cca-adding enzyme in2 complex with ctp Phyre2 PDB 3wfs chain D Region: 1 - 68 Aligned: 63 Modelled: 68 Confidence: 94.1% Identity: 21% PDB header:transferase/rna Chain: D: PDB Molecule:poly a polymerase; PDBTitle: trna processing enzyme complex 3 Phyre2 PDB 3wfp chain A Region: 1 - 68 Aligned: 63 Modelled: 68 Confidence: 94.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:poly a polymerase; PDBTitle: trna processing enzyme (apo form 2) Phyre2 PDB 3wfr chain G Region: 1 - 68 Aligned: 63 Modelled: 68 Confidence: 93.9% Identity: 21% PDB header:transferase/rna Chain: G: PDB Molecule:poly a polymerase; PDBTitle: trna processing enzyme complex 2 Phyre2 PDB 3aqn chain A Region: 1 - 68 Aligned: 59 Modelled: 60 Confidence: 93.6% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:poly(a) polymerase; PDBTitle: complex structure of bacterial protein (apo form ii) Phyre2 PDB 3wfr chain H Region: 1 - 68 Aligned: 63 Modelled: 68 Confidence: 92.9% Identity: 21% PDB header:transferase/rna Chain: H: PDB Molecule:poly a polymerase; PDBTitle: trna processing enzyme complex 2 Phyre2 PDB 3wfo chain B Region: 1 - 65 Aligned: 60 Modelled: 65 Confidence: 92.7% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:poly a polymerase; PDBTitle: trna processing enzyme (apo form 1) Phyre2 PDB 3wfr chain E Region: 1 - 49 Aligned: 44 Modelled: 49 Confidence: 92.5% Identity: 18% PDB header:transferase/rna Chain: E: PDB Molecule:poly a polymerase; PDBTitle: trna processing enzyme complex 2 Phyre2 PDB 1miw chain A domain 2 Region: 1 - 42 Aligned: 33 Modelled: 34 Confidence: 92.5% Identity: 39% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: Poly A polymerase head domain-like Phyre2 1 c5uvdA_ 2 c4wqkA_ 3 c4e8iA_ 4 c4ok0B_ 5 c1vfgB_ 6 c4x4wB_ 7 d1vfga2 8 c3h37B_ 9 c6q52A_ 10 d1r89a2 11 d1ou5a2 12 c1miyB_ 13 c3wfsD_ 14 c3wfpA_ 15 c3wfrG_ 16 c3aqnA_ 17 c3wfrH_ 18 c3wfoB_ 19 c3wfrE_ 20 d1miwa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68