1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	A	A	S	I	V	H	H	S	A	A	P	A	N	R	G	R	Y	H	G	I	W	S	M	T	P	V	V	A	S	V	V	V	P	I	M	A	S	Y	G	P	I	H	G	A	H	L	L	A	A	V	V	V	G	S	A	G	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?		?	?	?	?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Sequence		L	C	L	P	L	A	R	A	L	R	R	P	T	P	S	A	M	T	T	D
Secondary structure
SS confidence
Disorder									?	?			?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 34%) Alpha helix ( 78%) Beta strand ( 2%)

Rank Aligned region

PDB 5aym chain A Region: 5 - 71 Aligned: 67 Modelled: 67 Confidence: 62.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 39 (iron-regulated transporter); PDBTitle: crystal structure of a bacterial homologue of iron transporter2 ferroportin in outward-facing state with soaked iron Phyre2 PDB 5ayn chain A Region: 5 - 71 Aligned: 67 Modelled: 67 Confidence: 59.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 39 (iron-regulated transporter); PDBTitle: crystal structure of a bacterial homologue of iron transporter2 ferroportin in outward-facing state Phyre2 PDB 4iky chain A Region: 2 - 71 Aligned: 70 Modelled: 70 Confidence: 49.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:di-tripeptide abc transporter (permease); PDBTitle: crystal structure of peptide transporter pot (e310q mutant) in complex2 with sulfate Phyre2 PDB 3wdo chain A Region: 5 - 76 Aligned: 71 Modelled: 72 Confidence: 46.0% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:mfs transporter; PDBTitle: structure of e. coli yajr transporter Phyre2 PDB 4w6v chain A Region: 5 - 71 Aligned: 67 Modelled: 67 Confidence: 33.6% Identity: 16% PDB header:transport protein Chain: A: PDB Molecule:di-/tripeptide transporter; PDBTitle: crystal structure of a peptide transporter from yersinia2 enterocolitica at 3 a resolution Phyre2 PDB 6exs chain A Region: 5 - 71 Aligned: 67 Modelled: 67 Confidence: 23.2% Identity: 13% PDB header:membrane protein Chain: A: PDB Molecule:peptide abc transporter permease; PDBTitle: crystal structure of a pot family transporter in complex with2 thioalcohol conjugated peptide. Phyre2 PDB 4o9t chain H Region: 53 - 75 Aligned: 23 Modelled: 23 Confidence: 18.7% Identity: 43% PDB header:membrane protein Chain: H: PDB Molecule:nad(p) transhydrogenase subunit beta; PDBTitle: mechanism of transhydrogenase coupling proton translocation and2 hydride transfer Phyre2 PDB 6e9o chain A Region: 1 - 71 Aligned: 71 Modelled: 71 Confidence: 14.0% Identity: 21% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 6gs7 chain A Region: 5 - 71 Aligned: 67 Modelled: 67 Confidence: 11.5% Identity: 22% PDB header:membrane protein Chain: A: PDB Molecule:dipeptide and tripeptide permease a; PDBTitle: crystal structure of peptide transporter dtpa-nanobody in glycine2 buffer Phyre2 PDB 6g9x chain B Region: 5 - 73 Aligned: 69 Modelled: 69 Confidence: 11.4% Identity: 13% PDB header:membrane protein Chain: B: PDB Molecule:major facilitator superfamily mfs_1; PDBTitle: crystal structure of a mfs transporter at 2.54 angstroem resolution Phyre2 PDB 2mic chain B Region: 48 - 56 Aligned: 9 Modelled: 9 Confidence: 10.1% Identity: 78% PDB header:membrane protein Chain: B: PDB Molecule:tumor necrosis factor receptor superfamily member 16; PDBTitle: nmr structure of p75 transmembrane domain in dpc micelles Phyre2 PDB 2mic chain A Region: 48 - 56 Aligned: 9 Modelled: 9 Confidence: 10.1% Identity: 78% PDB header:membrane protein Chain: A: PDB Molecule:tumor necrosis factor receptor superfamily member 16; PDBTitle: nmr structure of p75 transmembrane domain in dpc micelles Phyre2 PDB 1s6c chain B Region: 57 - 68 Aligned: 12 Modelled: 12 Confidence: 9.0% Identity: 67% PDB header:transport protein Chain: B: PDB Molecule:potassium voltage-gated channel subfamily d member 2; PDBTitle: crystal structure of the complex between kchip1 and kv4.2 n1-30 Phyre2 PDB 5aez chain A Region: 18 - 71 Aligned: 54 Modelled: 54 Confidence: 8.9% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:mep2; PDBTitle: crystal structure of candida albicans mep2 Phyre2 PDB 4o9u chain B Region: 53 - 72 Aligned: 20 Modelled: 20 Confidence: 8.0% Identity: 45% PDB header:membrane protein Chain: B: PDB Molecule:nad(p) transhydrogenase subunit beta; PDBTitle: mechanism of transhydrogenase coupling proton translocation and2 hydride transfer Phyre2 PDB 1u7g chain A Region: 20 - 71 Aligned: 52 Modelled: 49 Confidence: 7.2% Identity: 13% Fold: Ammonium transporter Superfamily: Ammonium transporter Family: Ammonium transporter Phyre2 PDB 4ole chain D Region: 12 - 26 Aligned: 15 Modelled: 15 Confidence: 7.0% Identity: 40% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:next to brca1 gene 1 protein; PDBTitle: crystal structure of a neighbor of brca1 gene 1 (nbr1) from homo2 sapiens at 2.52 a resolution Phyre2 PDB 5aex chain J Region: 18 - 71 Aligned: 54 Modelled: 54 Confidence: 6.9% Identity: 15% PDB header:membrane protein Chain: J: PDB Molecule:ammonium transporter mep2; PDBTitle: crystal structure of saccharomyces cerevisiae mep2 Phyre2 PDB 1pv7 chain B Region: 5 - 74 Aligned: 70 Modelled: 70 Confidence: 6.8% Identity: 13% PDB header:transport protein Chain: B: PDB Molecule:lactose permease; PDBTitle: crystal structure of lactose permease with tdg Phyre2 PDB 1pv7 chain A Region: 5 - 74 Aligned: 70 Modelled: 70 Confidence: 6.8% Identity: 13% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: LacY-like proton/sugar symporter Phyre2 1 c5aymA_ 2 c5aynA_ 3 c4ikyA_ 4 c3wdoA_ 5 c4w6vA_ 6 c6exsA_ 7 c4o9tH_ 8 c6e9oA_ 9 c6gs7A_ 10 c6g9xB_ 11 c2micB_ 12 c2micA_ 13 c1s6cB_ 14 c5aezA_ 15 c4o9uB_ 16 d1u7ga_ 17 c4oleD_ 18 c5aexJ_ 19 c1pv7B_ 20 d1pv7a_ 21 22