1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	A	R	A	I	F	R	G	F	N	R	P	S	R	V	L	M	I	N	Q	F	G	I	N	I	G	F	Y	M	L	M	P	Y	L	A	D	Y	L	A	G	P	L	G	L	A	A	W	A	V	G	L	V	M	G	V	R	N	F	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	Q	G	M	F	F	V	G	G	T	L	A	D	R	F	G	Y	K	P	L	I	I	A	G	C	L	I	R	T	G	G	F	A	L	L	V	V	A	Q	S	L	P	S	V	L	I	A	A	A	A	T	G	F	A	G	A	L	F	N	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	V	R	G	Y	L	A	A	E	A	G	E	R	K	I	E	A	F	A	M	F	N	V	F	Y	Q	S	G	I	L	L	G	P	L	V	G	L	V	L	L	A	L	D	F	R	I	T	V	L	A	A	A	G	V	F	G	L	L	T	V
Secondary structure
SS confidence
Disorder									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	Q	L	V	A	L	P	Q	H	R	A	D	S	E	R	E	K	T	S	I	L	Q	D	W	R	V	V	V	R	N	R	P	F	L	T	L	A	A	A	M	T	G	C	Y	A	L	S	F	Q	I	Y	L	A	L	P	M	Q	A	S	I
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	M	P	R	N	Q	Y	L	L	I	A	A	M	F	A	V	S	G	L	V	A	V	G	G	Q	L	R	I	T	R	W	F	A	V	R	W	G	A	E	R	S	L	V	V	G	A	T	I	L	A	A	S	F	I	P	V	A	V	I	P
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		N	G	Q	R	F	G	V	A	V	A	V	M	A	L	V	L	S	A	S	L	L	A	V	A	S	A	A	L	F	P	F	E	M	R	A	V	V	A	L	S	G	D	R	L	V	A	T	H	Y	G	F	Y	S	T	I	V	G	V	G	V
Secondary structure
SS confidence
Disorder			?	?	?	?																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.
Sequence		L	V	G	N	L	A	I	G	S	L	M	S	A	A	R	R	L	N	T	D	E	I	V	W	G	G	L	I	L	V	G	I	V	A	V	A	G	L	R	R	L	D	T	F	T	S	G	S	Q	N	M	T	G	R	W	A	A	P	R
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 82%) Beta strand ( 0%) TM helix ( 62%) (View membrane topology prediction)

Rank Aligned region

PDB 3wdo chain A Region: 3 - 417 Aligned: 405 Modelled: 415 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:mfs transporter; PDBTitle: structure of e. coli yajr transporter Phyre2 PDB 6e9o chain A Region: 8 - 403 Aligned: 389 Modelled: 396 Confidence: 100.0% Identity: 11% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 1pv7 chain A Region: 11 - 416 Aligned: 405 Modelled: 406 Confidence: 100.0% Identity: 10% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: LacY-like proton/sugar symporter Phyre2 PDB 6exs chain A Region: 1 - 403 Aligned: 401 Modelled: 403 Confidence: 100.0% Identity: 13% PDB header:membrane protein Chain: A: PDB Molecule:peptide abc transporter permease; PDBTitle: crystal structure of a pot family transporter in complex with2 thioalcohol conjugated peptide. Phyre2 PDB 1pv7 chain B Region: 11 - 416 Aligned: 405 Modelled: 406 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: B: PDB Molecule:lactose permease; PDBTitle: crystal structure of lactose permease with tdg Phyre2 PDB 6gs7 chain A Region: 9 - 403 Aligned: 395 Modelled: 395 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:dipeptide and tripeptide permease a; PDBTitle: crystal structure of peptide transporter dtpa-nanobody in glycine2 buffer Phyre2 PDB 4iky chain A Region: 3 - 407 Aligned: 404 Modelled: 405 Confidence: 100.0% Identity: 18% PDB header:transport protein Chain: A: PDB Molecule:di-tripeptide abc transporter (permease); PDBTitle: crystal structure of peptide transporter pot (e310q mutant) in complex2 with sulfate Phyre2 PDB 4aps chain B Region: 11 - 398 Aligned: 386 Modelled: 388 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: B: PDB Molecule:di-or tripeptide h+ symporter; PDBTitle: crystal structure of a pot family peptide transporter in an inward2 open conformation. Phyre2 PDB 4cl5 chain B Region: 3 - 408 Aligned: 406 Modelled: 406 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: B: PDB Molecule:nitrate transporter 1.1; PDBTitle: crystal structure of the nitrate transporter nrt1.1 from2 arabidopsis thaliana in complex with nitrate. Phyre2 PDB 4zp0 chain A Region: 5 - 400 Aligned: 389 Modelled: 396 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:multidrug transporter mdfa; PDBTitle: crystal structure of e. coli multidrug transporter mdfa in complex2 with deoxycholate Phyre2 PDB 1pw4 chain A Region: 2 - 412 Aligned: 409 Modelled: 411 Confidence: 100.0% Identity: 10% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: Glycerol-3-phosphate transporter Phyre2 PDB 4w6v chain A Region: 3 - 400 Aligned: 398 Modelled: 398 Confidence: 100.0% Identity: 16% PDB header:transport protein Chain: A: PDB Molecule:di-/tripeptide transporter; PDBTitle: crystal structure of a peptide transporter from yersinia2 enterocolitica at 3 a resolution Phyre2 PDB 6ei3 chain A Region: 11 - 412 Aligned: 402 Modelled: 402 Confidence: 100.0% Identity: 20% PDB header:membrane protein Chain: A: PDB Molecule:proton-dependent oligopeptide transporter family protein; PDBTitle: crystal structure of auto inhibited pot family peptide transporter Phyre2 PDB 4lds chain B Region: 14 - 404 Aligned: 389 Modelled: 391 Confidence: 100.0% Identity: 15% PDB header:transport protein, membrane protein Chain: B: PDB Molecule:bicyclomycin resistance protein tcab; PDBTitle: the inward-facing structure of the glucose transporter from2 staphylococcus epidermidis Phyre2 PDB 6g9x chain B Region: 11 - 404 Aligned: 367 Modelled: 378 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: B: PDB Molecule:major facilitator superfamily mfs_1; PDBTitle: crystal structure of a mfs transporter at 2.54 angstroem resolution Phyre2 PDB 2gfp chain A Region: 14 - 390 Aligned: 367 Modelled: 371 Confidence: 100.0% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein d; PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli Phyre2 PDB 5ayn chain A Region: 12 - 400 Aligned: 383 Modelled: 389 Confidence: 100.0% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 39 (iron-regulated transporter); PDBTitle: crystal structure of a bacterial homologue of iron transporter2 ferroportin in outward-facing state Phyre2 PDB 4q65 chain A Region: 9 - 398 Aligned: 385 Modelled: 390 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:dipeptide permease d; PDBTitle: structure of the e. coli peptide transporter ybgh Phyre2 PDB 4j05 chain A Region: 12 - 416 Aligned: 403 Modelled: 405 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:phosphate transporter; PDBTitle: crystal structure of a eukaryotic phosphate transporter Phyre2 PDB 4iu8 chain A Region: 3 - 399 Aligned: 397 Modelled: 396 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:nitrite extrusion protein 2; PDBTitle: crystal structure of a membrane transporter (selenomethionine2 derivative) Phyre2 1 c3wdoA_ 2 c6e9oA_ 3 d1pv7a_ 4 c6exsA_ 5 c1pv7B_ 6 c6gs7A_ 7 c4ikyA_ 8 c4apsB_ 9 c4cl5B_ 10 c4zp0A_ 11 d1pw4a_ 12 c4w6vA_ 13 c6ei3A_ 14 c4ldsB_ 15 c6g9xB_ 16 c2gfpA_ 17 c5aynA_ 18 c4q65A_ 19 c4j05A_ 20 c4iu8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44