1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	N	D	Q	R	D	Q	A	V	P	W	A	T	G	L	A	V	A	G	F	V	A	A	V	I	A	V	A	V	V	V	L	S	L	G	L	I	R	V	H	P	L	L	A	V	G	L	N	I	V	A	V	S	G	L	A	P	T	L	W
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?	?																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.
Sequence		G	W	R	R	T	P	V	L	R	W	F	V	L	G	A	A	V	G	V	A	G	A	W	L	A	L	L	A	L	T	L	G	D	G
Secondary structure
SS confidence
Disorder																																?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 84%) Beta strand ( 0%) TM helix ( 62%) (View membrane topology prediction)

Rank Aligned region

PDB 1v0d chain A Region: 3 - 15 Aligned: 13 Modelled: 13 Confidence: 26.5% Identity: 38% PDB header:hydrolase Chain: A: PDB Molecule:dna fragmentation factor 40 kda subunit; PDBTitle: crystal structure of caspase-activated dnase (cad) Phyre2 PDB 1v0d chain A Region: 3 - 15 Aligned: 13 Modelled: 13 Confidence: 26.5% Identity: 38% Fold: His-Me finger endonucleases Superfamily: His-Me finger endonucleases Family: Caspase-activated DNase, CAD (DffB, DFF40) Phyre2 PDB 1z8y chain L Region: 10 - 38 Aligned: 29 Modelled: 29 Confidence: 23.1% Identity: 48% PDB header:virus Chain: L: PDB Molecule:spike glycoprotein e2; PDBTitle: mapping the e2 glycoprotein of alphaviruses Phyre2 PDB 1z8y chain J Region: 10 - 38 Aligned: 29 Modelled: 29 Confidence: 23.1% Identity: 48% PDB header:virus Chain: J: PDB Molecule:spike glycoprotein e2; PDBTitle: mapping the e2 glycoprotein of alphaviruses Phyre2 PDB 1z8y chain N Region: 10 - 38 Aligned: 29 Modelled: 29 Confidence: 23.1% Identity: 48% PDB header:virus Chain: N: PDB Molecule:spike glycoprotein e2; PDBTitle: mapping the e2 glycoprotein of alphaviruses Phyre2 PDB 1z8y chain P Region: 10 - 38 Aligned: 29 Modelled: 29 Confidence: 23.1% Identity: 48% PDB header:virus Chain: P: PDB Molecule:spike glycoprotein e2; PDBTitle: mapping the e2 glycoprotein of alphaviruses Phyre2 PDB 1m57 chain H Region: 6 - 64 Aligned: 52 Modelled: 59 Confidence: 21.4% Identity: 19% PDB header:oxidoreductase Chain: H: PDB Molecule:cytochrome c oxidase; PDBTitle: structure of cytochrome c oxidase from rhodobacter2 sphaeroides (eq(i-286) mutant)) Phyre2 PDB 6hu9 chain N Region: 6 - 64 Aligned: 52 Modelled: 59 Confidence: 9.4% Identity: 13% PDB header:oxidoreductase/electron transport Chain: N: PDB Molecule:cytochrome b; PDBTitle: iii2-iv2 mitochondrial respiratory supercomplex from s. cerevisiae Phyre2 PDB 5tfy chain J Region: 12 - 31 Aligned: 20 Modelled: 20 Confidence: 7.7% Identity: 35% PDB header:cell adhesion Chain: J: PDB Molecule:flagellin; PDBTitle: the archaeal flagellum of methanospirillum hungatei strain jf1. Phyre2 PDB 2rng chain A Region: 67 - 82 Aligned: 16 Modelled: 16 Confidence: 6.8% Identity: 19% PDB header:antimicrobial protein Chain: A: PDB Molecule:big defensin; PDBTitle: solution structure of big defensin Phyre2 PDB 6f46 chain A Region: 69 - 81 Aligned: 13 Modelled: 13 Confidence: 6.5% Identity: 46% PDB header:apoptosis Chain: A: PDB Molecule:bcl-2-like protein 1; PDBTitle: structure of the transmembrane helix of bclxl in phospholipid2 nanodiscs Phyre2 PDB 1vjj chain A domain 4 Region: 53 - 69 Aligned: 16 Modelled: 17 Confidence: 6.4% Identity: 25% Fold: Cysteine proteinases Superfamily: Cysteine proteinases Family: Transglutaminase core Phyre2 PDB 1uou chain A domain 3 Region: 1 - 13 Aligned: 13 Modelled: 13 Confidence: 5.7% Identity: 23% Fold: alpha/beta-Hammerhead Superfamily: Pyrimidine nucleoside phosphorylase C-terminal domain Family: Pyrimidine nucleoside phosphorylase C-terminal domain Phyre2 PDB 5lnk chain W Region: 54 - 72 Aligned: 19 Modelled: 19 Confidence: 5.5% Identity: 32% PDB header:oxidoreductase Chain: W: PDB Molecule:mitochondrial complex i, sgdh subunit; PDBTitle: entire ovine respiratory complex i Phyre2 PDB 2tpt chain A domain 3 Region: 1 - 13 Aligned: 13 Modelled: 13 Confidence: 5.5% Identity: 38% Fold: alpha/beta-Hammerhead Superfamily: Pyrimidine nucleoside phosphorylase C-terminal domain Family: Pyrimidine nucleoside phosphorylase C-terminal domain Phyre2 1 c1v0dA_ 2 d1v0da_ 3 c1z8yL_ 4 c1z8yJ_ 5 c1z8yN_ 6 c1z8yP_ 7 c1m57H_ 8 c6hu9n_ 9 c5tfyJ_ 10 c2rngA_ 11 c6f46A_ 12 d1vjja4 13 d1uoua3 14 c5lnkW_ 15 d2tpta3