1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	I	N	V	E	P	A	L	S	P	H	L	V	V	D	D	A	A	S	A	I	D	F	Y	V	K	A	F	D	A	V	E	L	G	R	V	P	G	P	D	G	K	L	I	H	A	A	L	R	I	N	G	F	T	V	M	L	N	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	V	P	Q	M	C	G	G	K	S	M	T	P	T	S	L	G	G	T	P	V	T	I	H	L	T	V	T	D	V	D	A	K	F	Q	R	A	L	N	A	G	A	T	V	V	T	A	L	E	D	Q	L	W	G	D	R	Y	G	V	V
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
Sequence		A	D	P	F	G	H	H	W	S	L	G	Q	P	V	R	E	V	N	M	D	E	I	Q	A	A	M	S	S	Q	G	D	G
Secondary structure
SS confidence
Disorder																														?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 16%) Alpha helix ( 22%) Beta strand ( 37%)

Rank Aligned region

PDB 3itw chain A Region: 6 - 134 Aligned: 123 Modelled: 129 Confidence: 99.9% Identity: 27% PDB header:peptide binding protein Chain: A: PDB Molecule:protein tiox; PDBTitle: crystal structure of tiox from micromonospora sp. ml1 Phyre2 PDB 4nvs chain B Region: 9 - 148 Aligned: 132 Modelled: 129 Confidence: 99.9% Identity: 18% PDB header:unknown function Chain: B: PDB Molecule:putative enzyme, glyoxalase family; PDBTitle: crystal structure of the q18cp6_clod6 protein from glyoxalase family.2 northeast structural genomics consortium target cfr3 Phyre2 PDB 2zw7 chain A Region: 7 - 134 Aligned: 119 Modelled: 128 Confidence: 99.9% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:bleomycin acetyltransferase; PDBTitle: crystal structure of bleomycin n-acetyltransferase complexed2 with bleomycin a2 and coenzyme a Phyre2 PDB 1u6l chain A Region: 4 - 135 Aligned: 124 Modelled: 132 Confidence: 99.9% Identity: 19% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: 3-demethylubiquinone-9 3-methyltransferase Phyre2 PDB 3bt3 chain B Region: 10 - 134 Aligned: 120 Modelled: 125 Confidence: 99.9% Identity: 11% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:glyoxalase-related enzyme, arac type; PDBTitle: crystal structure of a glyoxalase-related enzyme from clostridium2 phytofermentans Phyre2 PDB 2q48 chain A Region: 8 - 132 Aligned: 113 Modelled: 125 Confidence: 99.9% Identity: 28% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:protein at5g48480; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at5g48480 Phyre2 PDB 1xy7 chain A Region: 8 - 132 Aligned: 113 Modelled: 125 Confidence: 99.9% Identity: 28% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Hypothetical protein At5g48480 Phyre2 PDB 3l20 chain A Region: 8 - 133 Aligned: 125 Modelled: 126 Confidence: 99.9% Identity: 22% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein from staphylococcus aureus Phyre2 PDB 4g6x chain A Region: 10 - 132 Aligned: 122 Modelled: 121 Confidence: 99.8% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of glyoxalase/bleomycin resistance protein from2 catenulispora acidiphila. Phyre2 PDB 3oms chain A Region: 8 - 132 Aligned: 119 Modelled: 125 Confidence: 99.8% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:phnb protein; PDBTitle: putative 3-demethylubiquinone-9 3-methyltransferase, phnb protein,2 from bacillus cereus. Phyre2 PDB 1u7i chain A Region: 8 - 131 Aligned: 118 Modelled: 124 Confidence: 99.8% Identity: 24% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: 3-demethylubiquinone-9 3-methyltransferase Phyre2 PDB 5umw chain A Region: 10 - 133 Aligned: 123 Modelled: 124 Confidence: 99.8% Identity: 18% PDB header:tiancimycin-binding protein Chain: A: PDB Molecule:glyoxalase/bleomycin resisance protein/dioxygenase; PDBTitle: crystal structure of tnms2, an antibiotic binding protein from2 streptomyces sp. cb03234 Phyre2 PDB 2rk9 chain B Region: 8 - 134 Aligned: 111 Modelled: 127 Confidence: 99.8% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: the crystal structure of a glyoxalase/bleomycin resistance2 protein/dioxygenase superfamily member from vibrio splendidus 12b01 Phyre2 PDB 3r6a chain B Region: 8 - 135 Aligned: 114 Modelled: 115 Confidence: 99.8% Identity: 15% PDB header:isomerase, lyase Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein (hypothetical protein2 mm_3218) from methanosarcina mazei. Phyre2 PDB 3m2o chain B Region: 6 - 132 Aligned: 117 Modelled: 127 Confidence: 99.8% Identity: 19% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:glyoxalase/bleomycin resistance protein; PDBTitle: crystal structure of a putative glyoxalase/bleomycin resistance2 protein from rhodopseudomonas palustris cga009 Phyre2 PDB 3fcd chain B Region: 8 - 136 Aligned: 107 Modelled: 113 Confidence: 99.8% Identity: 23% PDB header:lyase Chain: B: PDB Molecule:lyase; PDBTitle: crystal structure of a putative glyoxalase from an2 environmental bacteria Phyre2 PDB 1qip chain A Region: 10 - 135 Aligned: 125 Modelled: 126 Confidence: 99.8% Identity: 18% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Glyoxalase I (lactoylglutathione lyase) Phyre2 PDB 2pjs chain A domain 1 Region: 8 - 130 Aligned: 108 Modelled: 108 Confidence: 99.8% Identity: 19% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Antibiotic resistance proteins Phyre2 PDB 2r6u chain B Region: 5 - 135 Aligned: 122 Modelled: 131 Confidence: 99.8% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of gene product rha04853 from rhodococcus sp. rha1 Phyre2 PDB 4hc5 chain A Region: 2 - 132 Aligned: 125 Modelled: 131 Confidence: 99.8% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:glyoxalase/bleomycin resistance protein/dioxygenase; PDBTitle: crystal structure of member of glyoxalase/bleomycin resistance2 protein/dioxygenase superfamily from sphaerobacter thermophilus dsm3 20745 Phyre2 1 c3itwA_ 2 c4nvsB_ 3 c2zw7A_ 4 d1u6la_ 5 c3bt3B_ 6 c2q48A_ 7 d1xy7a_ 8 c3l20A_ 9 c4g6xA_ 10 c3omsA_ 11 d1u7ia_ 12 c5umwA_ 13 c2rk9B_ 14 c3r6aB_ 15 c3m2oB_ 16 c3fcdB_ 17 d1qipa_ 18 d2pjsa1 19 c2r6uB_ 20 c4hc5A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176