1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	T	E	P	L	T	K	P	A	L	V	A	V	D	M	R	P	A	R	R	G	E	R	L	F	K	L	A	A	S	A	A	G	S	T	I	V	I	A	I	L	L	I	A	I	F	L	L	V	R	A	V	P	S	L	R	A	N	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	N	F	F	T	S	T	Q	F	D	T	S	D	D	E	Q	L	A	F	G	V	R	D	L	F	M	V	T	A	L	S	S	I	T	A	L	V	L	A	V	P	V	A	V	G	I	A	V	F	L	T	H	Y	A	P	R	R	L	S	R
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	F	G	A	M	V	D	L	L	A	A	V	P	S	I	I	F	G	L	W	G	I	F	V	L	A	P	K	L	E	P	I	A	R	F	L	N	R	N	L	G	W	L	F	L	F	K	Q	G	N	V	S	L	A	G	G	G	T	I	F
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	A	G	I	V	L	S	V	M	I	L	P	I	V	T	S	I	S	R	E	V	F	R	Q	T	P	L	I	Q	I	E	A	A	L	A	L	G	A	T	K	W	E	V	V	R	M	T	V	L	P	Y	G	R	S	G	V	V	A	A	S
Secondary structure
SS confidence
Disorder																									?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		M	L	G	L	G	R	A	L	G	E	T	V	A	V	L	V	I	L	R	S	A	A	R	P	G	T	W	S	L	F	D	G	G	Y	T	F	A	S	K	I	A	S	A	A	S	E	F	S	E	P	L	P	T	G	A	Y	I	S	A	G
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?	?	?	?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.
Sequence		F	A	L	F	V	L	T	F	L	V	N	A	A	A	R	A	I	A	G	G	K	V	N	G
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 77%) Beta strand ( 0%) TM helix ( 50%) (View membrane topology prediction)

Rank Aligned region

PDB 3fh6 chain F Region: 21 - 321 Aligned: 296 Modelled: 301 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain I Region: 14 - 323 Aligned: 286 Modelled: 302 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 57 - 313 Aligned: 251 Modelled: 257 Confidence: 100.0% Identity: 15% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain F domain 2 Region: 69 - 313 Aligned: 239 Modelled: 245 Confidence: 100.0% Identity: 13% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 12 - 322 Aligned: 281 Modelled: 282 Confidence: 100.0% Identity: 14% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain G domain 1 Region: 21 - 324 Aligned: 272 Modelled: 284 Confidence: 100.0% Identity: 14% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 23 - 319 Aligned: 251 Modelled: 268 Confidence: 100.0% Identity: 19% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 23 - 319 Aligned: 251 Modelled: 268 Confidence: 100.0% Identity: 19% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain C domain 1 Region: 29 - 315 Aligned: 247 Modelled: 264 Confidence: 100.0% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 29 - 315 Aligned: 247 Modelled: 264 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 4ymu chain C Region: 68 - 321 Aligned: 213 Modelled: 230 Confidence: 100.0% Identity: 16% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 81 - 313 Aligned: 192 Modelled: 195 Confidence: 99.9% Identity: 23% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5kbu chain A Region: 83 - 232 Aligned: 85 Modelled: 99 Confidence: 58.8% Identity: 27% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2m8g chain X Region: 197 - 227 Aligned: 31 Modelled: 31 Confidence: 28.1% Identity: 23% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 1umq chain A Region: 197 - 227 Aligned: 31 Modelled: 31 Confidence: 22.1% Identity: 13% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1umq chain A Region: 197 - 227 Aligned: 31 Modelled: 31 Confidence: 22.1% Identity: 13% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 6gcs chain 6 Region: 10 - 115 Aligned: 106 Modelled: 106 Confidence: 18.5% Identity: 9% PDB header:oxidoreductase Chain: 6: PDB Molecule:nd6 subunit (nu6m); PDBTitle: cryo-em structure of respiratory complex i from yarrowia lipolytica Phyre2 PDB 4l5e chain A Region: 197 - 227 Aligned: 31 Modelled: 31 Confidence: 18.1% Identity: 13% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1ntc chain A Region: 196 - 227 Aligned: 32 Modelled: 32 Confidence: 17.7% Identity: 22% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 2mom chain B Region: 91 - 118 Aligned: 28 Modelled: 28 Confidence: 14.8% Identity: 18% PDB header:membrane protein Chain: B: PDB Molecule:lysosome-associated membrane glycoprotein 2; PDBTitle: structural insights of tm domain of lamp-2a in dpc micelles Phyre2 1 c3fh6F_ 2 c4tqvI_ 3 c2r6gF_ 4 d2r6gf2 5 c4tqvJ_ 6 d2r6gg1 7 c2onkC_ 8 d2onkc1 9 d3d31c1 10 c3d31D_ 11 c4ymuC_ 12 d3dhwa1 13 c5kbuA_ 14 c2m8gX_ 15 c1umqA_ 16 d1umqa_ 17 c6gcs6_ 18 c4l5eA_ 19 d1ntca_ 20 c2momB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41