1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	I	E	A	L	D	Q	P	V	K	P	V	V	F	R	P	L	T	L	R	R	R	I	K	N	S	V	A	T	T	F	F	F	T	S	F	V	V	A	L	I	P	L	V	W	L	L	W	V	V	I	A	R	G	W	F	A	V	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	S	G	W	W	T	H	S	L	R	G	V	L	P	E	Q	F	A	G	G	V	Y	H	A	L	Y	G	T	L	V	Q	A	G	V	A	A	V	L	A	V	P	L	G	L	M	T	A	V	Y	L	V	E	Y	G	T	G	R	M	S	R
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	T	T	F	T	V	D	V	L	A	G	V	P	S	I	V	A	A	L	F	V	F	S	L	W	I	A	T	L	G	F	Q	Q	S	A	F	A	V	A	L	A	L	V	L	L	M	L	P	V	V	V	R	A	G	E	E	M	L	R	L
Secondary structure
SS confidence
Disorder												?																		?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	P	D	E	L	R	E	A	S	Y	A	L	G	V	P	K	W	K	T	I	V	R	I	V	A	P	I	A	M	P	G	I	V	S	G	I	L	L	S	I	A	R	V	V	G	E	T	A	P	V	L	V	L	V	G	Y	S	H	S	I
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		N	L	D	V	F	H	G	N	M	A	S	L	P	L	L	I	Y	T	E	L	T	N	P	E	H	A	G	F	L	R	V	W	G	A	A	L	T	L	I	I	V	V	A	T	I	N	L	A	A	A	M	I	R	F	V	A	T	R	R	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?														?	?	?	?																															?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 77%) Beta strand ( 0%) TM helix ( 51%) (View membrane topology prediction)

Rank Aligned region

PDB 4tqv chain I Region: 17 - 298 Aligned: 267 Modelled: 282 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3fh6 chain F Region: 20 - 297 Aligned: 278 Modelled: 278 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain J Region: 19 - 298 Aligned: 274 Modelled: 280 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 55 - 288 Aligned: 233 Modelled: 234 Confidence: 100.0% Identity: 16% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain G domain 1 Region: 20 - 299 Aligned: 270 Modelled: 280 Confidence: 100.0% Identity: 13% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 2 Region: 69 - 288 Aligned: 219 Modelled: 220 Confidence: 100.0% Identity: 16% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C domain 1 Region: 26 - 292 Aligned: 241 Modelled: 267 Confidence: 100.0% Identity: 19% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 26 - 292 Aligned: 241 Modelled: 267 Confidence: 100.0% Identity: 19% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 3d31 chain C domain 1 Region: 28 - 290 Aligned: 234 Modelled: 238 Confidence: 100.0% Identity: 22% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 28 - 290 Aligned: 234 Modelled: 238 Confidence: 100.0% Identity: 22% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 4ymu chain C Region: 68 - 297 Aligned: 214 Modelled: 214 Confidence: 100.0% Identity: 15% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 81 - 290 Aligned: 194 Modelled: 194 Confidence: 100.0% Identity: 21% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5kbu chain A Region: 87 - 208 Aligned: 85 Modelled: 85 Confidence: 87.6% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2m8g chain X Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 38.7% Identity: 23% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 2hx6 chain A Region: 172 - 197 Aligned: 26 Modelled: 26 Confidence: 36.9% Identity: 42% PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease; PDBTitle: solution structure analysis of the phage t42 endoribonuclease regb Phyre2 PDB 1umq chain A Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 28.1% Identity: 6% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 1umq chain A Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 28.1% Identity: 6% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1ntc chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 27.7% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 4l5e chain A Region: 172 - 203 Aligned: 32 Modelled: 32 Confidence: 26.2% Identity: 25% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 PDB 1fip chain A Region: 173 - 203 Aligned: 31 Modelled: 31 Confidence: 21.1% Identity: 6% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 1 c4tqvI_ 2 c3fh6F_ 3 c4tqvJ_ 4 c2r6gF_ 5 d2r6gg1 6 d2r6gf2 7 d2onkc1 8 c2onkC_ 9 d3d31c1 10 c3d31D_ 11 c4ymuC_ 12 d3dhwa1 13 c5kbuA_ 14 c2m8gX_ 15 c2hx6A_ 16 c1umqA_ 17 d1umqa_ 18 d1ntca_ 19 c4l5eA_ 20 d1fipa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40