1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	E	S	A	E	S	G	S	R	Q	L	P	A	M	S	P	P	R	R	S	V	A	Y	R	R	K	I	V	D	A	L	W	W	A	A	C	V	C	C	L	A	V	V	I	T	P	T	L	W	M	L	I	G	V	V	S	R	A	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	V	F	H	W	S	V	L	V	Q	D	S	Q	G	N	G	G	G	L	R	N	A	I	I	G	T	A	V	L	A	I	G	V	I	L	V	G	G	T	V	S	V	L	T	G	I	Y	L	S	E	F	A	T	G	K	T	R	S	I	L
Secondary structure
SS confidence
Disorder										?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	G	A	Y	E	V	L	S	G	I	P	S	I	V	L	G	Y	V	G	Y	L	A	L	V	V	Y	F	D	W	G	F	S	L	A	A	G	V	L	V	L	S	V	M	S	I	P	Y	I	A	K	A	T	E	S	A	L	A	Q	V	P
Secondary structure
SS confidence
Disorder										?																			?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	S	Y	R	E	A	A	E	A	L	G	L	P	A	G	W	A	L	R	K	I	V	L	K	T	A	M	P	G	I	V	T	G	M	L	V	A	L	A	L	A	I	G	E	T	A	P	L	L	Y	T	A	G	W	S	N	S	P	P	T
Secondary structure
SS confidence
Disorder																																																							?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	Q	L	T	D	S	P	V	G	Y	L	T	Y	P	I	W	T	F	Y	N	Q	P	S	K	S	A	Q	D	L	S	Y	D	A	A	L	L	L	I	V	F	L	L	L	L	I	F	I	G	R	L	I	N	W	L	S	R	R	R	W	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?										?	?	?	?	?	?	?																																?	?	?	?
Disorder confidence
		.
Sequence		V
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 76%) Beta strand ( 0%) TM helix ( 50%) (View membrane topology prediction)

Rank Aligned region

PDB 4tqv chain I Region: 21 - 297 Aligned: 267 Modelled: 277 Confidence: 100.0% Identity: 12% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3fh6 chain F Region: 24 - 297 Aligned: 274 Modelled: 274 Confidence: 100.0% Identity: 11% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 2r6g chain F Region: 64 - 287 Aligned: 223 Modelled: 224 Confidence: 100.0% Identity: 13% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 4tqv chain J Region: 22 - 297 Aligned: 259 Modelled: 276 Confidence: 100.0% Identity: 9% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F domain 2 Region: 67 - 287 Aligned: 220 Modelled: 221 Confidence: 100.0% Identity: 13% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 26 - 291 Aligned: 241 Modelled: 253 Confidence: 100.0% Identity: 17% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 26 - 291 Aligned: 241 Modelled: 253 Confidence: 100.0% Identity: 17% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain G domain 1 Region: 24 - 297 Aligned: 262 Modelled: 274 Confidence: 100.0% Identity: 13% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4ymu chain C Region: 65 - 296 Aligned: 215 Modelled: 215 Confidence: 100.0% Identity: 17% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3d31 chain D Region: 32 - 289 Aligned: 234 Modelled: 245 Confidence: 100.0% Identity: 18% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 3d31 chain C domain 1 Region: 32 - 289 Aligned: 234 Modelled: 245 Confidence: 100.0% Identity: 18% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3dhw chain A domain 1 Region: 79 - 289 Aligned: 194 Modelled: 194 Confidence: 99.9% Identity: 23% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F domain 1 Region: 25 - 62 Aligned: 38 Modelled: 38 Confidence: 50.4% Identity: 8% Fold: MalF N-terminal region-like Superfamily: MalF N-terminal region-like Family: MalF N-terminal region-like Phyre2 PDB 5kbu chain A Region: 120 - 206 Aligned: 83 Modelled: 87 Confidence: 38.2% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2m8g chain X Region: 171 - 201 Aligned: 31 Modelled: 31 Confidence: 32.4% Identity: 23% PDB header:transcription Chain: X: PDB Molecule:transcriptional regulator; PDBTitle: structure, function, and tethering of dna-binding domains in 542 transcriptional activators Phyre2 PDB 1umq chain A Region: 171 - 201 Aligned: 31 Modelled: 31 Confidence: 28.4% Identity: 13% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 1umq chain A Region: 171 - 201 Aligned: 31 Modelled: 31 Confidence: 28.4% Identity: 13% PDB header:dna-binding protein Chain: A: PDB Molecule:photosynthetic apparatus regulatory protein; PDBTitle: solution structure and dna binding of the effector domain2 from the global regulator prra(rega) from r. sphaeroides:3 insights into dna binding specificity Phyre2 PDB 2hx6 chain A Region: 170 - 195 Aligned: 26 Modelled: 26 Confidence: 28.4% Identity: 31% PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease; PDBTitle: solution structure analysis of the phage t42 endoribonuclease regb Phyre2 PDB 1ntc chain A Region: 170 - 201 Aligned: 32 Modelled: 32 Confidence: 27.7% Identity: 28% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: FIS-like Phyre2 PDB 4l5e chain A Region: 170 - 201 Aligned: 32 Modelled: 32 Confidence: 25.6% Identity: 22% PDB header:protein binding Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of a. aeolicus ntrc1 dna binding domain Phyre2 1 c4tqvI_ 2 c3fh6F_ 3 c2r6gF_ 4 c4tqvJ_ 5 d2r6gf2 6 c2onkC_ 7 d2onkc1 8 d2r6gg1 9 c4ymuC_ 10 c3d31D_ 11 d3d31c1 12 d3dhwa1 13 d2r6gf1 14 c5kbuA_ 15 c2m8gX_ 16 d1umqa_ 17 c1umqA_ 18 c2hx6A_ 19 d1ntca_ 20 c4l5eA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52