1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	A	I	W	T	G	S	I	A	F	G	L	V	N	V	P	V	K	V	Y	S	A	T	A	D	H	D	I	R	F	H	Q	V	H	A	K	D	N	G	R	I	R	Y	K	R	V	C	E	A	C	G	E	V	V	D	Y	R	D	L
Secondary structure
SS confidence
Disorder		?	?	?	?																																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	R	A	Y	E	S	G	D	G	Q	M	V	A	I	T	D	D	D	I	A	S	L	P	E	E	R	S	R	E	I	E	V	L	E	F	V	P	A	A	D	V	D	P	M	M	F	D	R	S	Y	F	L	E	P	D	S	K	S	S	K
Secondary structure
SS confidence
Disorder																									?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	Y	V	L	L	A	K	T	L	A	E	T	D	R	M	A	I	V	H	F	T	L	R	N	K	T	R	L	A	A	L	R	V	K	D	F	G	K	R	E	V	M	M	V	H	T	L	L	W	P	D	E	I	R	D	P	D	F	P	V
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	D	Q	K	V	E	I	K	P	A	E	L	K	M	A	G	Q	V	V	D	S	M	A	D	D	F	N	P	D	R	Y	H	D	T	Y	Q	E	Q	L	Q	E	L	I	D	T	K	L	E	G	G	Q	A	F	T	A	E	D	Q	P	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?													?	?	?	?	?	?	?							?														?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.
Sequence		L	L	D	E	P	E	D	V	S	D	L	L	A	K	L	E	A	S	V	K	A	R	S	K	A	N	S	N	V	P	T	P	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 22%) Alpha helix ( 27%) Beta strand ( 29%)

Rank Aligned region

PDB 1jey chain A domain 1 Region: 2 - 259 Aligned: 254 Modelled: 258 Confidence: 100.0% Identity: 14% Fold: SPOC domain-like Superfamily: SPOC domain-like Family: Ku70 subunit middle domain Phyre2 PDB 1jey chain B domain 1 Region: 5 - 272 Aligned: 267 Modelled: 268 Confidence: 100.0% Identity: 15% Fold: SPOC domain-like Superfamily: SPOC domain-like Family: Ku80 subunit middle domain Phyre2 PDB 1jeq chain A Region: 2 - 270 Aligned: 265 Modelled: 269 Confidence: 100.0% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:ku70; PDBTitle: crystal structure of the ku heterodimer Phyre2 PDB 1jey chain B Region: 2 - 273 Aligned: 271 Modelled: 272 Confidence: 100.0% Identity: 14% PDB header:dna binding protein/dna Chain: B: PDB Molecule:ku80; PDBTitle: crystal structure of the ku heterodimer bound to dna Phyre2 PDB 5y58 chain E Region: 2 - 238 Aligned: 235 Modelled: 237 Confidence: 100.0% Identity: 17% PDB header:rna binding protein Chain: E: PDB Molecule:atp-dependent dna helicase ii subunit 1; PDBTitle: crystal structure of ku70/80 and tlc1 Phyre2 PDB 5y58 chain D Region: 1 - 273 Aligned: 271 Modelled: 273 Confidence: 100.0% Identity: 17% PDB header:rna binding protein Chain: D: PDB Molecule:atp-dependent dna helicase ii subunit 2; PDBTitle: crystal structure of ku70/80 and tlc1 Phyre2 PDB 4gcv chain D Region: 26 - 60 Aligned: 35 Modelled: 35 Confidence: 55.4% Identity: 14% PDB header:transcription Chain: D: PDB Molecule:putative transcription protein; PDBTitle: structure of a putative transcription factor (pa1374)from pseudomonas2 aeruginosa Phyre2 PDB 2f2e chain A domain 1 Region: 23 - 61 Aligned: 39 Modelled: 39 Confidence: 55.0% Identity: 13% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: HxlR-like Phyre2 PDB 2jwl chain B Region: 216 - 258 Aligned: 43 Modelled: 43 Confidence: 34.8% Identity: 14% PDB header:membrane protein Chain: B: PDB Molecule:protein tolr; PDBTitle: solution structure of periplasmic domain of tolr from h.2 influenzae with saxs data Phyre2 PDB 4xjc chain D Region: 5 - 38 Aligned: 34 Modelled: 34 Confidence: 33.5% Identity: 21% PDB header:hydrolase Chain: D: PDB Molecule:deoxycytidine triphosphate deaminase; PDBTitle: dctp deaminase-dutpase from bacillus halodurans Phyre2 PDB 2r9q chain D Region: 5 - 32 Aligned: 28 Modelled: 28 Confidence: 33.3% Identity: 25% PDB header:hydrolase Chain: D: PDB Molecule:2'-deoxycytidine 5'-triphosphate deaminase; PDBTitle: crystal structure of 2'-deoxycytidine 5'-triphosphate deaminase from2 agrobacterium tumefaciens Phyre2 PDB 5kxf chain A Region: 87 - 170 Aligned: 81 Modelled: 84 Confidence: 22.9% Identity: 17% PDB header:rna binding protein Chain: A: PDB Molecule:flowering time control protein fpa; PDBTitle: crystal structure of the spoc domain of the arabidopsis flowering2 regulator fpa Phyre2 PDB 3mhs chain E Region: 46 - 61 Aligned: 16 Modelled: 16 Confidence: 22.8% Identity: 38% PDB header:hydrolase/transcription regulator/protei Chain: E: PDB Molecule:saga-associated factor 73; PDBTitle: structure of the saga ubp8/sgf11/sus1/sgf73 dub module bound to2 ubiquitin aldehyde Phyre2 PDB 4dn7 chain B Region: 169 - 230 Aligned: 59 Modelled: 61 Confidence: 20.8% Identity: 17% PDB header:transport protein Chain: B: PDB Molecule:abc transporter, atp-binding protein; PDBTitle: crystal structure of putative abc transporter, atp-binding protein2 from methanosarcina mazei go1 Phyre2 PDB 1f8v chain A Region: 4 - 66 Aligned: 61 Modelled: 63 Confidence: 18.7% Identity: 13% PDB header:virus/rna Chain: A: PDB Molecule:mature capsid protein beta; PDBTitle: the structure of pariacoto virus reveals a dodecahedral cage of duplex2 rna Phyre2 PDB 2qxx chain A Region: 5 - 41 Aligned: 37 Modelled: 37 Confidence: 16.3% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:deoxycytidine triphosphate deaminase; PDBTitle: bifunctional dctp deaminase: dutpase from mycobacterium tuberculosis2 in complex with dttp Phyre2 PDB 2lo3 chain A Region: 46 - 61 Aligned: 16 Modelled: 16 Confidence: 15.7% Identity: 38% PDB header:transcription Chain: A: PDB Molecule:saga-associated factor 73; PDBTitle: solution structure of sgf73(59-102) zinc finger domain Phyre2 PDB 2cw9 chain A domain 1 Region: 189 - 266 Aligned: 69 Modelled: 78 Confidence: 15.5% Identity: 12% Fold: Cystatin-like Superfamily: NTF2-like Family: TIM44-like Phyre2 PDB 5by4 chain A Region: 216 - 257 Aligned: 42 Modelled: 42 Confidence: 13.8% Identity: 10% PDB header:protein transport Chain: A: PDB Molecule:protein tolr; PDBTitle: structure and function of the escherichia coli tol-pal stator protein2 tolr Phyre2 PDB 1ow1 chain A Region: 3 - 46 Aligned: 44 Modelled: 44 Confidence: 12.2% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:smart/hdac1 associated repressor protein; PDBTitle: crystal structure of the spoc domain of the human2 transcriptional corepressor, sharp. Phyre2 1 d1jeya1 2 d1jeyb1 3 c1jeqA_ 4 c1jeyB_ 5 c5y58E_ 6 c5y58D_ 7 c4gcvD_ 8 d2f2ea1 9 c2jwlB_ 10 c4xjcD_ 11 c2r9qD_ 12 c5kxfA_ 13 c3mhsE_ 14 c4dn7B_ 15 c1f8vA_ 16 c2qxxA_ 17 c2lo3A_ 18 d2cw9a1 19 c5by4A_ 20 c1ow1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64