1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	R	V	P	S	Q	W	M	I	S	S	R	V	T	V	A	W	N	I	V	G	Y	L	V	Y	A	A	L	A	F	V	G	G	F	A	V	W	F	S	L	F	F	A	M	A	T	D	G	C	H	D	S	A	C	D	A	S	Y	H	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.
Sequence		F	P	A	M	V	T	M	W	I	G	V	G	A	V	L	L	L	T	L	V	V	M	V	R	N	S	S	R	G	N	V	V	I	G	W	P	F	V	G	L	L	A	L	G	L	V	Y	V	A	A	D	A	V	L	H
Secondary structure
SS confidence
Disorder																																																						?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 10%) Alpha helix ( 83%) Beta strand ( 4%) TM helix ( 56%) (View membrane topology prediction)

Rank Aligned region

PDB 5gpd chain A Region: 33 - 70 Aligned: 35 Modelled: 38 Confidence: 39.4% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:sterol regulatory element-binding protein 1; PDBTitle: crystal structure of the binding domain of srebp from fission yeast Phyre2 PDB 3kdp chain G Region: 21 - 39 Aligned: 19 Modelled: 19 Confidence: 26.6% Identity: 47% PDB header:hydrolase Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 3kdp chain H Region: 21 - 39 Aligned: 19 Modelled: 19 Confidence: 26.6% Identity: 47% PDB header:hydrolase Chain: H: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of the sodium-potassium pump Phyre2 PDB 2kvx chain A Region: 48 - 58 Aligned: 11 Modelled: 11 Confidence: 24.2% Identity: 55% PDB header:plant protein Chain: A: PDB Molecule:kalata-b12; PDBTitle: solution structure of kalata b12 Phyre2 PDB 4hqj chain G Region: 21 - 39 Aligned: 19 Modelled: 19 Confidence: 23.6% Identity: 47% PDB header:hydrolase/transport protein Chain: G: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of na+,k+-atpase in the na+-bound state Phyre2 PDB 6hra chain D Region: 13 - 26 Aligned: 14 Modelled: 14 Confidence: 23.1% Identity: 50% PDB header:membrane protein Chain: D: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: cryo-em structure of the kdpfabc complex in an e1 outward-facing state2 (state 1) Phyre2 PDB 4hqj chain E Region: 21 - 39 Aligned: 19 Modelled: 19 Confidence: 22.0% Identity: 47% PDB header:hydrolase/transport protein Chain: E: PDB Molecule:na+/k+ atpase gamma subunit transcript variant a; PDBTitle: crystal structure of na+,k+-atpase in the na+-bound state Phyre2 PDB 6hrb chain D Region: 13 - 28 Aligned: 16 Modelled: 16 Confidence: 18.1% Identity: 44% PDB header:membrane protein Chain: D: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: cryo-em structure of the kdpfabc complex in an e2 inward-facing state2 (state 2) Phyre2 PDB 5mrw chain D Region: 13 - 28 Aligned: 16 Modelled: 16 Confidence: 18.1% Identity: 44% PDB header:hydrolase Chain: D: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 5mrw chain H Region: 13 - 28 Aligned: 16 Modelled: 16 Confidence: 18.1% Identity: 44% PDB header:hydrolase Chain: H: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 5mrw chain L Region: 13 - 28 Aligned: 16 Modelled: 16 Confidence: 18.1% Identity: 44% PDB header:hydrolase Chain: L: PDB Molecule:potassium-transporting atpase kdpf subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 1j5j chain A Region: 51 - 62 Aligned: 12 Modelled: 12 Confidence: 15.5% Identity: 50% Fold: Knottins (small inhibitors, toxins, lectins) Superfamily: Scorpion toxin-like Family: Short-chain scorpion toxins Phyre2 PDB 6gcs chain 3 Region: 63 - 115 Aligned: 53 Modelled: 53 Confidence: 14.4% Identity: 23% PDB header:oxidoreductase Chain: 3: PDB Molecule:nd3 subunit (nu3m); PDBTitle: cryo-em structure of respiratory complex i from yarrowia lipolytica Phyre2 PDB 3ju6 chain A Region: 2 - 22 Aligned: 21 Modelled: 20 Confidence: 13.9% Identity: 38% PDB header:transferase Chain: A: PDB Molecule:arginine kinase; PDBTitle: crystal structure of dimeric arginine kinase in complex with2 amppnp and arginine Phyre2 PDB 3rko chain A Region: 63 - 115 Aligned: 53 Modelled: 53 Confidence: 13.9% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:nadh-quinone oxidoreductase subunit a; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 3rko chain E Region: 63 - 115 Aligned: 53 Modelled: 53 Confidence: 13.9% Identity: 28% PDB header:oxidoreductase Chain: E: PDB Molecule:nadh-quinone oxidoreductase subunit a; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 1m15 chain A domain 2 Region: 4 - 22 Aligned: 19 Modelled: 19 Confidence: 12.8% Identity: 37% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Guanido kinase catalytic domain Phyre2 PDB 1wco chain N Region: 45 - 60 Aligned: 16 Modelled: 16 Confidence: 12.6% Identity: 50% PDB header:peptide/antibiotic Chain: N: PDB Molecule:nisin z; PDBTitle: the solution structure of the nisin-lipid ii complex Phyre2 PDB 4he8 chain B Region: 63 - 114 Aligned: 52 Modelled: 52 Confidence: 12.4% Identity: 21% PDB header:oxidoreductase Chain: B: PDB Molecule:nadh-quinone oxidoreductase subunit 7; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 thermus thermophilus Phyre2 PDB 1qk1 chain A domain 2 Region: 4 - 22 Aligned: 19 Modelled: 19 Confidence: 12.2% Identity: 32% Fold: Glutamine synthetase/guanido kinase Superfamily: Glutamine synthetase/guanido kinase Family: Guanido kinase catalytic domain Phyre2 1 c5gpdA_ 2 c3kdpG_ 3 c3kdpH_ 4 c2kvxA_ 5 c4hqjG_ 6 c6hraD_ 7 c4hqjE_ 8 c6hrbD_ 9 c5mrwD_ 10 c5mrwH_ 11 c5mrwL_ 12 d1j5ja_ 13 c6gcs3_ 14 c3ju6A_ 15 c3rkoA_ 16 c3rkoE_ 17 d1m15a2 18 c1wcoN_ 19 c4he8B_ 20 d1qk1a2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42