1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	N	S	A	Q	R	D	A	R	N	S	R	D	E	S	A	R	A	S	D	T	D	R	I	Q	I	A	Q	L	L	A	Y	A	A	E	Q	G	R	L	Q	L	T	D	Y	E	D	R	L	A	R	A	Y	A	A	T	T	Y	Q	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	D	R	L	R	A	D	L	P	G	A	A	I	G	P	R	R	G	G	E	C	N	P	A	P	S	T	L	L	L	A	L	L	G	G	F	E	R	R	G	R	W	N	V	P	K	K	L	T	T	F	T	L	W	G	S	G	V	L	D
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?				?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	R	Y	A	D	F	T	S	T	E	V	D	I	R	A	Y	S	I	M	G	A	Q	T	I	L	L	P	P	E	V	N	V	E	I	H	G	H	R	V	M	G	G	F	D	R	K	V	V	G	E	G	T	R	G	V	P	T	V	R	I
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200
Sequence		R	G	F	S	L	W	G	D	V	G	I	K	R	K	P	R	K	P	R	K
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 29%) Alpha helix ( 22%) Beta strand ( 35%)

Rank Aligned region

PDB 4qrk chain A Region: 106 - 194 Aligned: 87 Modelled: 89 Confidence: 98.6% Identity: 21% PDB header:cell adhesion Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a putative cell adhesion protein (clospo_03726)2 from clostridium sporogenes atcc 15579 at 1.95 a resolution Phyre2 PDB 2pp4 chain A domain 1 Region: 23 - 65 Aligned: 43 Modelled: 43 Confidence: 55.8% Identity: 9% Fold: TAFH domain-like Superfamily: TAFH domain-like Family: TAFH domain-like Phyre2 PDB 2p12 chain A domain 1 Region: 28 - 55 Aligned: 28 Modelled: 28 Confidence: 41.2% Identity: 25% Fold: FomD barrel-like Superfamily: FomD-like Family: FomD-like Phyre2 PDB 2caz chain A domain 1 Region: 16 - 49 Aligned: 34 Modelled: 34 Confidence: 40.4% Identity: 15% Fold: Long alpha-hairpin Superfamily: Endosomal sorting complex assembly domain Family: VPS23 C-terminal domain Phyre2 PDB 2caz chain D Region: 16 - 49 Aligned: 34 Modelled: 34 Confidence: 40.0% Identity: 15% PDB header:protein transport Chain: D: PDB Molecule:suppressor protein stp22 of temperature-sensitive alpha- PDBTitle: escrt-i core Phyre2 PDB 2f6m chain A domain 1 Region: 16 - 49 Aligned: 34 Modelled: 34 Confidence: 39.8% Identity: 15% Fold: Long alpha-hairpin Superfamily: Endosomal sorting complex assembly domain Family: VPS23 C-terminal domain Phyre2 PDB 2p6v chain A domain 1 Region: 21 - 69 Aligned: 47 Modelled: 49 Confidence: 35.4% Identity: 21% Fold: TAFH domain-like Superfamily: TAFH domain-like Family: TAFH domain-like Phyre2 PDB 1pon chain B Region: 37 - 50 Aligned: 14 Modelled: 14 Confidence: 27.0% Identity: 14% PDB header:calcium-binding protein Chain: B: PDB Molecule:troponin c; PDBTitle: site iii-site iv troponin c heterodimer, nmr Phyre2 PDB 3i38 chain K Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 26.2% Identity: 14% PDB header:chaperone Chain: K: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 3i38 chain B Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 24.8% Identity: 14% PDB header:chaperone Chain: B: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 3i38 chain D Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 24.7% Identity: 14% PDB header:chaperone Chain: D: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 3i38 chain A Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 24.7% Identity: 14% PDB header:chaperone Chain: A: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 3i38 chain G Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 24.7% Identity: 14% PDB header:chaperone Chain: G: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 2p22 chain A Region: 19 - 45 Aligned: 27 Modelled: 27 Confidence: 22.8% Identity: 19% PDB header:transport protein Chain: A: PDB Molecule:suppressor protein stp22 of temperature-sensitive alpha- PDBTitle: structure of the yeast escrt-i heterotetramer core Phyre2 PDB 3i38 chain E Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 22.3% Identity: 14% PDB header:chaperone Chain: E: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 3i38 chain C Region: 112 - 151 Aligned: 37 Modelled: 40 Confidence: 22.3% Identity: 14% PDB header:chaperone Chain: C: PDB Molecule:putative chaperone dnaj; PDBTitle: structure of a putative chaperone protein dnaj from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 Phyre2 PDB 4ege chain A Region: 38 - 55 Aligned: 18 Modelled: 18 Confidence: 21.5% Identity: 50% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidase pepe; PDBTitle: crystal structure of dipeptidase pepe from mycobacterium ulcerans Phyre2 PDB 3e56 chain A Region: 23 - 38 Aligned: 16 Modelled: 16 Confidence: 21.4% Identity: 44% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: the 2.0 angstrom resolution crystal structure of npr1517, a putative2 heterocyst differentiation inhibitor from nostoc punctiforme Phyre2 PDB 2caz chain B domain 1 Region: 27 - 54 Aligned: 28 Modelled: 28 Confidence: 20.7% Identity: 11% Fold: Long alpha-hairpin Superfamily: Endosomal sorting complex assembly domain Family: VPS28 N-terminal domain Phyre2 PDB 2caz chain B Region: 27 - 54 Aligned: 28 Modelled: 28 Confidence: 20.7% Identity: 11% PDB header:protein transport Chain: B: PDB Molecule:vacuolar protein sorting-associated protein vps28; PDBTitle: escrt-i core Phyre2 1 c4qrkA_ 2 d2pp4a1 3 d2p12a1 4 d2caza1 5 c2cazD_ 6 d2f6ma1 7 d2p6va1 8 c1ponB_ 9 c3i38K_ 10 c3i38B_ 11 c3i38D_ 12 c3i38A_ 13 c3i38G_ 14 c2p22A_ 15 c3i38E_ 16 c3i38C_ 17 c4egeA_ 18 c3e56A_ 19 d2cazb1 20 c2cazB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99