Phyre 2 Results for RVBD0977_(PE_PGRS16)_1090377

Email	mdejesus@rockefeller.edu
Description	RVBD0977_(PE_PGRS16)_1090377_1093148
Date	Wed Jul 31 22:05:04 BST 2019
Unique Job ID	bc42aa0231215a79
Sequence	MSFVVTAPPV ... Download FASTA
Job Type	normal
Job Expiry

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:40.590 Y:35.740 Z:52.249

Model (left) based on template c5xfsA_

Top template information

PDB header:protein transport
Chain: A: PDB Molecule:pe family protein pe8;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis

Confidence and coverage

Confidence:

99.9%

Coverage:

78 residues ( 8% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

898 residues ( 97%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

Warning: 76% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in JSmol

For other options to view your downloaded structure offline see the FAQ

Sequence analysis

Download FASTA version

Secondary structure and disorder prediction [Show]

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M S F V V T A P P V L A S A A S D L G G I A S M I S E A N A M A A V R T T A L A P A A A D E V S A A I A A L F S S Y A R

Secondary structure

SS confidence

Disorder ? ? ?
? ?
? ? ? ? ? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence D Y Q T L S V Q V T A F H V Q F A Q T L T N A G Q L Y A V V D V G N G V L L K T E Q Q V L G V I N A P T Q T L V G R P L

Secondary structure

SS confidence

Disorder
? ? ? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence I G D G T H G A P G T G Q N G G A G G I L W G N G G N G G S G A P G Q P G G R G G D A G L F G H G G H G G V G G P G I A

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence G A A G T A G L P G G N G A N G G S G G I G G A G G A G G N G G L L F G N G G A G G Q G G S G G L G G S G G T G G A G M

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence A A G P A G G T G G I G G I G G I G G A G G V G G H G S A L F G H G G I N G D G G T G G M G G Q G G A G G N G W A A E G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence I T V G I G E Q G G Q G G D G G A G G A G G I G G S A G G I G G S Q G A G G H G G D G G Q G G A G G S G G V G G G G A G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence A G G D G G A G G I G G T G G N G S I G G A A G N G G N G G R G G A G G M A T A G S D G G N G G G G G N G G V G V G S A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence G G A G G T G G D G G A A G A G G A P G H G Y F Q Q P A P Q G L P I G T G G T G G E G G A G G A G G D G G Q G D I G F D

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence G G R G G D G G P G G G G G A G G D G S G T F N A Q A N N G G D G G A G G V G G A G G T G G T G G V G A D G G R G G D S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence G R G G D G G N A G H G G A A Q F S G R G A Y G G E G G S G G A G G N A G G A G T G G T A G S G G A G G F G G N G A D G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence G N G G N G G N G G F G G I N G T F G T N G A G G T G G L G T L L G G H N G N I G L N G A T G G I G S T T L T N A T V P

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence L Q L V N T T E P V V F I S L N G G Q M V P V L L D T G S T G L V M D S Q F L T Q N F G P V I G T G T A G Y A G G L T Y

Secondary structure

SS confidence

Disorder
?
? ?
?
? ? ? ? ? ? ?
? ? ?
?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence N Y N T Y S T T V D F G N G L L T L P T S V N V V T S S S P G T L G N F L S R S G A V G V L G I G P N N G F P G T S S I

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence V T A M P G L L N N G V L I D E S A G I L Q F G P N T L T G G I T I S G A P I S T V A V Q I D N G P L Q Q A P V M F D S

Secondary structure

SS confidence

Disorder ? ?
? ? ?
?
?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence G G I N G T I P S A L A S L P S G G F V P A G T T I S V Y T S D G Q T L L Y S Y T T T A T N T P F V T S G G V M N T G H

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ?
? ?
?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . .

Sequence V P F A Q Q P I Y V S Y S P T A I G T T T F N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 76%)

Alpha helix ( 6%)

Beta strand ( 7%)

Domain analysis [Show]

Rank Aligned region

PDB 5xfs chain A

3D model

Region: 7 - 84
Aligned: 78
Modelled: 78
Confidence: 99.9%
Identity: 46%
PDB header:protein transport
Chain: A: PDB Molecule:pe family protein pe8;
PDBTitle: crystal structure of pe8-ppe15 in complex with espg5 from m.2 tuberculosis

Phyre2

PDB 2g38 chain A

3D model

Region: 8 - 84
Aligned: 77
Modelled: 77
Confidence: 99.9%
Identity: 32%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:pe family protein;
PDBTitle: a pe/ppe protein complex from mycobacterium tuberculosis

Phyre2

PDB 2g38 chain A domain 1

3D model

Region: 8 - 84
Aligned: 77
Modelled: 77
Confidence: 99.9%
Identity: 32%
Fold: Ferritin-like
Superfamily: PE/PPE dimer-like
Family: PE

Phyre2

PDB 1ygv chain A

Region: 98 - 776
Aligned: 674
Modelled: 679
Confidence: 99.8%
Identity: 25%
PDB header:structural protein/contractile protein
Chain: A: PDB Molecule:collagen i alpha 1;
PDBTitle: the structure of collagen type i. single type i collagen2 molecule: rigid refinment

Phyre2

PDB 1y0f chain B

3D model

Region: 123 - 717
Aligned: 591
Modelled: 594
Confidence: 99.7%
Identity: 25%
PDB header:structural protein/contractile protein
Chain: B: PDB Molecule:collagen i alpha 2;
PDBTitle: the structure of collagen type i. single type i collagen2 molecule

Phyre2

PDB 3hqv chain B

3D model

Region: 98 - 614
Aligned: 515
Modelled: 517
Confidence: 99.5%
Identity: 26%
PDB header:structural protein, contractile protein
Chain: B: PDB Molecule:collagen alpha-2(i) chain;
PDBTitle: low resolution, molecular envelope structure of type i2 collagen in situ determined by fiber diffraction. single3 type i collagen molecule, rigid body refinement

Phyre2

PDB 2pne chain A

3D model

Region: 122 - 201
Aligned: 80
Modelled: 80
Confidence: 98.1%
Identity: 34%
PDB header:antifreeze protein
Chain: A: PDB Molecule:6.5 kda glycine-rich antifreeze protein;
PDBTitle: crystal structure of the snow flea antifreeze protein

Phyre2

PDB 3boi chain B

3D model

Region: 122 - 201
Aligned: 80
Modelled: 80
Confidence: 98.1%
Identity: 34%
PDB header:antifreeze protein
Chain: B: PDB Molecule:6.5 kda glycine-rich antifreeze protein;
PDBTitle: snow flea antifreeze protein racemate

Phyre2

PDB 3boi chain A

3D model

Region: 122 - 201
Aligned: 80
Modelled: 80
Confidence: 98.1%
Identity: 34%
PDB header:antifreeze protein
Chain: A: PDB Molecule:6.5 kda glycine-rich antifreeze protein;
PDBTitle: snow flea antifreeze protein racemate

Phyre2

PDB 3bog chain B

3D model

Region: 122 - 201
Aligned: 79
Modelled: 80
Confidence: 98.1%
Identity: 33%
PDB header:antifreeze protein
Chain: B: PDB Molecule:6.5 kda glycine-rich antifreeze protein;
PDBTitle: snow flea antifreeze protein quasi-racemate

Phyre2

PDB 3bog chain A

3D model

Region: 122 - 201
Aligned: 79
Modelled: 80
Confidence: 98.1%
Identity: 33%
PDB header:antifreeze protein
Chain: A: PDB Molecule:6.5 kda glycine-rich antifreeze protein;
PDBTitle: snow flea antifreeze protein quasi-racemate

Phyre2

PDB 4ehc chain A

3D model

Region: 671 - 920
Aligned: 250
Modelled: 250
Confidence: 97.8%
Identity: 97%
PDB header:hydrolase
Chain: A: PDB Molecule:pe-pgrs family protein;
PDBTitle: crystal structure of the c-terminal domain of rv0977 of mycobacterium2 tuberculosis

Phyre2

PDB 1k7q chain A

3D model

Region: 170 - 549
Aligned: 380
Modelled: 380
Confidence: 97.3%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:secreted protease c;
PDBTitle: prtc from erwinia chrysanthemi: e189a mutant

Phyre2

PDB 1nay chain C

Region: 124 - 171
Aligned: 48
Modelled: 48
Confidence: 96.3%
Identity: 29%
PDB header:structural protein
Chain: C: PDB Molecule:collagen-like peptide;
PDBTitle: gpp-foldon:x-ray structure

Phyre2

PDB 5ctd chain B

3D model

Region: 124 - 162
Aligned: 39
Modelled: 39
Confidence: 96.3%
Identity: 38%
PDB header:structural protein
Chain: B: PDB Molecule:collagen alpha-2(i) chain,collagen alpha-2(ix) chain;
PDBTitle: crystal structure of the type ix collagen nc2 hetero-trimerization2 domain with a guest fragment a2a1a1 of type i collagen

Phyre2

PDB 2ml3 chain A

3D model

Region: 171 - 349
Aligned: 177
Modelled: 179
Confidence: 96.1%
Identity: 20%
PDB header:isomerase
Chain: A: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 6;
PDBTitle: solution structure of alge6r3 subunit from the azotobacter vinelandii2 mannuronan c5-epimerase

Phyre2

PDB 5ctd chain A

3D model

Region: 124 - 162
Aligned: 39
Modelled: 39
Confidence: 96.0%
Identity: 38%
PDB header:structural protein
Chain: A: PDB Molecule:collagen alpha-1(i) chain,collagen alpha-1(ix) chain;
PDBTitle: crystal structure of the type ix collagen nc2 hetero-trimerization2 domain with a guest fragment a2a1a1 of type i collagen

Phyre2

PDB 5cti chain C

3D model

Region: 124 - 162
Aligned: 39
Modelled: 39
Confidence: 95.9%
Identity: 36%
PDB header:structural protein
Chain: C: PDB Molecule:collagen alpha-1(i) chain,collagen alpha-3(ix) chain;
PDBTitle: crystal structure of the type ix collagen nc2 hetero-trimerization2 domain with a guest fragment a2a1a1 of type i collagen (native form)

Phyre2

PDB 2zj6 chain A

3D model

Region: 163 - 222
Aligned: 60
Modelled: 60
Confidence: 95.5%
Identity: 28%
PDB header:hydrolase
Chain: A: PDB Molecule:lipase;
PDBTitle: crystal structure of d337a mutant of pseudomonas sp. mis38 lipase

Phyre2

PDB 1kap chain P domain 1

Region: 154 - 215
Aligned: 62
Modelled: 62
Confidence: 94.6%
Identity: 31%
Fold: Single-stranded right-handed beta-helix
Superfamily: beta-Roll
Family: Serralysin-like metalloprotease, C-terminal domain

Phyre2

1
c5xfsA_

2
c2g38A_

3
d2g38a1

4
c1ygvA_

5
c1y0fB_

6
c3hqvB_

7
c2pneA_

8
c3boiB_

9
c3boiA_

10
c3bogB_

11
c3bogA_

12
c4ehcA_

13
c1k7qA_

14
c1nayC_

15
c5ctdB_

16
c2ml3A_

17
c5ctdA_

18
c5ctiC_

19
c2zj6A_

20
d1kapp1

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