Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD0985c_(mscL)_1101029_1101484
DateWed Jul 31 22:05:05 BST 2019
Unique Job IDe9dcfa598f16004e
SequenceMLKGFKEFLA ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:61.529 Y:71.845 Z:47.085
Model (left) based on template c2oarA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: mechanosensitive channel of large conductance (mscl)
Confidence and coverage
Confidence:100.0% Coverage: 83%
125 residues ( 83% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2oarA_
100.0 100
PDB header:membrane protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: mechanosensitive channel of large conductance (mscl)
2d2oara1
100.0 100
Fold:Gated mechanosensitive channel
Superfamily:Gated mechanosensitive channel
Family:Gated mechanosensitive channel
3c4y7jE_
100.0 34
PDB header:membrane protein,transport protein
Chain: E: PDB Molecule:large conductance mechanosensitive channel protein,
PDBTitle: structure of an archaeal mechanosensitive channel in expanded state
4c3hzqA_
100.0 40
PDB header:membrane protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of a tetrameric mscl in an expanded intermediate state
5c4lkuA_
97.4 42
PDB header:transport protein
Chain: A: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of the c-terminal domain of the e. coli mechanosensitive2 channel of large conductance
6c4lkuB_
97.4 42
PDB header:transport protein
Chain: B: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of the c-terminal domain of the e. coli mechanosensitive2 channel of large conductance
7c4lkuD_
97.2 50
PDB header:transport protein
Chain: D: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of the c-terminal domain of the e. coli mechanosensitive2 channel of large conductance
8c4lkuC_
97.1 52
PDB header:transport protein
Chain: C: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of the c-terminal domain of the e. coli mechanosensitive2 channel of large conductance
9c4lkuE_
96.8 55
PDB header:transport protein
Chain: E: PDB Molecule:large-conductance mechanosensitive channel;
PDBTitle: structure of the c-terminal domain of the e. coli mechanosensitive2 channel of large conductance
10c6fkib_
82.5 16
PDB header:membrane protein
Chain: B: PDB Molecule:atp synthase subunit beta, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
11c6fkip_
80.8 16
PDB header:membrane protein
Chain: P: PDB Molecule:atp synthase subunit c, chloroplastic;
PDBTitle: chloroplast f1fo conformation 3
12c5t4oJ_
78.3 25
PDB header:hydrolase
Chain: J: PDB Molecule:atp synthase subunit b;
PDBTitle: autoinhibited e. coli atp synthase state 1
13c4rp9A_
78.0 13
PDB header:membrane protein
Chain: A: PDB Molecule:ascorbate-specific permease iic component ulaa;
PDBTitle: bacterial vitamin c transporter ulaa/sgat in c2 form
14c2rddB_
72.9 16
PDB header:membrane protein/transport protein
Chain: B: PDB Molecule:upf0092 membrane protein yajc;
PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix.
15c3qnqD_
70.1 17
PDB header:membrane protein, transport protein
Chain: D: PDB Molecule:pts system, cellobiose-specific iic component;
PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system
16c4uotE_
49.6 50
PDB header:de novo protein
Chain: E: PDB Molecule:designed helical bundle 5h2l;
PDBTitle: thermodynamic hyperstability in parametrically designed2 helical bundles
17c4uotC_
49.6 50
PDB header:de novo protein
Chain: C: PDB Molecule:designed helical bundle 5h2l;
PDBTitle: thermodynamic hyperstability in parametrically designed2 helical bundles
18c4uotA_
49.6 50
PDB header:de novo protein
Chain: A: PDB Molecule:designed helical bundle 5h2l;
PDBTitle: thermodynamic hyperstability in parametrically designed2 helical bundles
19c4uotD_
49.6 50
PDB header:de novo protein
Chain: D: PDB Molecule:designed helical bundle 5h2l;
PDBTitle: thermodynamic hyperstability in parametrically designed2 helical bundles
20c4uotB_
49.6 50
PDB header:de novo protein
Chain: B: PDB Molecule:designed helical bundle 5h2l;
PDBTitle: thermodynamic hyperstability in parametrically designed2 helical bundles
21c3t98C_
not modelled 46.7 38
PDB header:protein transport
Chain: C: PDB Molecule:nuclear pore complex protein nup54;
PDBTitle: molecular architecture of the transport channel of the nuclear pore2 complex: nup54/nup58
22c5v2sA_
not modelled 32.4 25
PDB header:viral protein
Chain: A: PDB Molecule:envelope glycoprotein b;
PDBTitle: crystal structure of glycoprotein b from herpes simplex virus type i
23d1q1va_
not modelled 31.1 29
Fold:Another 3-helical bundle
Superfamily:DEK C-terminal domain
Family:DEK C-terminal domain
24c3t98A_
not modelled 30.6 38
PDB header:protein transport
Chain: A: PDB Molecule:nuclear pore complex protein nup54;
PDBTitle: molecular architecture of the transport channel of the nuclear pore2 complex: nup54/nup58
25c1vdfB_
not modelled 27.5 38
PDB header:extracellular matrix protein
Chain: B: PDB Molecule:cartilage oligomeric matrix protein;
PDBTitle: assembly domain of cartilage oligomeric matrix protein
26c4kjsB_
not modelled 27.4 11
PDB header:transport protein
Chain: B: PDB Molecule:cation exchanger yfke;
PDBTitle: structure of native yfke
27c2l35B_
not modelled 26.0 40
PDB header:protein binding
Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer
28c2lseA_
not modelled 25.6 37
PDB header:de novo protein
Chain: A: PDB Molecule:four helix bundle protein;
PDBTitle: solution nmr structure of de novo designed four helix bundle protein,2 northeast structural genomics consortium (nesg) target or188
29c4wolA_
not modelled 24.9 40
PDB header:signaling protein
Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipidic cubic2 phase
30c2l34A_
not modelled 24.9 40
PDB header:protein binding
Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: structure of the dap12 transmembrane homodimer
31c2l34B_
not modelled 24.9 40
PDB header:protein binding
Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: structure of the dap12 transmembrane homodimer
32c4wo1D_
not modelled 24.3 40
PDB header:signaling protein
Chain: D: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipid cubic2 phase
33c4wo1A_
not modelled 24.3 40
PDB header:signaling protein
Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipid cubic2 phase
34c4wo1B_
not modelled 24.3 40
PDB header:signaling protein
Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipid cubic2 phase
35c4wo1C_
not modelled 24.3 40
PDB header:signaling protein
Chain: C: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipid cubic2 phase
36c4wolB_
not modelled 23.6 40
PDB header:signaling protein
Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipidic cubic2 phase
37c4wolC_
not modelled 23.6 40
PDB header:signaling protein
Chain: C: PDB Molecule:tyro protein tyrosine kinase-binding protein;
PDBTitle: crystal structure of the dap12 transmembrane domain in lipidic cubic2 phase
38c6g6hA_
not modelled 22.7 44
PDB header:de novo protein
Chain: A: PDB Molecule:5h2l_2.1-i9l;
PDBTitle: crystal structure of an antiparallel five-helix coiled coil 5h2l_2.1-2 i9l
39c6g6hB_
not modelled 22.7 44
PDB header:de novo protein
Chain: B: PDB Molecule:5h2l_2.1-i9l;
PDBTitle: crystal structure of an antiparallel five-helix coiled coil 5h2l_2.1-2 i9l
40c6g6hC_
not modelled 22.7 44
PDB header:de novo protein
Chain: C: PDB Molecule:5h2l_2.1-i9l;
PDBTitle: crystal structure of an antiparallel five-helix coiled coil 5h2l_2.1-2 i9l
41c6g6hE_
not modelled 22.7 44
PDB header:de novo protein
Chain: E: PDB Molecule:5h2l_2.1-i9l;
PDBTitle: crystal structure of an antiparallel five-helix coiled coil 5h2l_2.1-2 i9l
42c6g6hD_
not modelled 22.7 44
PDB header:de novo protein
Chain: D: PDB Molecule:5h2l_2.1-i9l;
PDBTitle: crystal structure of an antiparallel five-helix coiled coil 5h2l_2.1-2 i9l
43d2ctda1
not modelled 19.6 24
Fold:beta-beta-alpha zinc fingers
Superfamily:beta-beta-alpha zinc fingers
Family:Classic zinc finger, C2H2
44c5xugB_
not modelled 17.6 45
PDB header:hydrolase
Chain: B: PDB Molecule:endo-1,4-beta-mannanase;
PDBTitle: complex structure(rmman134a-m5).
45c4k1cB_
not modelled 15.2 29
PDB header:membrane protein/metal transport
Chain: B: PDB Molecule:vacuolar calcium ion transporter;
PDBTitle: vcx1 calcium/proton exchanger
46c4jd9B_
not modelled 14.7 27
PDB header:protein binding
Chain: B: PDB Molecule:14.5 kda salivary protein;
PDBTitle: contact pathway inhibitor from a sand fly
47d2b3wa1
not modelled 14.6 43
Fold:YbiA-like
Superfamily:YbiA-like
Family:YbiA-like
48c4z3pA_
not modelled 13.8 26
PDB header:transport protein
Chain: A: PDB Molecule:putative drug/sodium antiporter;
PDBTitle: mate transporter clbm in complex with rb+
49d1sh0a_
not modelled 12.9 18
Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:RNA-dependent RNA-polymerase
50c5zovA_
not modelled 12.3 11
PDB header:transport protein
Chain: A: PDB Molecule:pts ascorbate-specific subunit iibc;
PDBTitle: inward-facing conformation of l-ascorbate transporter ulaa
51c5lnk2_
not modelled 12.3 29
PDB header:oxidoreductase
Chain: 2: PDB Molecule:mitochondrial complex i, 24 kda subunit;
PDBTitle: entire ovine respiratory complex i
52c4zrkH_
not modelled 11.8 63
PDB header:signaling protein/transferase
Chain: H: PDB Molecule:serine/threonine-protein kinase lats1;
PDBTitle: merlin-ferm and lats1 complex
53c4zrkE_
not modelled 11.8 63
PDB header:signaling protein/transferase
Chain: E: PDB Molecule:serine/threonine-protein kinase lats1;
PDBTitle: merlin-ferm and lats1 complex
54c4zrkF_
not modelled 11.8 63
PDB header:signaling protein/transferase
Chain: F: PDB Molecule:serine/threonine-protein kinase lats1;
PDBTitle: merlin-ferm and lats1 complex
55c4zrkG_
not modelled 11.8 63
PDB header:signaling protein/transferase
Chain: G: PDB Molecule:serine/threonine-protein kinase lats1;
PDBTitle: merlin-ferm and lats1 complex
56c2l35A_
not modelled 11.1 40
PDB header:protein binding
Chain: A: PDB Molecule:dap12-nkg2c_tm;
PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer
57c2uutA_
not modelled 11.1 29
PDB header:hydrolase
Chain: A: PDB Molecule:rna-directed rna polymerase;
PDBTitle: the 2.4 angstrom resolution structure of the d346g mutant of the2 sapporo virus rdrp polymerase
58c2b43D_
not modelled 10.3 18
PDB header:viral protein
Chain: D: PDB Molecule:non-structural polyprotein;
PDBTitle: crystal structure of the norwalk virus rna dependent rna polymerase2 from strain hu/nlv/dresden174/1997/ge
59c2yubA_
not modelled 10.0 20
PDB header:transferase
Chain: A: PDB Molecule:lim domain kinase 2;
PDBTitle: solution structure of the pdz domain from mouse lim domain2 kinase
60c1c94B_
not modelled 9.7 45
PDB header:gene regulation
Chain: B: PDB Molecule:retro-gcn4 leucine zipper;
PDBTitle: reversing the sequence of the gcn4 leucine zipper does not affect its2 fold.
61c6a6iG_
not modelled 9.7 19
PDB header:hydrolase
Chain: G: PDB Molecule:excision repair cross-complementing rodent repair
PDBTitle: crystal structure of the winged-helix domain of cockayne syndrome2 group b protein in complex with ubiquitin
62c4g9iA_
not modelled 9.6 18
PDB header:transferase
Chain: A: PDB Molecule:hydrogenase maturation protein hypf;
PDBTitle: crystal structure of t.kodakarensis hypf
63c3vthB_
not modelled 9.4 24
PDB header:transferase
Chain: B: PDB Molecule:hydrogenase maturation factor;
PDBTitle: crystal structure of full-length hypf in the phosphate- and2 nucleotide-bound form
64c2jpnA_
not modelled 8.5 67
PDB header:hydrolase
Chain: A: PDB Molecule:atp-dependent dna helicase uvsw;
PDBTitle: solution structure of t4 bacteriophage helicase uvsw.1
65d1khva_
not modelled 8.4 18
Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:RNA-dependent RNA-polymerase
66d1lm8v_
not modelled 8.4 19
Fold:Prealbumin-like
Superfamily:VHL
Family:VHL
67c3m91B_
not modelled 8.0 46
PDB header:hydrolase regulator
Chain: B: PDB Molecule:prokaryotic ubiquitin-like protein pup;
PDBTitle: crystal structure of the prokaryotic ubiquitin-like protein (pup)2 complexed with the amino terminal coiled coil of the mycobacterium3 tuberculosis proteasomal atpase mpa
68c3m91D_
not modelled 8.0 46
PDB header:hydrolase regulator
Chain: D: PDB Molecule:prokaryotic ubiquitin-like protein pup;
PDBTitle: crystal structure of the prokaryotic ubiquitin-like protein (pup)2 complexed with the amino terminal coiled coil of the mycobacterium3 tuberculosis proteasomal atpase mpa
69c3vthA_
not modelled 7.8 19
PDB header:transferase
Chain: A: PDB Molecule:hydrogenase maturation factor;
PDBTitle: crystal structure of full-length hypf in the phosphate- and2 nucleotide-bound form
70c2n28A_
not modelled 7.7 21
PDB header:viral protein
Chain: A: PDB Molecule:protein vpu;
PDBTitle: solid-state nmr structure of vpu
71c5jtsA_
not modelled 7.0 55
PDB header:hydrolase
Chain: A: PDB Molecule:beta-1,4-mannanase;
PDBTitle: structure of a beta-1,4-mannanase, ssgh134.
72c5yxwA_
not modelled 7.0 25
PDB header:viral protein
Chain: A: PDB Molecule:glycoprotein f2;
PDBTitle: crystal structure of the prefusion form of measles virus fusion2 protein
73c4rfsS_
not modelled 6.9 14
PDB header:hydrolase, transport protein
Chain: S: PDB Molecule:substrate binding pritein s;
PDBTitle: structure of a pantothenate energy coupling factor transporter
74c5sy1A_
not modelled 6.8 36
PDB header:membrane protein/calcium binding protein
Chain: A: PDB Molecule:stra6;
PDBTitle: structure of the stra6 receptor for retinol uptake in complex with2 calmodulin
75c6fddC_
not modelled 6.7 33
PDB header:structural protein
Chain: C: PDB Molecule:whirlin;
PDBTitle: crystal structure of the hhd2 domain of whirlin
76c4f0qA_
not modelled 6.7 14
PDB header:hydrolase
Chain: A: PDB Molecule:restriction endonuclease;
PDBTitle: mspji restriction endonuclease - p21 form
77c2hdeA_
not modelled 6.6 15
PDB header:transcription
Chain: A: PDB Molecule:histone deacetylase complex subunit sap18;
PDBTitle: solution structure of human sap18
78c3m9dR_
not modelled 6.5 29
PDB header:chaperone
Chain: R: PDB Molecule:prokaryotic ubiquitin-like protein pup;
PDBTitle: crystal structure of the prokaryotic ubiquintin-like protein pup2 complexed with the hexameric proteasomal atpase mpa which includes3 the amino terminal coiled coil domain and the inter domain
79c2j5dA_
not modelled 6.5 25
PDB header:membrane protein
Chain: A: PDB Molecule:bcl2/adenovirus e1b 19 kda protein-interacting protein 3;
PDBTitle: nmr structure of bnip3 transmembrane domain in lipid bicelles
80c4g29A_
not modelled 6.3 12
PDB header:protein binding
Chain: A: PDB Molecule:secreted effector protein ssei;
PDBTitle: structure of the catalytic domain of the salmonella virulence factor2 ssei
81c4bl0B_
not modelled 6.2 33
PDB header:cell cycle
Chain: B: PDB Molecule:checkpoint serine/threonine-protein kinase bub1;
PDBTitle: crystal structure of yeast bub3-bub1 bound to phospho-spc105
82c4f0qC_
not modelled 6.2 12
PDB header:hydrolase
Chain: C: PDB Molecule:restriction endonuclease;
PDBTitle: mspji restriction endonuclease - p21 form
83c5o9zH_
not modelled 6.0 26
PDB header:splicing
Chain: H: PDB Molecule:u4/u6 small nuclear ribonucleoprotein prp31;
PDBTitle: cryo-em structure of a pre-catalytic human spliceosome primed for2 activation (b complex)
84c3nahC_
not modelled 5.9 24
PDB header:transferase
Chain: C: PDB Molecule:rna dependent rna polymerase;
PDBTitle: crystal structures and functional analysis of murine norovirus rna-2 dependent rna polymerase
85d1xr6a_
not modelled 5.8 24
Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:RNA-dependent RNA-polymerase
86c2ka1A_
not modelled 5.8 25
PDB header:membrane protein
Chain: A: PDB Molecule:bcl2/adenovirus e1b 19 kda protein-interacting
PDBTitle: solution nmr structure of bnip3 transmembrane peptide dimer2 in detergent micelles
87c2ka2B_
not modelled 5.8 25
PDB header:membrane protein
Chain: B: PDB Molecule:bcl2/adenovirus e1b 19 kda protein-interacting
PDBTitle: solution nmr structure of bnip3 transmembrane peptide dimer2 in detergent micelles with his173-ser172 intermonomer3 hydrogen bond restraints
88c2ka1B_
not modelled 5.8 25
PDB header:membrane protein
Chain: B: PDB Molecule:bcl2/adenovirus e1b 19 kda protein-interacting
PDBTitle: solution nmr structure of bnip3 transmembrane peptide dimer2 in detergent micelles
89c2ka2A_
not modelled 5.8 25
PDB header:membrane protein
Chain: A: PDB Molecule:bcl2/adenovirus e1b 19 kda protein-interacting
PDBTitle: solution nmr structure of bnip3 transmembrane peptide dimer2 in detergent micelles with his173-ser172 intermonomer3 hydrogen bond restraints
90d1g8eb_
not modelled 5.8 44
Fold:Flagellar transcriptional activator FlhD
Superfamily:Flagellar transcriptional activator FlhD
Family:Flagellar transcriptional activator FlhD
91c6c90B_
not modelled 5.7 44
PDB header:hydrolase/rna binding protein
Chain: B: PDB Molecule:zinc finger cchc domain-containing protein 8;
PDBTitle: human mtr4 helicase in complex with zcchc8-ctd
92c3iv0A_
not modelled 5.7 13
PDB header:sugar binding protein
Chain: A: PDB Molecule:susd homolog;
PDBTitle: crystal structure of susd homolog (np_809186.1) from bacteroides2 thetaiotaomicron vpi-5482 at 1.35 a resolution
93c2lnaA_
not modelled 5.7 31
PDB header:hydrolase
Chain: A: PDB Molecule:afg3-like protein 2;
PDBTitle: solution nmr structure of the mitochondrial inner membrane domain2 (residues 164-251), ftsh_ext, from the paraplegin-like protein afg3l23 from homo sapiens, northeast structural genomics consortium target4 hr6741a
94c5edlA_
not modelled 5.7 12
PDB header:transport protein
Chain: A: PDB Molecule:putative hmp/thiamine permease protein ykoe;
PDBTitle: crystal structure of an s-component of ecf transporter
95c2m0oA_
not modelled 5.6 44
PDB header:peptide binding protein
Chain: A: PDB Molecule:phd finger protein 1;
PDBTitle: the solution structure of human phf1 in complex with h3k36me3
96d1nara_
not modelled 5.6 12
Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Type II chitinase
97d1u09a_
not modelled 5.5 18
Fold:DNA/RNA polymerases
Superfamily:DNA/RNA polymerases
Family:RNA-dependent RNA-polymerase
98d1xpja_
not modelled 5.5 33
Fold:HAD-like
Superfamily:HAD-like
Family:Hypothetical protein VC0232
99c3si5X_
not modelled 5.4 38
PDB header:cell cycle
Chain: X: PDB Molecule:protein casc5;
PDBTitle: kinetochore-bubr1 kinase complex

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below