1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	K	S	A	S	N	Q	L	R	V	T	V	R	T	E	T	G	K	G	A	S	R	R	A	R	R	A	G	K	I	P	A	V	L	Y	G	H	G	A	E	P	Q	H	L	E	L	P	G	H	D	Y	A	A	V	L	R	H	S	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	N	A	V	L	T	L	D	I	A	G	K	E	Q	L	A	L	T	K	A	L	H	I	H	P	I	R	R	T	I	Q	H	A	D	L	L	V	V	R	R	G	E	K	V	V	V	E	V	S	V	V	V	E	G	Q	A	G	P	D	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	V	T	Q	E	T	N	S	I	E	I	E	A	E	A	L	S	I	P	E	Q	L	T	V	S	I	E	G	A	E	P	G	T	Q	L	T	A	G	Q	I	A	L	P	A	G	V	S	L	I	S	D	P	D	L	L	V	V	N	V	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
Sequence		K	A	P	T	A	E	E	L	E	G	E	V	A	G	A	E	E	A	E	E	A	A	V	E	A	G	E	A	E	A	A	G	E	S	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 21%) Alpha helix ( 10%) Beta strand ( 46%)

Rank Aligned region

PDB 5o60 chain W Region: 6 - 193 Aligned: 188 Modelled: 188 Confidence: 100.0% Identity: 76% PDB header:ribosome Chain: W: PDB Molecule:50s ribosomal protein l25; PDBTitle: structure of the 50s large ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 1feu chain A Region: 7 - 190 Aligned: 179 Modelled: 184 Confidence: 100.0% Identity: 26% Fold: Ribosomal protein L25-like Superfamily: Ribosomal protein L25-like Family: Ribosomal protein L25-like Phyre2 PDB 1njp chain T Region: 8 - 215 Aligned: 201 Modelled: 207 Confidence: 100.0% Identity: 30% PDB header:ribosome Chain: T: PDB Molecule:general stress protein ctc; PDBTitle: the crystal structure of the 50s large ribosomal subunit2 from deinococcus radiodurans complexed with a trna3 acceptor stem mimic (asm) Phyre2 PDB 2zjr chain S domain 1 Region: 8 - 183 Aligned: 169 Modelled: 169 Confidence: 100.0% Identity: 30% Fold: Ribosomal protein L25-like Superfamily: Ribosomal protein L25-like Family: Ribosomal protein L25-like Phyre2 PDB 2b9n chain Z Region: 8 - 183 Aligned: 169 Modelled: 169 Confidence: 100.0% Identity: 30% PDB header:ribosome Chain: Z: PDB Molecule:50s ribosomal protein ctc; PDBTitle: 50s ribosomal subunit from a crystal structure of release factor rf2,2 trnas and mrna bound to the ribosome. this file contains the 50s3 subunit from a crystal structure of release factor rf1, trnas and4 mrna bound to the ribosome and is described in remark 400. Phyre2 PDB 4wfb chain S Region: 8 - 170 Aligned: 153 Modelled: 163 Confidence: 100.0% Identity: 25% PDB header:ribosome Chain: S: PDB Molecule:50s ribosomal protein l25; PDBTitle: the crystal structure of the large ribosomal subunit of staphylococcus2 aureus in complex with bc-3205 Phyre2 PDB 5izn chain H Region: 7 - 98 Aligned: 92 Modelled: 91 Confidence: 100.0% Identity: 34% PDB header:ribosomal protein Chain: H: PDB Molecule:50s ribosomal protein l25; PDBTitle: the crystal structure of 50s ribosomal protein l25 from vibrio2 vulnificus cmcp6 Phyre2 PDB 1dfu chain P Region: 8 - 97 Aligned: 90 Modelled: 90 Confidence: 100.0% Identity: 34% Fold: Ribosomal protein L25-like Superfamily: Ribosomal protein L25-like Family: Ribosomal protein L25-like Phyre2 PDB 1bdf chain A domain 2 Region: 154 - 179 Aligned: 25 Modelled: 26 Confidence: 61.2% Identity: 20% Fold: Insert subdomain of RNA polymerase alpha subunit Superfamily: Insert subdomain of RNA polymerase alpha subunit Family: Insert subdomain of RNA polymerase alpha subunit Phyre2 PDB 2kps chain A Region: 141 - 176 Aligned: 36 Modelled: 36 Confidence: 58.1% Identity: 28% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of domain iv from the ybbr family protein of2 desulfitobacterium hafniense Phyre2 PDB 2lyx chain A Region: 65 - 97 Aligned: 33 Modelled: 33 Confidence: 45.6% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein yqzg; PDBTitle: nmr structure of the protein np_390345.1 from bacilus subtilis Phyre2 PDB 1zak chain A domain 2 Region: 84 - 95 Aligned: 12 Modelled: 12 Confidence: 43.3% Identity: 25% Fold: Rubredoxin-like Superfamily: Microbial and mitochondrial ADK, insert "zinc finger" domain Family: Microbial and mitochondrial ADK, insert "zinc finger" domain Phyre2 PDB 1htw chain A Region: 77 - 103 Aligned: 25 Modelled: 27 Confidence: 37.7% Identity: 28% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: YjeE-like Phyre2 PDB 1ynj chain A domain 2 Region: 154 - 182 Aligned: 28 Modelled: 29 Confidence: 35.6% Identity: 25% Fold: Insert subdomain of RNA polymerase alpha subunit Superfamily: Insert subdomain of RNA polymerase alpha subunit Family: Insert subdomain of RNA polymerase alpha subunit Phyre2 PDB 6fpe chain E Region: 81 - 102 Aligned: 22 Modelled: 22 Confidence: 31.4% Identity: 27% PDB header:rna binding protein Chain: E: PDB Molecule:atpase yjee, predicted to have essential role in cell wall PDBTitle: bacterial protein complex Phyre2 PDB 6j9e chain A Region: 154 - 184 Aligned: 30 Modelled: 31 Confidence: 31.2% Identity: 23% PDB header:transcription Chain: A: PDB Molecule:dna-directed rna polymerase subunit alpha; PDBTitle: cryo-em structure of xanthomonos oryzae transcription elongation2 complex with nusa and the bacteriophage protein p7 Phyre2 PDB 5tw1 chain A Region: 154 - 183 Aligned: 29 Modelled: 30 Confidence: 29.1% Identity: 34% PDB header:transcription activator/transferase/dna Chain: A: PDB Molecule:dna-directed rna polymerase subunit alpha; PDBTitle: crystal structure of a mycobacterium smegmatis transcription2 initiation complex with rbpa Phyre2 PDB 1bdf chain C Region: 154 - 182 Aligned: 28 Modelled: 29 Confidence: 28.6% Identity: 18% PDB header:nucleotidyltransferase Chain: C: PDB Molecule:rna polymerase alpha subunit; PDBTitle: structure of escherichia coli rna polymerase alpha subunit2 n-terminal domain Phyre2 PDB 5hqh chain A Region: 101 - 186 Aligned: 85 Modelled: 86 Confidence: 28.5% Identity: 16% PDB header:unknown function Chain: A: PDB Molecule:lmo2119 protein; PDBTitle: 1.32 angstrom crystal structure of ybbr like domain of lmo2119 protein2 from listeria monocytogenes. Phyre2 PDB 2nvg chain A Region: 141 - 158 Aligned: 18 Modelled: 18 Confidence: 26.0% Identity: 39% PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: soluble domain of rieske iron sulfur protein. Phyre2 1 c5o60W_ 2 d1feua_ 3 c1njpT_ 4 d2zjrs1 5 c2b9nZ_ 6 c4wfbS_ 7 c5iznH_ 8 d1dfup_ 9 d1bdfa2 10 c2kpsA_ 11 c2lyxA_ 12 d1zaka2 13 d1htwa_ 14 d1ynja2 15 c6fpeE_ 16 c6j9eA_ 17 c5tw1A_ 18 c1bdfC_ 19 c5hqhA_ 20 c2nvgA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99