1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	V	T	R	Q	L	G	R	A	P	R	G	V	L	A	I	A	Y	R	C	P	N	G	E	P	G	V	V	K	T	A	P	R	L	P	D	G	T	P	F	P	T	L	Y	Y	L	T	H	P	V	L	T	A	A	A	S	R	L	E	T
Secondary structure
SS confidence
Disorder		?	?			?	?	?																								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	G	L	M	R	E	M	N	R	R	L	G	Q	D	A	E	L	A	A	A	Y	R	R	A	H	E	S	Y	L	S	E	R	D	A	L	E	P	L	G	T	T	V	S	A	G	G	M	P	D	R	V	K	C	L	H	V	L	I	A	H
Secondary structure
SS confidence
Disorder													?																									?	?			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Sequence		S	L	A	K	G	P	G	L	N	P	F	G	D	E	A	L	A	L	L	A	A	E	P	R	T	A	A	T	L	V	A	G	Q	W	R
Secondary structure
SS confidence
Disorder																										?				?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 15%) Alpha helix ( 55%) Beta strand ( 7%)

Rank Aligned region

PDB 2gno chain A domain 1 Region: 45 - 73 Aligned: 29 Modelled: 29 Confidence: 52.8% Identity: 17% Fold: post-AAA+ oligomerization domain-like Superfamily: post-AAA+ oligomerization domain-like Family: DNA polymerase III clamp loader subunits, C-terminal domain Phyre2 PDB 4is4 chain G Region: 17 - 62 Aligned: 41 Modelled: 46 Confidence: 42.0% Identity: 22% PDB header:ligase Chain: G: PDB Molecule:glutamine synthetase; PDBTitle: the glutamine synthetase from the dicotyledonous plant m. truncatula2 is a decamer Phyre2 PDB 5z58 chain W Region: 32 - 46 Aligned: 13 Modelled: 15 Confidence: 37.1% Identity: 31% PDB header:splicing Chain: W: PDB Molecule: PDBTitle: cryo-em structure of a human activated spliceosome (early bact) at 4.92 angstrom. Phyre2 PDB 6g90 chain T Region: 32 - 46 Aligned: 13 Modelled: 15 Confidence: 35.3% Identity: 23% PDB header:splicing Chain: T: PDB Molecule:pre-mrna-splicing factor prp9; PDBTitle: prespliceosome structure provides insight into spliceosome assembly2 and regulation (map a2) Phyre2 PDB 2kz3 chain A Region: 48 - 106 Aligned: 59 Modelled: 59 Confidence: 33.3% Identity: 17% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein rad51l3; PDBTitle: backbone 1h, 13c, and 15n chemical shift assignments for human rad51d2 from 1 to 83 Phyre2 PDB 3tgn chain A Region: 49 - 101 Aligned: 53 Modelled: 53 Confidence: 25.8% Identity: 17% PDB header:transcription Chain: A: PDB Molecule:adc operon repressor adcr; PDBTitle: crystal structure of the zinc-dependent marr family transcriptional2 regulator adcr in the zn(ii)-bound state Phyre2 PDB 1bih chain A domain 2 Region: 14 - 46 Aligned: 31 Modelled: 33 Confidence: 20.4% Identity: 19% Fold: Immunoglobulin-like beta-sandwich Superfamily: Immunoglobulin Family: I set domains Phyre2 PDB 2ouw chain A domain 1 Region: 47 - 135 Aligned: 89 Modelled: 89 Confidence: 18.2% Identity: 20% Fold: AhpD-like Superfamily: AhpD-like Family: TTHA0727-like Phyre2 PDB 2e5e chain A Region: 23 - 46 Aligned: 22 Modelled: 24 Confidence: 17.3% Identity: 32% PDB header:signaling protein Chain: A: PDB Molecule:advanced glycosylation end product-specific PDBTitle: solution structure of variable-type domain of human2 receptor for advanced glycation endproducts Phyre2 PDB 2r85 chain B Region: 11 - 45 Aligned: 35 Modelled: 35 Confidence: 15.5% Identity: 26% PDB header:unknown function Chain: B: PDB Molecule:purp protein pf1517; PDBTitle: crystal structure of purp from pyrococcus furiosus complexed with amp Phyre2 PDB 1vw4 chain L Region: 21 - 62 Aligned: 38 Modelled: 42 Confidence: 15.0% Identity: 26% PDB header:ribosome Chain: L: PDB Molecule:54s ribosomal protein l8, mitochondrial; PDBTitle: structure of the yeast mitochondrial large ribosomal subunit Phyre2 PDB 5hsm chain A Region: 49 - 101 Aligned: 53 Modelled: 53 Confidence: 14.1% Identity: 15% PDB header:transcription Chain: A: PDB Molecule:uncharacterized hth-type transcriptional regulator rv2887; PDBTitle: crystal structure of mycobacterium tuberculosis marr family protein2 rv2887 Phyre2 PDB 5b42 chain A Region: 20 - 29 Aligned: 10 Modelled: 10 Confidence: 13.7% Identity: 50% PDB header:dna binding protein Chain: A: PDB Molecule:dna mismatch repair protein mutl; PDBTitle: crystal structure of the c-terminal endonuclease domain of aquifex2 aeolicus mutl. Phyre2 PDB 4fx0 chain A Region: 49 - 101 Aligned: 48 Modelled: 53 Confidence: 13.3% Identity: 23% PDB header:transcription regulator Chain: A: PDB Molecule:probable transcriptional repressor protein; PDBTitle: crystal structure of m. tuberculosis transcriptional regulator mosr Phyre2 PDB 5yhx chain H Region: 46 - 103 Aligned: 58 Modelled: 58 Confidence: 12.6% Identity: 10% PDB header:metal binding protein Chain: H: PDB Molecule:zinc transport transcriptional regulator; PDBTitle: structure of lactococcus lactis zitr, wild type Phyre2 PDB 5ioo chain A Region: 19 - 72 Aligned: 44 Modelled: 54 Confidence: 12.3% Identity: 32% PDB header:unknown function Chain: A: PDB Molecule:avpa; PDBTitle: accommodation of massive sequence variation in nanoarchaeota by the c-2 type lectin fold Phyre2 PDB 2wx4 chain C Region: 58 - 84 Aligned: 27 Modelled: 27 Confidence: 11.9% Identity: 22% PDB header:structural protein Chain: C: PDB Molecule:decapping protein 1; PDBTitle: asymmetric trimer of the drosophila melanogaster dcp1 c-2 terminal domain Phyre2 PDB 2npl chain X Region: 23 - 46 Aligned: 22 Modelled: 24 Confidence: 11.6% Identity: 14% PDB header:cell adhesion Chain: X: PDB Molecule:coxsackievirus and adenovirus receptor; PDBTitle: nmr structure of card d2 domain Phyre2 PDB 2oda chain B Region: 23 - 51 Aligned: 29 Modelled: 26 Confidence: 11.6% Identity: 24% PDB header:protein binding Chain: B: PDB Molecule:hypothetical protein pspto_2114; PDBTitle: crystal structure of pspto_2114 Phyre2 PDB 5oa3 chain 0 Region: 15 - 46 Aligned: 27 Modelled: 32 Confidence: 10.3% Identity: 30% PDB header:translation Chain: 0: PDB Molecule:eukaryotic translation initiation factor 2d; PDBTitle: human 40s-eif2d-re-initiation complex Phyre2 1 d2gnoa1 2 c4is4G_ 3 c5z58w_ 4 c6g90T_ 5 c2kz3A_ 6 c3tgnA_ 7 d1biha2 8 d2ouwa1 9 c2e5eA_ 10 c2r85B_ 11 c1vw4L_ 12 c5hsmA_ 13 c5b42A_ 14 c4fx0A_ 15 c5yhxH_ 16 c5iooA_ 17 c2wx4C_ 18 c2nplX_ 19 c2odaB_ 20 c5oa30_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87