1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	R	Q	L	L	P	A	L	T	M	L	L	V	F	T	V	I	T	G	I	V	Y	P	L	A	V	T	G	V	G	Q	L	F	F	G	D	Q	A	N	G	A	L	L	E	R	D	G	Q	V	I	G	S	A	H	I	G	Q	Q	F
Secondary structure
SS confidence
Disorder		?																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	A	A	K	Y	F	H	P	R	P	S	S	A	G	D	G	Y	D	A	A	A	S	S	G	S	N	L	G	P	T	N	E	K	L	L	A	A	V	A	E	R	V	T	A	Y	R	K	E	N	N	L	P	A	D	T	L	V	P	V	D
Secondary structure
SS confidence
Disorder				?	?									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?																				?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	V	T	G	S	G	S	G	L	D	P	A	I	S	V	V	N	A	K	L	Q	A	P	R	V	A	Q	A	R	N	I	S	I	R	Q	V	E	R	L	I	E	D	H	T	D	A	R	G	L	G	F	L	G	E	R	A	V	N	V	L
Secondary structure
SS confidence
Disorder																															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.
Sequence		R	L	N	L	A	L	D	R	L
Secondary structure
SS confidence
Disorder									?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 17%) Alpha helix ( 52%) Beta strand ( 4%) TM helix ( 11%) (View membrane topology prediction)

Rank Aligned region

PDB 5mrw chain G Region: 5 - 189 Aligned: 184 Modelled: 185 Confidence: 100.0% Identity: 46% PDB header:hydrolase Chain: G: PDB Molecule:potassium-transporting atpase kdpc subunit; PDBTitle: structure of the kdpfabc complex Phyre2 PDB 4oxq chain B Region: 48 - 148 Aligned: 101 Modelled: 101 Confidence: 73.5% Identity: 17% PDB header:metal binding protein Chain: B: PDB Molecule:manganese abc transporter, periplasmic-binding protein PDBTitle: structure of staphylococcus pseudintermedius metal-binding protein2 sita in complex with zinc Phyre2 PDB 4k3v chain A Region: 61 - 148 Aligned: 85 Modelled: 88 Confidence: 58.7% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:abc superfamily atp binding cassette transporter, binding PDBTitle: structure of staphylococcus aureus mntc Phyre2 PDB 1hq1 chain A Region: 142 - 165 Aligned: 24 Modelled: 24 Confidence: 55.4% Identity: 25% Fold: Signal peptide-binding domain Superfamily: Signal peptide-binding domain Family: Signal peptide-binding domain Phyre2 PDB 1dul chain A Region: 142 - 163 Aligned: 22 Modelled: 22 Confidence: 54.5% Identity: 23% Fold: Signal peptide-binding domain Superfamily: Signal peptide-binding domain Family: Signal peptide-binding domain Phyre2 PDB 1qb2 chain A Region: 142 - 165 Aligned: 24 Modelled: 24 Confidence: 53.3% Identity: 33% Fold: Signal peptide-binding domain Superfamily: Signal peptide-binding domain Family: Signal peptide-binding domain Phyre2 PDB 4akt chain B Region: 131 - 181 Aligned: 51 Modelled: 51 Confidence: 53.1% Identity: 22% PDB header:hydrolase/peptide Chain: B: PDB Molecule:thiazoline oxidase/subtilisin-like protease; PDBTitle: patg macrocyclase in complex with peptide Phyre2 PDB 4ue4 chain C Region: 142 - 163 Aligned: 22 Modelled: 22 Confidence: 51.8% Identity: 27% PDB header:translation Chain: C: PDB Molecule:signal recognition particle protein; PDBTitle: structural basis for targeting and elongation arrest of bacillus2 signal recognition particle Phyre2 PDB 2jqe chain A Region: 142 - 165 Aligned: 24 Modelled: 24 Confidence: 51.4% Identity: 21% PDB header:signaling protein Chain: A: PDB Molecule:signal recognition 54 kda protein; PDBTitle: soution structure of af54 m-domain Phyre2 PDB 4xco chain C Region: 141 - 165 Aligned: 25 Modelled: 25 Confidence: 50.0% Identity: 12% PDB header:rna binding protein Chain: C: PDB Molecule:signal recognition particle 54 kda protein,signal sequence; PDBTitle: signal-sequence induced conformational changes in the signal2 recognition particle Phyre2 PDB 2ffh chain A domain 2 Region: 142 - 163 Aligned: 22 Modelled: 22 Confidence: 49.1% Identity: 27% Fold: Signal peptide-binding domain Superfamily: Signal peptide-binding domain Family: Signal peptide-binding domain Phyre2 PDB 3ipw chain A Region: 134 - 170 Aligned: 37 Modelled: 37 Confidence: 47.0% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica Phyre2 PDB 1qzx chain A domain 2 Region: 142 - 163 Aligned: 22 Modelled: 22 Confidence: 46.2% Identity: 23% Fold: Signal peptide-binding domain Superfamily: Signal peptide-binding domain Family: Signal peptide-binding domain Phyre2 PDB 3e2v chain A Region: 134 - 173 Aligned: 36 Modelled: 40 Confidence: 43.6% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae Phyre2 PDB 3rcm chain A Region: 126 - 173 Aligned: 44 Modelled: 48 Confidence: 43.5% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida Phyre2 PDB 3gg7 chain A Region: 135 - 174 Aligned: 36 Modelled: 40 Confidence: 41.2% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans Phyre2 PDB 1xwy chain A domain 1 Region: 125 - 171 Aligned: 46 Modelled: 47 Confidence: 35.6% Identity: 9% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1j6o chain A Region: 132 - 174 Aligned: 39 Modelled: 43 Confidence: 35.4% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1zzm chain A domain 1 Region: 142 - 175 Aligned: 30 Modelled: 34 Confidence: 28.3% Identity: 7% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 2y1h chain A Region: 142 - 173 Aligned: 28 Modelled: 32 Confidence: 26.1% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) Phyre2 1 c5mrwG_ 2 c4oxqB_ 3 c4k3vA_ 4 d1hq1a_ 5 d1dula_ 6 d1qb2a_ 7 c4aktB_ 8 c4ue4C_ 9 c2jqeA_ 10 c4xcoC_ 11 d2ffha2 12 c3ipwA_ 13 d1qzxa2 14 c3e2vA_ 15 c3rcmA_ 16 c3gg7A_ 17 d1xwya1 18 d1j6oa_ 19 d1zzma1 20 c2y1hA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99