1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		L	C	A	K	P	Y	L	I	D	T	I	A	H	M	A	I	W	D	R	L	V	E	V	A	A	E	Q	H	G	Y	V	T	T	R	D	A	R	D	I	G	V	D	P	V	Q	L	R	L	L	A	G	R	G	R	L	E	R	V	G	R
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	V	Y	R	V	P	V	L	P	R	G	E	H	D	D	L	A	A	A	V	S	W	T	L	G	R	G	V	I	S	H	E	S	A	L	A	L	H	A	L	A	D	V	N	P	S	R	I	H	L	T	V	P	R	N	N	H	P	R	A
Secondary structure
SS confidence
Disorder																																																								?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	G	G	E	L	Y	R	V	H	R	R	D	L	Q	A	A	H	V	T	S	V	D	G	I	P	V	T	T	V	A	R	T	I	K	D	C	V	K	T	G	T	D	P	Y	Q	L	R	A	A	I	E	R	A	E	A	E	G	T	L	R
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
Sequence		R	G	S	A	A	E	L	R	A	A	L	D	E	T	T	A	G	L	R	A	R	P	K	R	A	S	A
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?						?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 11%) Alpha helix ( 48%) Beta strand ( 17%)

Rank Aligned region

PDB 1zel chain A Region: 20 - 188 Aligned: 167 Modelled: 169 Confidence: 98.1% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rv2827c; PDBTitle: crystal structure of rv2827c protein from mycobacterium tuberculosis Phyre2 PDB 3b73 chain A Region: 18 - 66 Aligned: 48 Modelled: 49 Confidence: 93.7% Identity: 25% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phih1 repressor-like protein; PDBTitle: crystal structure of the phih1 repressor-like protein from haloarcula2 marismortui Phyre2 PDB 1zel chain A domain 2 Region: 85 - 188 Aligned: 102 Modelled: 104 Confidence: 88.3% Identity: 17% Fold: Rv2827c C-terminal domain-like Superfamily: Rv2827c C-terminal domain-like Family: Rv2827c C-terminal domain-like Phyre2 PDB 2pjp chain A Region: 12 - 101 Aligned: 86 Modelled: 90 Confidence: 83.1% Identity: 13% PDB header:translation/rna Chain: A: PDB Molecule:selenocysteine-specific elongation factor; PDBTitle: structure of the mrna-binding domain of elongation factor2 selb from e.coli in complex with secis rna Phyre2 PDB 3lmm chain B Region: 14 - 61 Aligned: 48 Modelled: 48 Confidence: 79.3% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the dip2311 protein from corynebacterium2 diphtheriae, northeast structural genomics consortium target cdr35 Phyre2 PDB 1mkm chain A domain 1 Region: 11 - 67 Aligned: 57 Modelled: 57 Confidence: 78.7% Identity: 9% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Transcriptional regulator IclR, N-terminal domain Phyre2 PDB 4j2n chain A Region: 30 - 61 Aligned: 32 Modelled: 32 Confidence: 74.4% Identity: 25% PDB header:viral protein Chain: A: PDB Molecule:gp37; PDBTitle: crystal structure of mycobacteriophage pukovnik xis Phyre2 PDB 4o6j chain A Region: 10 - 66 Aligned: 57 Modelled: 57 Confidence: 72.4% Identity: 16% PDB header:metal binding protein Chain: A: PDB Molecule:iron-dependent transcription repressor related protein; PDBTitle: crystal sturucture of t. acidophilum ider Phyre2 PDB 2kfs chain A Region: 29 - 61 Aligned: 33 Modelled: 33 Confidence: 72.3% Identity: 18% PDB header:dna-binding protein Chain: A: PDB Molecule:conserved hypothetical regulatory protein; PDBTitle: nmr structure of rv2175c Phyre2 PDB 1j5y chain A domain 1 Region: 16 - 68 Aligned: 53 Modelled: 53 Confidence: 71.1% Identity: 11% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Biotin repressor-like Phyre2 PDB 4j2n chain B Region: 30 - 61 Aligned: 32 Modelled: 32 Confidence: 70.8% Identity: 25% PDB header:viral protein Chain: B: PDB Molecule:gp37; PDBTitle: crystal structure of mycobacteriophage pukovnik xis Phyre2 PDB 2o0y chain B Region: 11 - 65 Aligned: 55 Modelled: 55 Confidence: 66.5% Identity: 15% PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator rha1_ro069532 (iclr-family) from rhodococcus sp. Phyre2 PDB 2x4h chain A Region: 10 - 66 Aligned: 57 Modelled: 57 Confidence: 66.2% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:hypothetical protein sso2273; PDBTitle: crystal structure of the hypothetical protein sso2273 from2 sulfolobus solfataricus Phyre2 PDB 2h09 chain A Region: 12 - 66 Aligned: 55 Modelled: 55 Confidence: 65.8% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator mntr; PDBTitle: crystal structure of diphtheria toxin repressor like protein2 from e. coli Phyre2 PDB 3l09 chain B Region: 22 - 66 Aligned: 45 Modelled: 45 Confidence: 64.9% Identity: 27% PDB header:transcription regulator Chain: B: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator2 (jann_22dec04_contig27_revised_gene3569) from jannaschia sp. ccs1 at3 2.81 a resolution Phyre2 PDB 2g7u chain B Region: 9 - 67 Aligned: 58 Modelled: 59 Confidence: 58.4% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:transcriptional regulator; PDBTitle: 2.3 a structure of putative catechol degradative operon regulator from2 rhodococcus sp. rha1 Phyre2 PDB 6ama chain O Region: 30 - 55 Aligned: 26 Modelled: 26 Confidence: 56.9% Identity: 27% PDB header:dna binding protein/dna Chain: O: PDB Molecule:putative dna-binding protein; PDBTitle: structure of s. coelicolor/s. venezuelae bldc-smea-ssfa complex to2 3.09 angstrom Phyre2 PDB 5whm chain B Region: 19 - 67 Aligned: 49 Modelled: 49 Confidence: 55.7% Identity: 12% PDB header:transcription Chain: B: PDB Molecule:iclr family transcriptional regulator; PDBTitle: crystal structure of iclr family transcriptional regulator from2 brucella abortus Phyre2 PDB 5h1a chain C Region: 19 - 66 Aligned: 48 Modelled: 48 Confidence: 51.8% Identity: 21% PDB header:transcription regulator Chain: C: PDB Molecule:iclr transcription factor homolog; PDBTitle: crystal structure of an iclr homolog from microbacterium sp. strain2 hm58-2 Phyre2 PDB 2it0 chain A Region: 12 - 66 Aligned: 55 Modelled: 55 Confidence: 50.6% Identity: 13% PDB header:transcription/dna Chain: A: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii Phyre2 1 c1zelA_ 2 c3b73A_ 3 d1zela2 4 c2pjpA_ 5 c3lmmB_ 6 d1mkma1 7 c4j2nA_ 8 c4o6jA_ 9 c2kfsA_ 10 d1j5ya1 11 c4j2nB_ 12 c2o0yB_ 13 c2x4hA_ 14 c2h09A_ 15 c3l09B_ 16 c2g7uB_ 17 c6amaO_ 18 c5whmB_ 19 c5h1aC_ 20 c2it0A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99