1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	V	D	Y	P	Q	M	A	A	T	R	G	R	I	E	P	A	P	R	R	V	R	G	Y	L	G	H	V	L	V	F	D	T	S	A	A	R	Y	V	W	E	V	P	Y	Y	P	Q	Y	Y	I	P	L	A	D	V	R	M	E	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																																																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	R	D	E	N	H	P	Q	R	V	Q	L	G	P	S	R	L	H	S	L	V	S	A	G	Q	T	H	R	S	A	A	R	V	F	D	V	D	G	D	S	P	V	A	G	T	V	R	F	N	W	D	P	L	R	W	F	E	E	D	E
Secondary structure
SS confidence
Disorder			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	I	Y	G	H	P	R	N	P	Y	Q	R	A	D	A	L	R	S	H	R	H	V	R	V	E	L	D	G	I	V	L	A	D	T	R	S	P	V	L	L	F	E	T	G	I	P	T	R	Y	Y	I	D	P	A	D	I	A	F	E	H
Secondary structure
SS confidence
Disorder					?														?																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	E	P	T	S	T	Q	T	L	C	P	Y	K	G	T	T	S	G	Y	W	S	V	R	V	G	D	A	V	H	R	D	L	A	W	T	Y	H	Y	P	L	P	A	V	A	P	I	A	G	L	V	A	F	Y	N	E	K	V	D	L	T
Secondary structure
SS confidence
Disorder				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.
Sequence		V	D	G	V	A	L	P	R	P	H	T	Q	F	S
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 10%) Alpha helix ( 11%) Beta strand ( 44%)

Rank Aligned region

PDB 3djm chain A Region: 130 - 240 Aligned: 110 Modelled: 111 Confidence: 100.0% Identity: 25% PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein duf427; PDBTitle: crystal structure of a protein of unknown function from duf427 family2 (rsph17029_0682) from rhodobacter sphaeroides 2.4.1 at 2.51 a3 resolution Phyre2 PDB 1w66 chain A domain 1 Region: 32 - 79 Aligned: 46 Modelled: 48 Confidence: 29.9% Identity: 13% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: LplA-like Phyre2 PDB 5hj0 chain C Region: 216 - 243 Aligned: 28 Modelled: 28 Confidence: 22.1% Identity: 18% PDB header:ligase Chain: C: PDB Molecule:kinetochore protein mis18; PDBTitle: crystal structure of mis18 'yippee-like' domain Phyre2 PDB 4b1q chain P Region: 179 - 195 Aligned: 17 Modelled: 17 Confidence: 21.0% Identity: 41% PDB header:toxin Chain: P: PDB Molecule:conotoxin cctx; PDBTitle: nmr structure of the glycosylated conotoxin cctx from conus consors Phyre2 PDB 4l0z chain A Region: 229 - 254 Aligned: 26 Modelled: 26 Confidence: 20.4% Identity: 42% PDB header:transcription/dna Chain: A: PDB Molecule:runt-related transcription factor 1; PDBTitle: crystal structure of runx1 and ets1 bound to tcr alpha promoter2 (crystal form 2) Phyre2 PDB 2mjc chain A Region: 187 - 195 Aligned: 9 Modelled: 9 Confidence: 14.1% Identity: 67% PDB header:metal binding protein Chain: A: PDB Molecule:eukaryotic translation initiation factor 3 subunit g; PDBTitle: zn-binding domain of eukaryotic translation initiation factor 3,2 subunit g Phyre2 PDB 3ico chain A Region: 104 - 148 Aligned: 45 Modelled: 45 Confidence: 12.8% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from mycobacterium2 tuberculosis Phyre2 PDB 1w9s chain A Region: 127 - 157 Aligned: 26 Modelled: 31 Confidence: 12.0% Identity: 31% Fold: Galactose-binding domain-like Superfamily: Galactose-binding domain-like Family: Family 6 carbohydrate binding module, CBM6 Phyre2 PDB 5o60 chain X Region: 223 - 249 Aligned: 27 Modelled: 27 Confidence: 11.7% Identity: 33% PDB header:ribosome Chain: X: PDB Molecule:50s ribosomal protein l27; PDBTitle: structure of the 50s large ribosomal subunit from mycobacterium2 smegmatis Phyre2 PDB 1z8r chain A Region: 103 - 119 Aligned: 16 Modelled: 17 Confidence: 11.7% Identity: 44% PDB header:hydrolase Chain: A: PDB Molecule:coxsackievirus b4 polyprotein; PDBTitle: 2a cysteine proteinase from human coxsackievirus b4 (strain2 jvb / benschoten / new york / 51) Phyre2 PDB 4lmg chain D Region: 148 - 204 Aligned: 33 Modelled: 34 Confidence: 10.1% Identity: 33% PDB header:transcription activator/dna Chain: D: PDB Molecule:iron-regulated transcriptional activator aft2; PDBTitle: crystal structure of aft2 in complex with dna Phyre2 PDB 4azz chain B Region: 131 - 157 Aligned: 27 Modelled: 27 Confidence: 10.1% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:levanase; PDBTitle: carbohydrate binding module cbm66 from bacillus subtilis Phyre2 PDB 4e6n chain B Region: 66 - 86 Aligned: 21 Modelled: 21 Confidence: 9.7% Identity: 19% PDB header:protein binding Chain: B: PDB Molecule:methyltransferase type 12; PDBTitle: crystal structure of bacterial pnkp-c/hen1-n heterodimer Phyre2 PDB 6osw chain A Region: 121 - 143 Aligned: 23 Modelled: 23 Confidence: 9.3% Identity: 13% PDB header:cell cycle Chain: A: PDB Molecule:forkhead box m1; PDBTitle: an order-to-disorder structural switch activates the foxm12 transcription factor Phyre2 PDB 4caw chain A Region: 199 - 233 Aligned: 35 Modelled: 35 Confidence: 9.1% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:glycylpeptide n-tetradecanoyltransferase; PDBTitle: crystal structure of aspergillus fumigatus n-myristoyl2 transferase in complex with myristoyl coa and a pyrazole3 sulphonamide ligand Phyre2 PDB 5c17 chain A Region: 115 - 151 Aligned: 29 Modelled: 35 Confidence: 8.9% Identity: 24% PDB header:lyase Chain: A: PDB Molecule:merb2; PDBTitle: crystal structure of the mercury-bound form of merb2 Phyre2 PDB 2kd2 chain A Region: 229 - 247 Aligned: 19 Modelled: 19 Confidence: 8.9% Identity: 16% PDB header:apoptosis Chain: A: PDB Molecule:fas apoptotic inhibitory molecule 1; PDBTitle: nmr structure of faim-ctd Phyre2 PDB 1txn chain A Region: 121 - 130 Aligned: 10 Modelled: 8 Confidence: 7.9% Identity: 40% Fold: Coproporphyrinogen III oxidase Superfamily: Coproporphyrinogen III oxidase Family: Coproporphyrinogen III oxidase Phyre2 PDB 1ne7 chain A Region: 104 - 148 Aligned: 45 Modelled: 45 Confidence: 7.8% Identity: 16% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: NagB-like Phyre2 PDB 1m7j chain A domain 2 Region: 103 - 153 Aligned: 39 Modelled: 43 Confidence: 7.8% Identity: 26% Fold: Composite domain of metallo-dependent hydrolases Superfamily: Composite domain of metallo-dependent hydrolases Family: D-aminoacylase Phyre2 1 c3djmA_ 2 d1w66a1 3 c5hj0C_ 4 c4b1qP_ 5 c4l0zA_ 6 c2mjcA_ 7 c3icoA_ 8 d1w9sa_ 9 c5o60X_ 10 c1z8rA_ 11 c4lmgD_ 12 c4azzB_ 13 c4e6nB_ 14 c6oswA_ 15 c4cawA_ 16 c5c17A_ 17 c2kd2A_ 18 d1txna_ 19 d1ne7a_ 20 d1m7ja2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51