1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	A	P	A	A	L	R	V	R	G	S	S	S	P	R	V	A	L	A	L	G	S	G	G	A	R	G	Y	A	H	I	G	V	I	Q	A	L	R	E	R	G	Y	D	I	V	G	I	A	G	S	S	M	G	A	V	V	G	G	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	A	A	G	R	L	D	E	F	A	H	W	A	K	S	L	T	Q	R	T	I	L	R	L	L	D	P	S	I	S	A	A	G	I	L	R	A	E	K	I	L	D	A	V	R	D	I	V	G	P	V	A	I	E	Q	L	P	I	P	Y
Secondary structure
SS confidence
Disorder																					?						?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	A	V	A	T	D	L	L	A	G	K	S	V	W	F	Q	R	G	P	L	D	A	A	I	R	A	S	I	A	I	P	G	V	I	A	P	H	E	V	D	G	R	L	L	A	D	G	G	I	L	D	P	L	P	M	A	P	I	A	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	N	A	D	L	T	I	A	V	S	L	N	G	S	E	A	G	P	A	R	D	A	E	P	N	V	T	A	E	W	L	N	R	M	V	R	S	T	S	A	L	F	D	V	S	A	A	R	S	L	L	D	R	P	T	A	R	A	V	L
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?	?	?	?																								?									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	R	F	G	A	A	A	A	E	S	D	S	W	S	Q	A	P	E	I	E	Q	R	P	A	G	P	P	A	D	R	E	E	A	A	D	T	P	G	L	P	K	M	G	S	F	E	V	M	N	R	T	I	D	I	A	Q	S	A	L	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?		?	?		?		?			?	?	?	?	?	?	?		?	?		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	H	T	L	A	G	Y	P	A	D	L	L	I	E	V	P	R	S	T	C	R	S	L	E	F	H	R	A	V	E	V	I	A	V	G	R	A	L	A	T	Q	A	L	E	A	F	E	I	D	D	D	E	S	A	A	A	T	I	E	G
Secondary structure
SS confidence
Disorder																																																		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 24%) Alpha helix ( 53%) Beta strand ( 13%) TM helix ( 4%) (View membrane topology prediction)

Rank Aligned region

PDB 5fya chain A Region: 15 - 349 Aligned: 251 Modelled: 255 Confidence: 100.0% Identity: 38% PDB header:hydrolase Chain: A: PDB Molecule:patatin-like protein, plpd; PDBTitle: cubic crystal of the native plpd Phyre2 PDB 4akf chain A Region: 12 - 353 Aligned: 267 Modelled: 267 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:vipd; PDBTitle: crystal structure of vipd from legionella pneumophila Phyre2 PDB 4qmk chain B Region: 12 - 179 Aligned: 168 Modelled: 168 Confidence: 100.0% Identity: 26% PDB header:toxin Chain: B: PDB Molecule:type iii secretion system effector protein exou; PDBTitle: crystal structure of type iii effector protein exou (exou) Phyre2 PDB 3tu3 chain B Region: 12 - 192 Aligned: 179 Modelled: 181 Confidence: 100.0% Identity: 27% PDB header:toxin/toxin chaperone Chain: B: PDB Molecule:exou; PDBTitle: 1.92 angstrom resolution crystal structure of the full-length spcu in2 complex with full-length exou from the type iii secretion system of3 pseudomonas aeruginosa Phyre2 PDB 4akx chain B Region: 12 - 191 Aligned: 172 Modelled: 180 Confidence: 100.0% Identity: 24% PDB header:transport protein Chain: B: PDB Molecule:exou; PDBTitle: structure of the heterodimeric complex exou-spcu from the type iii2 secretion system (t3ss) of pseudomonas aeruginosa Phyre2 PDB 1oxw chain A Region: 13 - 353 Aligned: 277 Modelled: 273 Confidence: 100.0% Identity: 17% Fold: FabD/lysophospholipase-like Superfamily: FabD/lysophospholipase-like Family: Patatin Phyre2 PDB 6aun chain B Region: 5 - 349 Aligned: 258 Modelled: 271 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:pla2g6, ipla2beta; PDBTitle: calcium-independent phospholipase a2 beta Phyre2 PDB 1cjy chain A domain 2 Region: 11 - 194 Aligned: 177 Modelled: 184 Confidence: 99.4% Identity: 21% Fold: FabD/lysophospholipase-like Superfamily: FabD/lysophospholipase-like Family: Lysophospholipase Phyre2 PDB 5izr chain C Region: 15 - 196 Aligned: 175 Modelled: 182 Confidence: 99.1% Identity: 22% PDB header:hydrolase/hydrolase inhibitor Chain: C: PDB Molecule:cytosolic phospholipase a2 delta; PDBTitle: human givd cytosolic phospholipase a2 in complex with methyl gamma-2 linolenyl fluorophosphonate inhibitor and terbium chloride Phyre2 PDB 1cjy chain B Region: 11 - 61 Aligned: 51 Modelled: 51 Confidence: 98.2% Identity: 29% PDB header:hydrolase Chain: B: PDB Molecule:protein (cytosolic phospholipase a2); PDBTitle: human cytosolic phospholipase a2 Phyre2 PDB 4rr5 chain A Region: 29 - 125 Aligned: 95 Modelled: 97 Confidence: 92.6% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: the crystal structure of synechocystis sp. pcc 6803 malonyl-coa: acp2 transacylase Phyre2 PDB 4mz0 chain B Region: 2 - 62 Aligned: 61 Modelled: 61 Confidence: 91.8% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:curl; PDBTitle: structure of a ketosynthase-acyltransferase di-domain from module curl2 of the curacin a polyketide synthase Phyre2 PDB 1mla chain A domain 1 Region: 29 - 62 Aligned: 34 Modelled: 34 Confidence: 90.0% Identity: 24% Fold: FabD/lysophospholipase-like Superfamily: FabD/lysophospholipase-like Family: FabD-like Phyre2 PDB 5ydm chain A Region: 26 - 62 Aligned: 37 Modelled: 37 Confidence: 90.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:pks; PDBTitle: the crystal structure of the acyl transferase domain of spnd complex2 with benzylmalonyl Phyre2 PDB 6a4t chain B Region: 18 - 59 Aligned: 42 Modelled: 42 Confidence: 89.6% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:peptidase e; PDBTitle: crystal structure of peptidase e from deinococcus radiodurans r1 Phyre2 PDB 4amm chain A Region: 29 - 62 Aligned: 34 Modelled: 34 Confidence: 89.2% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:dyne8; PDBTitle: crystal structure of the acyltransferase domain of the2 iterative polyketide synthase in enediyne biosynthesis3 reveals the molecular basis of substrate specificity Phyre2 PDB 6iyt chain A Region: 26 - 62 Aligned: 37 Modelled: 37 Confidence: 89.1% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:type i modular polyketide synthase; PDBTitle: crystal structure of the acyltransferase domain from second module 142 of salinomycin polyketide synthase Phyre2 PDB 3im8 chain A Region: 29 - 62 Aligned: 34 Modelled: 34 Confidence: 88.9% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:malonyl acyl carrier protein transacylase; PDBTitle: crystal structure of mcat from streptococcus pneumoniae Phyre2 PDB 3ptw chain A Region: 26 - 62 Aligned: 37 Modelled: 37 Confidence: 88.8% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:malonyl coa-acyl carrier protein transacylase; PDBTitle: crystal structure of malonyl coa-acyl carrier protein transacylase2 from clostridium perfringens atcc 13124 Phyre2 PDB 2jfk chain D Region: 29 - 62 Aligned: 34 Modelled: 34 Confidence: 88.2% Identity: 35% PDB header:transferase Chain: D: PDB Molecule:fatty acid synthase; PDBTitle: structure of the mat domain of human fas with malonyl-coa Phyre2 1 c5fyaA_ 2 c4akfA_ 3 c4qmkB_ 4 c3tu3B_ 5 c4akxB_ 6 d1oxwa_ 7 c6aunB_ 8 d1cjya2 9 c5izrC_ 10 c1cjyB_ 11 c4rr5A_ 12 c4mz0B_ 13 d1mlaa1 14 c5ydmA_ 15 c6a4tB_ 16 c4ammA_ 17 c6iytA_ 18 c3im8A_ 19 c3ptwA_ 20 c2jfkD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159