1

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10

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20

.

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30

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40

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50

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.

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.

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.

.

60

Sequence

V

R

P

S

R

Y

A

P

L

L

C

A

M

V

L

A

L

A

W

L

S

A

V

A

G

C

S

R

G

G

S

S

K

A

G

R

S

S

S

V

A

G

T

L

P

A

G

V

V

G

V

S

P

A

G

V

T

T

R

V

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

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.

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70

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80

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90

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.

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100

.

.

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.

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110

.

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.

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.

.

.

.

.

120

Sequence

D

A

P

A

E

S

T

E

E

E

Y

Y

Q

A

C

H

A

A

R

L

W

M

D

A

Q

P

G

S

G

E

S

L

I

E

P

Y

L

A

V

V

Q

A

S

P

S

G

V

A

G

S

W

H

I

R

W

A

A

L

T

P

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

?

Disorder confidence

.

.

.

.

.

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.

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130

.

.

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.

.

.

.

.

.

Sequence

A

R

Q

A

A

V

I

V

A

A

R

A

A

A

N

A

E

C

G

Secondary structure

SS confidence

Disorder

?

?

?

?

?

?

?

?

Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 53%) Alpha helix ( 51%) Beta strand ( 5%)

Rank Aligned region

PDB 3btp chain A Region: 121 - 129 Aligned: 9 Modelled: 9 Confidence: 22.2% Identity: 89% PDB header:dna binding protein, chaperone Chain: A: PDB Molecule:single-strand dna-binding protein; PDBTitle: crystal structure of agrobacterium tumefaciens vire2 in complex with2 its chaperone vire1: a novel fold and implications for dna binding Phyre2 PDB 3ez0 chain D Region: 79 - 114 Aligned: 36 Modelled: 36 Confidence: 12.3% Identity: 19% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein with ferritin-like fold; PDBTitle: crystal structure of protein of unknown function with ferritin-like2 fold (yp_832262.1) from arthrobacter sp. fb24 at 2.33 a resolution Phyre2 PDB 2i09 chain A domain 2 Region: 69 - 86 Aligned: 18 Modelled: 18 Confidence: 11.5% Identity: 33% Fold: DeoB insert domain-like Superfamily: DeoB insert domain-like Family: DeoB insert domain-like Phyre2 PDB 2hro chain A Region: 67 - 86 Aligned: 20 Modelled: 20 Confidence: 10.3% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of the full-lenght enzyme i of the pts system from2 staphylococcus carnosus Phyre2 PDB 3sgg chain A Region: 70 - 117 Aligned: 46 Modelled: 48 Confidence: 9.4% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:hypothetical hydrolase; PDBTitle: crystal structure of a putative hydrolase (bt_2193) from bacteroides2 thetaiotaomicron vpi-5482 at 1.25 a resolution Phyre2 PDB 2rov chain A Region: 93 - 122 Aligned: 29 Modelled: 30 Confidence: 9.1% Identity: 10% PDB header:transferase Chain: A: PDB Molecule:rho-associated protein kinase 2; PDBTitle: the split ph domain of rock ii Phyre2 PDB 4zv4 chain C Region: 78 - 124 Aligned: 46 Modelled: 47 Confidence: 8.7% Identity: 20% PDB header:translation Chain: C: PDB Molecule:tse6; PDBTitle: structure of tse6 in complex with ef-tu Phyre2 PDB 2dzj chain A Region: 111 - 124 Aligned: 14 Modelled: 14 Confidence: 8.3% Identity: 29% PDB header:sugar binding protein Chain: A: PDB Molecule:synaptic glycoprotein sc2; PDBTitle: 2dzj/solution structure of the n-terminal ubiquitin-like2 domain in human synaptic glycoprotein sc2 Phyre2 PDB 1bak chain A Region: 84 - 122 Aligned: 36 Modelled: 39 Confidence: 7.7% Identity: 17% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Pleckstrin-homology domain (PH domain) Phyre2 PDB 2ffu chain A Region: 76 - 84 Aligned: 9 Modelled: 9 Confidence: 7.5% Identity: 56% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 2; PDBTitle: crystal structure of human ppgalnact-2 complexed with udp and ea2 Phyre2 PDB 6iwq chain E Region: 76 - 84 Aligned: 9 Modelled: 9 Confidence: 7.5% Identity: 22% PDB header:transferase Chain: E: PDB Molecule:n-acetylgalactosaminyltransferase 7; PDBTitle: crystal structure of galnac-t7 with mn2+ Phyre2 PDB 2dhk chain A Region: 84 - 122 Aligned: 37 Modelled: 39 Confidence: 6.5% Identity: 22% PDB header:immune system Chain: A: PDB Molecule:tbc1 domain family member 2; PDBTitle: solution structure of the ph domain of tbc1 domain family2 member 2 protein from human Phyre2 PDB 2k47 chain A Region: 66 - 75 Aligned: 10 Modelled: 10 Confidence: 6.5% Identity: 20% PDB header:replication Chain: A: PDB Molecule:phosphoprotein; PDBTitle: solution structure of the c-terminal n-rna binding domain2 of the vesicular stomatitis virus phosphoprotein Phyre2 PDB 2hwg chain A Region: 67 - 86 Aligned: 20 Modelled: 20 Confidence: 6.4% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the phosphoenolpyruvate:sugar2 phosphotransferase system Phyre2 PDB 5us5 chain B Region: 82 - 99 Aligned: 18 Modelled: 18 Confidence: 6.2% Identity: 17% PDB header:structural genomics Chain: B: PDB Molecule:upf0297 protein ef_1202; PDBTitle: solution structure of the ireb homodimer Phyre2 PDB 5ola chain D Region: 94 - 123 Aligned: 30 Modelled: 30 Confidence: 6.1% Identity: 30% PDB header:transcription Chain: D: PDB Molecule:transcription elongation factor, mitochondrial; PDBTitle: structure of mitochondrial transcription elongation complex in complex2 with elongation factor tefm Phyre2 PDB 3ftq chain A Region: 65 - 80 Aligned: 16 Modelled: 16 Confidence: 5.6% Identity: 31% PDB header:cell cycle Chain: A: PDB Molecule:septin-2; PDBTitle: crystal structure of septin 2 in complex with gppnhp and2 mg2+ Phyre2 PDB 5mr1 chain A Region: 91 - 119 Aligned: 29 Modelled: 29 Confidence: 5.4% Identity: 17% PDB header:signaling protein Chain: A: PDB Molecule:interactor protein for cytohesin exchange factors 1; PDBTitle: crystal structure of the pleckstrin homology domain of interactor2 protein for cytohesin exchange factors 1 (ipcef1) Phyre2 PDB 5ifg chain B Region: 67 - 96 Aligned: 30 Modelled: 30 Confidence: 5.3% Identity: 23% PDB header:hydrolase/antitoxin Chain: B: PDB Molecule:antitoxin higa; PDBTitle: crystal structure of higa-higb complex from e. coli Phyre2 1 c3btpA_ 2 c3ez0D_ 3 d2i09a2 4 c2hroA_ 5 c3sggA_ 6 c2rovA_ 7 c4zv4C_ 8 c2dzjA_ 9 d1baka_ 10 c2ffuA_ 11 c6iwqE_ 12 c2dhkA_ 13 c2k47A_ 14 c2hwgA_ 15 c5us5B_ 16 c5olaD_ 17 c3ftqA_ 18 c5mr1A_ 19 c5ifgB_