1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	G	A	Q	P	F	I	G	S	E	A	L	A	A	G	L	I	S	W	H	E	L	G	K	Y	Y	T	A	I	M	P	N	V	Y	L	D	K	R	L	K	P	S	L	R	Q	R	V	I	A	A	W	L	W	S	G	R	K	G	V	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	G	A	S	A	S	A	L	H	G	A	K	W	V	D	D	H	A	L	V	E	L	I	W	R	N	A	R	A	P	N	G	V	R	T	K	D	E	L	L	L	D	G	E	V	Q	R	L	C	G	L	T	V	T	T	V	E	R	T	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	D	L	G	R	R	P	P	L	G	Q	A	I	T	R	L	D	A	L	A	N	A	T	D	F	K	I	N	D	V	R	E	L	A	R	K	H	P	H	T	R	G	L	R	Q	L	D	K	A	L	D	L	V	D	P	G	A	Q	S	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	E	T	W	L	R	L	L	L	I	N	A	G	F	P	R	P	S	T	Q	I	P	L	L	G	V	Y	G	H	P	K	Y	F	L	D	M	G	W	E	D	I	M	L	A	V	E	Y	D	G	E	Q	H	R	L	S	R	D	Q	F	V
Secondary structure
SS confidence
Disorder																																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.
Sequence		K	D	V	E	R	L	E	Y	I	R	R	A	G	W	T	H	I	R	V	L	A	D	H	K	G	P	D	V	V	R	R	V	R	Q	A	W	D	T	L	T	S	R	R
Secondary structure
SS confidence
Disorder																																									?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 44%) Beta strand ( 21%)

Rank Aligned region

PDB 3r3p chain B Region: 178 - 281 Aligned: 96 Modelled: 104 Confidence: 99.6% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:mobile intron protein; PDBTitle: homing endonuclease i-bth0305i catalytic domain Phyre2 PDB 3hrl chain A Region: 177 - 279 Aligned: 86 Modelled: 103 Confidence: 99.3% Identity: 29% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:endonuclease-like protein; PDBTitle: crystal structure of a putative endonuclease-like protein (ngo0050)2 from neisseria gonorrhoeae Phyre2 PDB 1cw0 chain A Region: 176 - 278 Aligned: 96 Modelled: 103 Confidence: 99.3% Identity: 14% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Very short patch repair (VSR) endonuclease Phyre2 PDB 1vsr chain A Region: 181 - 278 Aligned: 91 Modelled: 98 Confidence: 98.0% Identity: 15% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Very short patch repair (VSR) endonuclease Phyre2 PDB 4oq2 chain A Region: 196 - 282 Aligned: 86 Modelled: 87 Confidence: 97.3% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease pvurts1 i; PDBTitle: 5hmc specific restriction endonuclease pvurts1i Phyre2 PDB 4par chain C Region: 196 - 279 Aligned: 82 Modelled: 84 Confidence: 96.9% Identity: 24% PDB header:dna binding protein/dna Chain: C: PDB Molecule:uncharacterized protein abasi; PDBTitle: the 5-hydroxymethylcytosine-specific restriction enzyme abasi in a2 complex with product-like dna Phyre2 PDB 6rdu chain 2 Region: 205 - 261 Aligned: 57 Modelled: 57 Confidence: 94.8% Identity: 11% PDB header:proton transport Chain: 2: PDB Molecule:asa-2: polytomella f-atp synthase associated subunit 2; PDBTitle: cryo-em structure of polytomella f-atp synthase, rotary substate 1e,2 monomer-masked refinement Phyre2 PDB 1zel chain A Region: 7 - 158 Aligned: 147 Modelled: 152 Confidence: 91.0% Identity: 20% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein rv2827c; PDBTitle: crystal structure of rv2827c protein from mycobacterium tuberculosis Phyre2 PDB 1zel chain A domain 2 Region: 41 - 158 Aligned: 115 Modelled: 118 Confidence: 82.0% Identity: 23% Fold: Rv2827c C-terminal domain-like Superfamily: Rv2827c C-terminal domain-like Family: Rv2827c C-terminal domain-like Phyre2 PDB 1m0d chain A Region: 179 - 251 Aligned: 65 Modelled: 73 Confidence: 80.7% Identity: 22% Fold: Restriction endonuclease-like Superfamily: Restriction endonuclease-like Family: Endonuclease I (Holliday junction resolvase) Phyre2 PDB 4p6i chain B Region: 19 - 114 Aligned: 74 Modelled: 76 Confidence: 27.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:crispr-associated endoribonuclease cas2; PDBTitle: crystal structure of the cas1-cas2 complex from escherichia coli Phyre2 PDB 4gqz chain B Region: 194 - 229 Aligned: 36 Modelled: 35 Confidence: 21.3% Identity: 22% PDB header:metal binding protein Chain: B: PDB Molecule:putative periplasmic or exported protein; PDBTitle: crystal structure of s.cuep Phyre2 PDB 2fcl chain A domain 1 Region: 57 - 82 Aligned: 26 Modelled: 26 Confidence: 16.8% Identity: 19% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: TM1012-like Phyre2 PDB 3dup chain B Region: 107 - 162 Aligned: 56 Modelled: 54 Confidence: 13.8% Identity: 7% PDB header:hydrolase Chain: B: PDB Molecule:mutt/nudix family protein; PDBTitle: crystal structure of mutt/nudix family hydrolase from rhodospirillum2 rubrum atcc 11170 Phyre2 PDB 2uwj chain G Region: 114 - 194 Aligned: 77 Modelled: 81 Confidence: 11.5% Identity: 14% PDB header:chaperone Chain: G: PDB Molecule:type iii export protein pscg; PDBTitle: structure of the heterotrimeric complex which regulates type iii2 secretion needle formation Phyre2 PDB 4mak chain A Region: 19 - 61 Aligned: 42 Modelled: 43 Confidence: 11.1% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:crispr-associated endoribonuclease cas2; PDBTitle: crystal structure of a putative ssrna endonuclease cas2, crispr2 adaptation protein from e.coli Phyre2 PDB 2fuk chain A domain 1 Region: 193 - 259 Aligned: 67 Modelled: 67 Confidence: 10.1% Identity: 19% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Atu1826-like Phyre2 PDB 3wbz chain D Region: 215 - 233 Aligned: 19 Modelled: 19 Confidence: 9.9% Identity: 16% PDB header:transferase Chain: D: PDB Molecule:likely histidyl trna-specific guanylyltransferase; PDBTitle: crystal structure of c. albicans trna(his) guanylyltransferase (thg1)2 with atp Phyre2 PDB 5xox chain D Region: 215 - 233 Aligned: 19 Modelled: 19 Confidence: 9.8% Identity: 21% PDB header:transferase Chain: D: PDB Molecule:trna(his) guanylyltransferase; PDBTitle: crystal structure of trna(his) guanylyltranserase from saccharomyces2 cerevisiae Phyre2 PDB 3otb chain B Region: 215 - 233 Aligned: 19 Modelled: 19 Confidence: 9.5% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:trna(his) guanylyltransferase; PDBTitle: crystal structure of human trnahis guanylyltransferase (thg1) - dgtp2 complex Phyre2 1 c3r3pB_ 2 c3hrlA_ 3 d1cw0a_ 4 d1vsra_ 5 c4oq2A_ 6 c4parC_ 7 c6rdu2_ 8 c1zelA_ 9 d1zela2 10 d1m0da_ 11 c4p6iB_ 12 c4gqzB_ 13 d2fcla1 14 c3dupB_ 15 c2uwjG_ 16 c4makA_ 17 d2fuka1 18 c3wbzD_ 19 c5xoxD_ 20 c3otbB_ 21 22 23 24 25 26 27 28 29