1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	E	I	I	P	P	R	L	K	E	P	L	Y	R	L	Y	E	L	R	L	R	Q	G	L	A	A	S	K	S	D	L	P	R	H	I	A	V	L	C	D	G	N	R	R	W	A	R	S	A	G	Y	D	D	V	S	Y	G	Y	R	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?																			?	?	?	?	?	?	?																?			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	A	A	K	I	A	E	M	L	R	W	C	H	E	A	G	I	E	L	A	T	V	Y	L	L	S	T	E	N	L	Q	R	D	P	D	E	L	A	A	L	I	E	I	I	T	D	V	V	E	E	I	C	A	P	A	N	H	W	S	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	T	V	G	D	L	G	L	I	G	E	E	P	A	R	R	L	R	G	A	V	E	S	T	P	E	V	A	S	F	H	V	N	V	A	V	G	Y	G	G	R	R	E	I	V	D	A	V	R	A	L	L	S	K	E	L	A	N	G	A
Secondary structure
SS confidence
Disorder																																																											?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	A	E	E	L	V	D	A	V	T	V	E	G	I	S	E	N	L	Y	T	S	G	Q	P	D	P	D	L	V	I	R	T	S	G	E	Q	R	L	S	G	F	L	L	W	Q	S	A	Y	S	E	M	W	F	T	E	A	H	W	P	A
Secondary structure
SS confidence
Disorder		?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.
Sequence		F	R	H	V	D	F	L	R	A	L	R	D	Y	S	A	R	H	R	S	Y	G	R
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 12%) Alpha helix ( 50%) Beta strand ( 13%)

Rank Aligned region

PDB 2vg2 chain C Region: 27 - 262 Aligned: 231 Modelled: 236 Confidence: 100.0% Identity: 35% PDB header:transferase Chain: C: PDB Molecule:undecaprenyl pyrophosphate synthetase; PDBTitle: rv2361 with ipp Phyre2 PDB 4h8e chain A Region: 27 - 262 Aligned: 231 Modelled: 236 Confidence: 100.0% Identity: 30% PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:undecaprenyl pyrophosphate synthase; PDBTitle: structure of s. aureus undecaprenyl diphosphate synthase in complex2 with fpp and sulfate Phyre2 PDB 2vfw chain B Region: 30 - 256 Aligned: 227 Modelled: 227 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: B: PDB Molecule:short-chain z-isoprenyl diphosphate synthetase; PDBTitle: rv1086 native Phyre2 PDB 5hc7 chain A Region: 30 - 256 Aligned: 222 Modelled: 227 Confidence: 100.0% Identity: 32% PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:prenyltransference for protein; PDBTitle: crystal structure of lavandulyl diphosphate synthase from lavandula x2 intermedia in complex with s-thiolo-isopentenyldiphosphate Phyre2 PDB 4q9m chain A Region: 29 - 257 Aligned: 224 Modelled: 229 Confidence: 100.0% Identity: 33% PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:isoprenyl transferase; PDBTitle: crystal structure of upps in complex with fpp and an allosteric2 inhibitor Phyre2 PDB 5hxp chain A Region: 27 - 261 Aligned: 221 Modelled: 235 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:(2z,6z)-farnesyl diphosphate synthase, chloroplastic; PDBTitle: crystal structure of z,z-farnesyl diphosphate synthase (d71m, e75a and2 h103y mutants) complexed with ipp Phyre2 PDB 5guk chain A Region: 34 - 261 Aligned: 211 Modelled: 217 Confidence: 100.0% Identity: 28% PDB header:biosynthetic protein Chain: A: PDB Molecule:cyclolavandulyl diphosphate synthase; PDBTitle: crystal structure of apo form of cyclolavandulyl diphosphate synthase2 (clds) from streptomyces sp. cl190 Phyre2 PDB 1ueh chain A Region: 29 - 257 Aligned: 211 Modelled: 216 Confidence: 100.0% Identity: 33% Fold: Undecaprenyl diphosphate synthase Superfamily: Undecaprenyl diphosphate synthase Family: Undecaprenyl diphosphate synthase Phyre2 PDB 6acs chain A Region: 26 - 262 Aligned: 219 Modelled: 223 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:ditrans,polycis-undecaprenyl-diphosphate synthase ((2e,6e)- PDBTitle: poly-cis-prenyltransferase Phyre2 PDB 5xk9 chain F Region: 31 - 256 Aligned: 209 Modelled: 224 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: F: PDB Molecule:undecaprenyl diphosphate synthase; PDBTitle: crystal structure of isosesquilavandulyl diphosphate synthase from2 streptomyces sp. strain cnh-189 in complex with gspp and dmapp Phyre2 PDB 1jp3 chain A Region: 29 - 257 Aligned: 212 Modelled: 229 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:undecaprenyl pyrophosphate synthase; PDBTitle: structure of e.coli undecaprenyl pyrophosphate synthase Phyre2 PDB 1f75 chain A Region: 27 - 256 Aligned: 213 Modelled: 230 Confidence: 100.0% Identity: 30% Fold: Undecaprenyl diphosphate synthase Superfamily: Undecaprenyl diphosphate synthase Family: Undecaprenyl diphosphate synthase Phyre2 PDB 3ugs chain B Region: 30 - 262 Aligned: 205 Modelled: 218 Confidence: 100.0% Identity: 30% PDB header:transferase Chain: B: PDB Molecule:undecaprenyl pyrophosphate synthase; PDBTitle: crystal structure of a probable undecaprenyl diphosphate synthase2 (upps) from campylobacter jejuni Phyre2 PDB 2d2r chain A Region: 32 - 258 Aligned: 211 Modelled: 227 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:undecaprenyl pyrophosphate synthase; PDBTitle: crystal structure of helicobacter pylori undecaprenyl pyrophosphate2 synthase Phyre2 PDB 6jcn chain B Region: 30 - 257 Aligned: 207 Modelled: 221 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:dehydrodolichyl diphosphate synthase complex subunit nus1; PDBTitle: yeast dehydrodolichyl diphosphate synthase complex subunit nus1 Phyre2 PDB 4cmx chain B Region: 21 - 253 Aligned: 220 Modelled: 232 Confidence: 99.3% Identity: 18% PDB header:nuclear protein Chain: B: PDB Molecule:rv3378c; PDBTitle: crystal structure of rv3378c Phyre2 PDB 3cpr chain B Region: 62 - 174 Aligned: 103 Modelled: 111 Confidence: 70.0% Identity: 13% PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution Phyre2 PDB 3s5o chain A Region: 62 - 175 Aligned: 104 Modelled: 112 Confidence: 64.1% Identity: 13% PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate Phyre2 PDB 5ak1 chain A Region: 61 - 111 Aligned: 51 Modelled: 51 Confidence: 62.7% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate binding family 6; PDBTitle: the penta-modular cellulosomal arabinoxylanase ctxyl5a2 structure as revealed by x-ray crystallography Phyre2 PDB 3flu chain D Region: 62 - 173 Aligned: 102 Modelled: 112 Confidence: 58.2% Identity: 15% PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis Phyre2 1 c2vg2C_ 2 c4h8eA_ 3 c2vfwB_ 4 c5hc7A_ 5 c4q9mA_ 6 c5hxpA_ 7 c5gukA_ 8 d1ueha_ 9 c6acsA_ 10 c5xk9F_ 11 c1jp3A_ 12 d1f75a_ 13 c3ugsB_ 14 c2d2rA_ 15 c6jcnB_ 16 c4cmxB_ 17 c3cprB_ 18 c3s5oA_ 19 c5ak1A_ 20 c3fluD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99