1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Y	L	P	W	G	V	V	L	A	G	G	A	N	G	F	G	A	G	A	Y	Q	T	G	T	I	C	E	V	S	T	Q	I	A	V	R	L	P	D	E	I	V	A	F	I	D	D	E	V	R	G	Q	H	A	R	S	R	A	A	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?											?														?																		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.
Sequence		V	L	R	A	L	E	R	E	R	R	R	R	L	A	E	R	D	A	E	I	L	A	T	N	T	S	A	T	G	D	L	D	T	L	A	G	H	C	A	R	T	A	L	D	I	D
Secondary structure
SS confidence
Disorder																	?	?					?	?		?	?	?	?	?											?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 29%) Alpha helix ( 53%) Beta strand ( 14%)

Rank Aligned region

PDB 3kxe chain D Region: 35 - 92 Aligned: 58 Modelled: 58 Confidence: 82.0% Identity: 34% PDB header:protein binding Chain: D: PDB Molecule:antitoxin protein pard-1; PDBTitle: a conserved mode of protein recognition and binding in a2 pard-pare toxin-antitoxin complex Phyre2 PDB 5ceg chain C Region: 32 - 80 Aligned: 49 Modelled: 49 Confidence: 75.9% Identity: 12% PDB header:toxin Chain: C: PDB Molecule:addiction module antidote protein, copg/arc/metj family; PDBTitle: x-ray structure of toxin/anti-toxin complex from mesorhizobium2 opportunistum Phyre2 PDB 2hza chain A domain 1 Region: 33 - 75 Aligned: 43 Modelled: 43 Confidence: 47.7% Identity: 12% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 2bj7 chain A domain 1 Region: 33 - 68 Aligned: 36 Modelled: 36 Confidence: 47.1% Identity: 8% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 1cjx chain A domain 2 Region: 12 - 72 Aligned: 24 Modelled: 24 Confidence: 38.2% Identity: 46% Fold: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family: Extradiol dioxygenases Phyre2 PDB 2ca9 chain B Region: 33 - 68 Aligned: 36 Modelled: 36 Confidence: 30.6% Identity: 17% PDB header:transcription Chain: B: PDB Molecule:putative nickel-responsive regulator; PDBTitle: apo-nikr from helicobacter pylori in closed trans-2 conformation Phyre2 PDB 1cjx chain C Region: 12 - 72 Aligned: 24 Modelled: 24 Confidence: 27.2% Identity: 46% PDB header:oxidoreductase Chain: C: PDB Molecule:4-hydroxyphenylpyruvate dioxygenase; PDBTitle: crystal structure of pseudomonas fluorescens hppd Phyre2 PDB 2izp chain B Region: 35 - 90 Aligned: 56 Modelled: 56 Confidence: 24.6% Identity: 30% PDB header:toxin Chain: B: PDB Molecule:putative membrane antigen; PDBTitle: bipd - an invasion prtein associated with the type-iii2 secretion system of burkholderia pseudomallei. Phyre2 PDB 3soh chain B Region: 38 - 92 Aligned: 55 Modelled: 55 Confidence: 23.9% Identity: 24% PDB header:motor protein Chain: B: PDB Molecule:flagellar motor switch protein flig; PDBTitle: architecture of the flagellar rotor Phyre2 PDB 2bj3 chain D Region: 33 - 67 Aligned: 35 Modelled: 35 Confidence: 22.8% Identity: 9% PDB header:transcription Chain: D: PDB Molecule:nickel responsive regulator; PDBTitle: nikr-apo Phyre2 PDB 2izp chain A domain 1 Region: 35 - 90 Aligned: 56 Modelled: 56 Confidence: 22.0% Identity: 30% Fold: IpaD-like Superfamily: IpaD-like Family: IpaD-like Phyre2 PDB 1q5v chain B Region: 33 - 68 Aligned: 36 Modelled: 36 Confidence: 20.0% Identity: 14% PDB header:transcription Chain: B: PDB Molecule:nickel responsive regulator; PDBTitle: apo-nikr Phyre2 PDB 4rgw chain B Region: 28 - 53 Aligned: 26 Modelled: 26 Confidence: 18.8% Identity: 31% PDB header:transferase/transcription Chain: B: PDB Molecule:transcription initiation factor tfiid subunit 7; PDBTitle: crystal structure of a taf1-taf7 complex in human transcription factor2 iid Phyre2 PDB 1v4a chain A domain 2 Region: 36 - 105 Aligned: 70 Modelled: 70 Confidence: 18.4% Identity: 20% Fold: Nucleotidyltransferase Superfamily: Nucleotidyltransferase Family: GlnE-like domain Phyre2 PDB 2hza chain B domain 1 Region: 33 - 65 Aligned: 33 Modelled: 33 Confidence: 16.8% Identity: 15% Fold: Ribbon-helix-helix Superfamily: Ribbon-helix-helix Family: CopG-like Phyre2 PDB 2k5j chain B Region: 33 - 72 Aligned: 39 Modelled: 40 Confidence: 13.1% Identity: 23% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 Phyre2 PDB 4me7 chain E Region: 31 - 77 Aligned: 46 Modelled: 44 Confidence: 11.5% Identity: 28% PDB header:hydrolase/hydrolase inhibitor Chain: E: PDB Molecule:antitoxin endoai; PDBTitle: crystal structure of bacillus subtilis toxin mazf in complex with2 cognate antitoxin maze Phyre2 PDB 3hqx chain A Region: 6 - 40 Aligned: 33 Modelled: 35 Confidence: 10.3% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0345 protein aciad0356; PDBTitle: crystal structure of protein of unknown function (duf1255,pf06865)2 from acinetobacter sp. adp1 Phyre2 PDB 3mky chain P Region: 35 - 80 Aligned: 43 Modelled: 43 Confidence: 10.3% Identity: 16% PDB header:dna binding protein/dna Chain: P: PDB Molecule:protein sopb; PDBTitle: structure of sopb(155-323)-18mer dna complex, i23 form Phyre2 PDB 2wl2 chain B Region: 8 - 45 Aligned: 29 Modelled: 38 Confidence: 10.1% Identity: 28% PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit a; PDBTitle: crystal structure of n-terminal domain of gyra with the2 antibiotic simocyclinone d8 Phyre2 1 c3kxeD_ 2 c5cegC_ 3 d2hzaa1 4 d2bj7a1 5 d1cjxa2 6 c2ca9B_ 7 c1cjxC_ 8 c2izpB_ 9 c3sohB_ 10 c2bj3D_ 11 d2izpa1 12 c1q5vB_ 13 c4rgwB_ 14 d1v4aa2 15 d2hzab1 16 c2k5jB_ 17 c4me7E_ 18 c3hqxA_ 19 c3mkyP_ 20 c2wl2B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36