1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	T	A	P	Y	G	V	R	L	L	V	G	A	A	T	V	A	V	E	E	T	M	K	L	P	R	T	I	L	M	Y	P	M	T	L	A	S	Q	A	A	H	V	V	M	R	F	Q	Q	G	L	A	E	L	V	I	K	G	D	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	L	E	T	L	F	P	P	K	D	E	K	P	E	W	A	T	F	D	E	D	L	P	D	A	L	E	G	T	S	I	P	L	L	G	L	S	D	A	S	E	A	K	N	D	D	R	R	S	D	G	R	F	A	L	Y	S	V	S	D
Secondary structure
SS confidence
Disorder								?																?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	P	E	T	T	T	A	S	R	S	A	D	R	S	T	N	P	K	T	A	K	H	P	K	S	A	A	K	P	T	V	P	T	P	A	V	A	A	E	L	D	Y	P	A	L	T	L	A	Q	L	R	A	R	L	H	T	L	D	V	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
Sequence		E	L	E	A	L	L	A	Y	E	Q	A	T	K	A	R	A	P	F	Q	T	L	L	A	N	R	I	T	R	A	T	A	K
Secondary structure
SS confidence
Disorder														?																		?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 40%) Alpha helix ( 51%) Beta strand ( 0%)

Rank Aligned region

PDB 1ov9 chain A Region: 165 - 187 Aligned: 23 Modelled: 23 Confidence: 57.4% Identity: 35% Fold: H-NS histone-like proteins Superfamily: H-NS histone-like proteins Family: H-NS histone-like proteins Phyre2 PDB 3cqb chain B Region: 174 - 192 Aligned: 19 Modelled: 19 Confidence: 56.8% Identity: 42% PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 Phyre2 PDB 3sl9 chain F Region: 163 - 186 Aligned: 24 Modelled: 24 Confidence: 33.6% Identity: 25% PDB header:signaling protein, protein binding Chain: F: PDB Molecule:b-cell cll/lymphoma 9 protein; PDBTitle: x-ray structure of beta catenin in complex with bcl9 Phyre2 PDB 3sl9 chain C Region: 163 - 186 Aligned: 24 Modelled: 24 Confidence: 33.5% Identity: 25% PDB header:signaling protein, protein binding Chain: C: PDB Molecule:b-cell cll/lymphoma 9 protein; PDBTitle: x-ray structure of beta catenin in complex with bcl9 Phyre2 PDB 1zar chain A domain 1 Region: 170 - 210 Aligned: 41 Modelled: 41 Confidence: 32.2% Identity: 7% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Rio2 serine protein kinase N-terminal domain Phyre2 PDB 1k1v chain A Region: 164 - 195 Aligned: 32 Modelled: 32 Confidence: 30.9% Identity: 22% Fold: A DNA-binding domain in eukaryotic transcription factors Superfamily: A DNA-binding domain in eukaryotic transcription factors Family: A DNA-binding domain in eukaryotic transcription factors Phyre2 PDB 5cws chain F Region: 164 - 177 Aligned: 14 Modelled: 14 Confidence: 29.4% Identity: 57% PDB header:protein transport Chain: F: PDB Molecule:nucleoporin nic96; PDBTitle: crystal structure of the intact chaetomium thermophilum nsp1-nup49-2 nup57 channel nucleoporin heterotrimer bound to its nic96 nuclear3 pore complex attachment site Phyre2 PDB 5cws chain L Region: 164 - 177 Aligned: 14 Modelled: 14 Confidence: 27.1% Identity: 57% PDB header:protein transport Chain: L: PDB Molecule:nucleoporin nic96; PDBTitle: crystal structure of the intact chaetomium thermophilum nsp1-nup49-2 nup57 channel nucleoporin heterotrimer bound to its nic96 nuclear3 pore complex attachment site Phyre2 PDB 1dl6 chain A Region: 70 - 82 Aligned: 13 Modelled: 13 Confidence: 24.6% Identity: 46% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 2n90 chain B Region: 5 - 18 Aligned: 14 Modelled: 14 Confidence: 24.5% Identity: 50% PDB header:transferase Chain: B: PDB Molecule:high affinity nerve growth factor receptor; PDBTitle: trka transmembrane domain nmr structure in dpc micelles Phyre2 PDB 2n90 chain A Region: 5 - 18 Aligned: 14 Modelled: 14 Confidence: 24.5% Identity: 50% PDB header:transferase Chain: A: PDB Molecule:high affinity nerve growth factor receptor; PDBTitle: trka transmembrane domain nmr structure in dpc micelles Phyre2 PDB 2jo8 chain B Region: 164 - 205 Aligned: 42 Modelled: 42 Confidence: 24.5% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: solution structure of c-terminal domain of human mammalian2 sterile 20-like kinase 1 (mst1) Phyre2 PDB 1q08 chain A Region: 170 - 212 Aligned: 43 Modelled: 43 Confidence: 23.8% Identity: 14% Fold: Putative DNA-binding domain Superfamily: Putative DNA-binding domain Family: DNA-binding N-terminal domain of transcription activators Phyre2 PDB 4il3 chain B Region: 174 - 202 Aligned: 29 Modelled: 29 Confidence: 23.6% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:ste24p; PDBTitle: crystal structure of s. mikatae ste24p Phyre2 PDB 2ga1 chain A domain 1 Region: 163 - 196 Aligned: 34 Modelled: 34 Confidence: 22.8% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: Homeodomain-like Family: Alr1493-like Phyre2 PDB 4l0n chain G Region: 164 - 205 Aligned: 42 Modelled: 42 Confidence: 20.8% Identity: 26% PDB header:transferase Chain: G: PDB Molecule:serine/threonine-protein kinase 3; PDBTitle: crystal structure of stk3 (mst2) sarah domain Phyre2 PDB 1h1j chain S Region: 161 - 176 Aligned: 16 Modelled: 16 Confidence: 17.8% Identity: 44% Fold: LEM/SAP HeH motif Superfamily: SAP domain Family: SAP domain Phyre2 PDB 1pft chain A Region: 70 - 79 Aligned: 10 Modelled: 10 Confidence: 14.8% Identity: 60% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 1dpu chain A Region: 163 - 188 Aligned: 26 Modelled: 26 Confidence: 14.7% Identity: 15% PDB header:dna binding protein Chain: A: PDB Molecule:replication protein a (rpa32) c-terminal domain; PDBTitle: solution structure of the c-terminal domain of human rpa322 complexed with ung2(73-88) Phyre2 PDB 1dpu chain A Region: 163 - 188 Aligned: 26 Modelled: 26 Confidence: 14.7% Identity: 15% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: C-terminal domain of RPA32 Phyre2 1 d1ov9a_ 2 c3cqbB_ 3 c3sl9F_ 4 c3sl9C_ 5 d1zara1 6 d1k1va_ 7 c5cwsF_ 8 c5cwsL_ 9 d1dl6a_ 10 c2n90B_ 11 c2n90A_ 12 c2jo8B_ 13 d1q08a_ 14 c4il3B_ 15 d2ga1a1 16 c4l0nG_ 17 d1h1js_ 18 d1pfta_ 19 c1dpuA_ 20 d1dpua_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48