1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	P	N	L	Q	L	V	Q	E	P	A	A	D	A	L	L	N	A	N	P	F	A	L	L	V	G	M	L	L	D	Q	Q	V	P	M	E	T	A	F	A	G	P	K	K	I	A	D	R	M	G	S	F	D	A	G	D	I	A	D	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																							?	?	?	?	?	?																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	P	D	K	F	V	A	L	C	S	E	R	P	A	I	H	R	F	P	G	S	M	A	K	R	I	Q	A	L	A	Q	I	I	V	D	R	Y	D	G	D	A	A	A	L	W	T	A	G	E	P	D	G	N	E	L	L	R	R	L	K
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	L	P	G	F	G	E	Q	K	A	R	I	F	L	A	L	L	G	K	Q	Y	G	V	T	P	K	G	W	Q	V	A	A	G	E	F	G	Q	P	G	T	Y	L	S	V	A	D	I	V	D	A	G	S	L	G	Q	V	R	S	H	K
Secondary structure
SS confidence
Disorder																														?		?	?		?	?	?	?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.
Sequence		R	Q	R	K	A	A	A	K	A	E	G	K	A	P	T
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 18%) Alpha helix ( 72%) Beta strand ( 0%)

Rank Aligned region

PDB 2yg8 chain B Region: 5 - 173 Aligned: 157 Modelled: 169 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:dna-3-methyladenine glycosidase ii, putative; PDBTitle: structure of an unusual 3-methyladenine dna glycosylase ii (alka) from2 deinococcus radiodurans Phyre2 PDB 1mpg chain B Region: 10 - 159 Aligned: 136 Modelled: 142 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: B: PDB Molecule:3-methyladenine dna glycosylase ii; PDBTitle: 3-methyladenine dna glycosylase ii from escherichia coli Phyre2 PDB 3s6i chain A Region: 6 - 181 Aligned: 156 Modelled: 165 Confidence: 100.0% Identity: 15% PDB header:hydrolase/dna Chain: A: PDB Molecule:dna-3-methyladenine glycosylase 1; PDBTitle: schizosaccaromyces pombe 3-methyladenine dna glycosylase (mag1) in2 complex with abasic-dna. Phyre2 PDB 4b24 chain A Region: 8 - 181 Aligned: 154 Modelled: 166 Confidence: 100.0% Identity: 10% PDB header:hydrolase/dna Chain: A: PDB Molecule:probable dna-3-methyladenine glycosylase 2; PDBTitle: unprecedented sculpting of dna at abasic sites by dna glycoslase2 homolog mag2 Phyre2 PDB 1mpg chain A domain 1 Region: 7 - 157 Aligned: 137 Modelled: 143 Confidence: 100.0% Identity: 22% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: DNA repair glycosylase, 2 C-terminal domains Phyre2 PDB 1kea chain A Region: 10 - 194 Aligned: 168 Modelled: 185 Confidence: 100.0% Identity: 14% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 PDB 4uob chain A Region: 8 - 149 Aligned: 138 Modelled: 142 Confidence: 100.0% Identity: 14% PDB header:lyase Chain: A: PDB Molecule:endonuclease iii-3; PDBTitle: crystal structure of deinococcus radiodurans endonuclease iii-3 Phyre2 PDB 1pu6 chain A Region: 3 - 149 Aligned: 135 Modelled: 147 Confidence: 100.0% Identity: 19% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: 3-Methyladenine DNA glycosylase III (MagIII) Phyre2 PDB 1orn chain A Region: 3 - 194 Aligned: 175 Modelled: 192 Confidence: 100.0% Identity: 17% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Endonuclease III Phyre2 PDB 2abk chain A Region: 3 - 194 Aligned: 174 Modelled: 192 Confidence: 100.0% Identity: 18% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Endonuclease III Phyre2 PDB 4unf chain A Region: 10 - 194 Aligned: 176 Modelled: 185 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:endonuclease iii-1; PDBTitle: crystal structure of deinococcus radiodurans endonuclease iii-1 Phyre2 PDB 1rrq chain A Region: 17 - 189 Aligned: 144 Modelled: 162 Confidence: 100.0% Identity: 19% PDB header:hydrolase/dna Chain: A: PDB Molecule:muty; PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair Phyre2 PDB 2noh chain A domain 1 Region: 19 - 184 Aligned: 156 Modelled: 158 Confidence: 100.0% Identity: 17% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: DNA repair glycosylase, 2 C-terminal domains Phyre2 PDB 3f10 chain A Region: 14 - 184 Aligned: 147 Modelled: 163 Confidence: 100.0% Identity: 20% PDB header:hydrolase, lyase Chain: A: PDB Molecule:8-oxoguanine-dna-glycosylase; PDBTitle: crystal structure of clostridium acetobutylicum 8-oxoguanine dna2 glycosylase in complex with 8-oxoguanosine Phyre2 PDB 1yqm chain A Region: 14 - 184 Aligned: 161 Modelled: 164 Confidence: 100.0% Identity: 17% PDB header:hydrolase/dna Chain: A: PDB Molecule:n-glycosylase/dna lyase; PDBTitle: catalytically inactive human 8-oxoguanine glycosylase2 crosslinked to 7-deazaguanine containing dna Phyre2 PDB 4ejy chain A Region: 14 - 149 Aligned: 123 Modelled: 128 Confidence: 100.0% Identity: 19% PDB header:hydrolase/dna Chain: A: PDB Molecule:3-methyladenine dna glycosylase; PDBTitle: structure of mbogg1 in complex with high affinity dna ligand Phyre2 PDB 1kg2 chain A Region: 8 - 189 Aligned: 153 Modelled: 172 Confidence: 100.0% Identity: 14% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 PDB 1ko9 chain A Region: 14 - 184 Aligned: 160 Modelled: 171 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:8-oxoguanine dna glycosylase; PDBTitle: native structure of the human 8-oxoguanine dna glycosylase2 hogg1 Phyre2 PDB 3n5n chain X Region: 16 - 189 Aligned: 146 Modelled: 174 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: X: PDB Molecule:a/g-specific adenine dna glycosylase; PDBTitle: crystal structure analysis of the catalytic domain and interdomain2 connector of human muty homologue Phyre2 PDB 1ngn chain A Region: 14 - 155 Aligned: 118 Modelled: 124 Confidence: 100.0% Identity: 14% Fold: DNA-glycosylase Superfamily: DNA-glycosylase Family: Mismatch glycosylase Phyre2 1 c2yg8B_ 2 c1mpgB_ 3 c3s6iA_ 4 c4b24A_ 5 d1mpga1 6 d1keaa_ 7 c4uobA_ 8 d1pu6a_ 9 d1orna_ 10 d2abka_ 11 c4unfA_ 12 c1rrqA_ 13 d2noha1 14 c3f10A_ 15 c1yqmA_ 16 c4ejyA_ 17 d1kg2a_ 18 c1ko9A_ 19 c3n5nX_ 20 d1ngna_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150