1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	V	M	A	Q	M	A	M	V	M	N	L	D	K	C	I	G	C	H	T	C	S	V	T	C	K	Q	A	W	T	N	R	S	G	T	E	Y	V	W	F	N	N	V	E	T	R	P	G	V	G	Y	P	R	T	Y	E	D	Q	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?																										?	?	?	?												?		?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	W	R	G	G	W	V	R	D	K	K	G	R	L	R	L	R	D	G	G	R	I	H	K	L	L	R	I	F	A	N	P	K	L	P	T	I	G	D	Y	Y	E	P	W	T	Y	D	Y	E	N	L	T	S	A	P	A	G	D	T	F
Secondary structure
SS confidence
Disorder									?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	T	A	A	P	R	S	L	I	S	G	N	P	M	K	V	S	W	G	S	N	W	D	D	N	L	A	G	S	P	E	I	V	P	N	D	P	V	L	K	K	V	N	Q	V	N	Q	E	V	K	L	K	L	E	E	T	F	M	F	Y
Secondary structure
SS confidence
Disorder																											?		?	?	?	?																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	P	R	I	C	E	H	C	L	N	P	S	C	V	A	S	C	P	S	G	A	M	Y	K	R	T	E	D	G	I	V	L	V	D	Q	D	R	C	R	G	W	R	M	C	V	S	G	C	P	Y	K	K	V	Y	F	N	H	K	T	G
Secondary structure
SS confidence
Disorder																																																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		K	A	E	K	C	T	L	C	Y	P	R	I	E	V	G	L	P	T	V	C	S	E	T	C	V	G	R	L	R	Y	L	G	L	V	L	Y	D	V	D	Q	V	L	Q	A	A	S	V	E	S	D	T	D	L	Y	E	A	Q	R	R	I
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	L	D	P	H	D	P	R	V	I	A	G	A	R	A	E	G	I	A	D	E	W	I	E	A	A	Q	R	S	P	V	Y	A	L	I	N	T	Y	R	V	A	L	P	L	H	P	E	Y	R	T	M	P	M	V	W	Y	I	P	P	L
Secondary structure
SS confidence
Disorder															?													?												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		S	P	V	V	D	A	V	S	R	D	G	H	D	G	E	D	L	G	N	L	F	G	A	L	D	A	L	R	I	P	I	A	Y	L	A	E	L	F	T	A	G	D	T	E	V	V	A	G	V	L	R	R	L	A	A	M	R	C	Y	M
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	D	I	N	L	G	R	E	T	Q	P	H	I	P	E	S	V	G	M	T	E	E	Q	I	Y	Q	M	Y	R	L	L	A	V	A	K	Y	E	E	R	Y	V	I	P	T	S	Y	A	G	E	L	P	A	A	A	M	T	D	D	M	G
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?						?	?	?	?																																				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		C	S	L	S	V	D	G	G	P	G	M	Y	E	S	G	P	F	G	Q	G	S	P	T	P	V	P	I	A	V	E	S	F	H	A	L	Q	H	A	G	S	A	A	T	G	G	A	G	R	S	R	V	N	L	L	N	W	D	P	N	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.
Sequence		A	A	A	G	L	F	P	E	P	Q	P	S	K	D	V	V	Q	R
Secondary structure
SS confidence
Disorder			?		?	?	?	?				?	?	?			?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 32%) Beta strand ( 12%)

Rank Aligned region

PDB 1y5i chain B domain 1 Region: 1 - 495 Aligned: 488 Modelled: 495 Confidence: 100.0% Identity: 53% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 2ivf chain B Region: 4 - 438 Aligned: 327 Modelled: 339 Confidence: 100.0% Identity: 41% PDB header:oxidoreductase Chain: B: PDB Molecule:ethylbenzene dehydrogenase beta-subunit; PDBTitle: ethylbenzene dehydrogenase from aromatoleum aromaticum Phyre2 PDB 4ydd chain F Region: 3 - 463 Aligned: 324 Modelled: 343 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: F: PDB Molecule:dmso reductase family type ii enzyme, iron-sulfur subunit; PDBTitle: crystal structure of the perchlorate reductase pcrab from azospira2 suillum ps Phyre2 PDB 6btm chain B Region: 6 - 360 Aligned: 218 Modelled: 232 Confidence: 100.0% Identity: 29% PDB header:membrane protein Chain: B: PDB Molecule:alternative complex iii subunit b; PDBTitle: structure of alternative complex iii from flavobacterium johnsoniae2 (wild type) Phyre2 PDB 6f0k chain B Region: 6 - 360 Aligned: 192 Modelled: 206 Confidence: 100.0% Identity: 35% PDB header:membrane protein Chain: B: PDB Molecule:fe-s-cluster-containing hydrogenase; PDBTitle: alternative complex iii Phyre2 PDB 1ti2 chain F Region: 4 - 357 Aligned: 185 Modelled: 189 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: F: PDB Molecule:pyrogallol hydroxytransferase small subunit; PDBTitle: crystal structure of pyrogallol-phloroglucinol transhydroxylase from2 pelobacter acidigallici Phyre2 PDB 6cza chain B Region: 6 - 361 Aligned: 180 Modelled: 182 Confidence: 100.0% Identity: 42% PDB header:oxidoreductase Chain: B: PDB Molecule:4fe-4s ferredoxin, iron-sulfur binding domain protein; PDBTitle: the arsenate respiratory reductase (arr) complex from shewanella sp.2 ana-3 bound to phosphate Phyre2 PDB 2vpy chain B Region: 4 - 361 Aligned: 182 Modelled: 184 Confidence: 100.0% Identity: 40% PDB header:oxidoreductase Chain: B: PDB Molecule:nrfc protein; PDBTitle: polysulfide reductase with bound quinone inhibitor,2 pentachlorophenol (pcp) Phyre2 PDB 1kqf chain B domain 1 Region: 2 - 361 Aligned: 207 Modelled: 219 Confidence: 100.0% Identity: 30% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 1vlf chain N domain 2 Region: 4 - 357 Aligned: 185 Modelled: 213 Confidence: 100.0% Identity: 31% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 1kqf chain B Region: 4 - 286 Aligned: 171 Modelled: 187 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: B: PDB Molecule:formate dehydrogenase, nitrate-inducible, iron-sulfur PDBTitle: formate dehydrogenase n from e. coli Phyre2 PDB 1h0h chain B Region: 7 - 364 Aligned: 200 Modelled: 212 Confidence: 100.0% Identity: 20% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 4z3z chain E Region: 8 - 328 Aligned: 158 Modelled: 174 Confidence: 99.8% Identity: 20% PDB header:oxidoreductase Chain: E: PDB Molecule:iron-sulfur cluster-binding oxidoreductase, putative PDBTitle: active site complex bambc of benzoyl coenzyme a reductase in complex2 with zinc Phyre2 PDB 5t5i chain N Region: 9 - 244 Aligned: 234 Modelled: 236 Confidence: 99.7% Identity: 13% PDB header:oxidoreductase Chain: N: PDB Molecule:tungsten formylmethanofuran dehydrogenase subunit fwdf; PDBTitle: tungsten-containing formylmethanofuran dehydrogenase from2 methanothermobacter wolfeii, orthorhombic form at 1.9 a Phyre2 PDB 1hfe chain L Region: 165 - 398 Aligned: 192 Modelled: 207 Confidence: 99.5% Identity: 13% PDB header:hydrogenase Chain: L: PDB Molecule:protein (fe-only hydrogenase (e.c.1.18.99.1) PDBTitle: 1.6 a resolution structure of the fe-only hydrogenase from2 desulfovibrio desulfuricans Phyre2 PDB 1gx7 chain A Region: 177 - 398 Aligned: 184 Modelled: 194 Confidence: 99.5% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:periplasmic [fe] hydrogenase large subunit; PDBTitle: best model of the electron transfer complex between cytochrome c3 and2 [fe]-hydrogenase Phyre2 PDB 1jnr chain B Region: 178 - 313 Aligned: 135 Modelled: 136 Confidence: 99.5% Identity: 18% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: Ferredoxin domains from multidomain proteins Phyre2 PDB 3gyx chain J Region: 178 - 289 Aligned: 111 Modelled: 112 Confidence: 99.4% Identity: 14% PDB header:oxidoreductase Chain: J: PDB Molecule:adenylylsulfate reductase; PDBTitle: crystal structure of adenylylsulfate reductase from2 desulfovibrio gigas Phyre2 PDB 7fd1 chain A Region: 179 - 238 Aligned: 58 Modelled: 60 Confidence: 99.3% Identity: 22% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: 7-Fe ferredoxin Phyre2 PDB 1h98 chain A Region: 178 - 256 Aligned: 77 Modelled: 79 Confidence: 99.3% Identity: 22% Fold: Ferredoxin-like Superfamily: 4Fe-4S ferredoxins Family: 7-Fe ferredoxin Phyre2 1 d1y5ib1 2 c2ivfB_ 3 c4yddF_ 4 c6btmB_ 5 c6f0kB_ 6 c1ti2F_ 7 c6czaB_ 8 c2vpyB_ 9 d1kqfb1 10 d1vlfn2 11 c1kqfB_ 12 d1h0hb_ 13 c4z3zE_ 14 c5t5iN_ 15 c1hfeL_ 16 c1gx7A_ 17 d1jnrb_ 18 c3gyxJ_ 19 d7fd1a_ 20 d1h98a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143