Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1183_(mmpL10)_1321526_1324534
DateWed Jul 31 22:05:27 BST 2019
Unique Job ID2daeb567671c229b
SequenceVVGCWVALAL ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:65.296 Y:86.972 Z:94.736
Model (left) based on template c6ajjA_
Top template information
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
Confidence and coverage
Confidence:100.0% Coverage: 68%
685 residues ( 68% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
948 residues ( 95%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6ajjA_
100.0 21
PDB header:membrane protein, hydrolase
Chain: A: PDB Molecule:drug exporters of the rnd superfamily-like protein,
PDBTitle: crystal structure of mycolic acid transporter mmpl3 from mycobacterium2 smegmatis complexed with ica38
2c5lq3F_
100.0 15
PDB header:transport protein
Chain: F: PDB Molecule:cmeb;
PDBTitle: structures and transport dynamics of the campylobacter jejuni2 multidrug efflux pump cmeb
3c6owsB_
100.0 15
PDB header:membrane protein
Chain: B: PDB Molecule:efflux pump membrane transporter;
PDBTitle: cryo-em structure of an acinetobacter baumannii multidrug efflux pump
4c3k07A_
100.0 13
PDB header:transport protein
Chain: A: PDB Molecule:cation efflux system protein cusa;
PDBTitle: crystal structure of cusa
5c4mt1A_
100.0 14
PDB header:membrane protein, tranport protein
Chain: A: PDB Molecule:drug efflux protein;
PDBTitle: crystal structure of the neisseria gonorrhoeae mtrd inner membrane2 multidrug efflux pump
6c2v50A_
100.0 14
PDB header:membrane protein
Chain: A: PDB Molecule:multidrug resistance protein mexb;
PDBTitle: the missing part of the bacterial mexab-oprm system: structural2 determination of the multidrug exporter mexb
7c1oy8A_
100.0 15
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
8c4k0eA_
100.0 12
PDB header:transport protein
Chain: A: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
9c6dmoA_
100.0 13
PDB header:protein binding
Chain: A: PDB Molecule:protein patched homolog 1;
PDBTitle: cryo-em structure of human ptch1 with three mutations2 l282q/t500f/p504l
10c5khnB_
100.0 18
PDB header:membrane protein
Chain: B: PDB Molecule:rnd transporter;
PDBTitle: crystal structures of the burkholderia multivorans hopanoid2 transporter hpnn
11c6csxA_
100.0 15
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb;
PDBTitle: single particles cryo-em structure of acrb d407a associated with lipid2 bilayer at 3.0 angstrom
12c4k0eC_
100.0 13
PDB header:transport protein
Chain: C: PDB Molecule:heavy metal cation tricomponent efflux pump znea(czca-
PDBTitle: x-ray crystal structure of a heavy metal efflux pump, crystal form ii
13c3jd8A_
100.0 11
PDB header:membrane protein
Chain: A: PDB Molecule:niemann-pick c1 protein;
PDBTitle: cryo-em structure of the full-length human npc1 at 4.4 angstrom
14c3aqpB_
100.0 16
PDB header:membrane protein
Chain: B: PDB Molecule:probable secdf protein-export membrane protein;
PDBTitle: crystal structure of secdf, a translocon-associated membrane protein,2 from thermus thrmophilus
15c5xamA_
100.0 18
PDB header:membrane protein
Chain: A: PDB Molecule:protein translocase subunit secd;
PDBTitle: crystal structure of secdf in i form at 4 a resolution
16c5mg3D_
100.0 18
PDB header:chaperone
Chain: D: PDB Molecule:protein translocase subunit secd;
PDBTitle: em fitted model of bacterial holo-translocon
17d1iwga8
100.0 17
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
18c5mg3F_
99.9 11
PDB header:chaperone
Chain: F: PDB Molecule:protein translocase subunit secf;
PDBTitle: em fitted model of bacterial holo-translocon
19d1iwga7
99.9 14
Fold:Multidrug efflux transporter AcrB transmembrane domain
Superfamily:Multidrug efflux transporter AcrB transmembrane domain
Family:Multidrug efflux transporter AcrB transmembrane domain
20c5ensA_
99.4 13
PDB header:transport protein
Chain: A: PDB Molecule:multidrug efflux pump subunit acrb,multidrug efflux pump
PDBTitle: rhodamine bound structure of bacterial efflux pump.
21c4r86B_
not modelled 98.8 8
PDB header:protein transport
Chain: B: PDB Molecule:rnd family aminoglycoside/multidrug efflux pump;
PDBTitle: crystal structure of aminoglycoside/multidrug efflux system acrd from2 salmonella typhimurium
22d1iwga6
not modelled 91.2 15
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
23d1iwga4
not modelled 83.5 10
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
24c6o7xa_
not modelled 82.3 9
PDB header:membrane protein
Chain: A: PDB Molecule:vacuolar atp synthase catalytic subunit a;
PDBTitle: saccharomyces cerevisiae v-atpase stv1-v1vo state 3
25c6o7ua_
not modelled 81.9 10
PDB header:membrane protein
Chain: A: PDB Molecule:
PDBTitle: saccharomyces cerevisiae v-atpase stv1-vo
26d1iwga2
not modelled 74.8 11
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
27c2yvxD_
not modelled 49.1 8
PDB header:transport protein
Chain: D: PDB Molecule:mg2+ transporter mgte;
PDBTitle: crystal structure of magnesium transporter mgte
28d1iwga3
not modelled 42.3 15
Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
29d2nwwa1
not modelled 42.0 9
Fold:Proton glutamate symport protein
Superfamily:Proton glutamate symport protein
Family:Proton glutamate symport protein
30c4av3A_
not modelled 41.7 17
PDB header:hydrolase
Chain: A: PDB Molecule:k(+)-stimulated pyrophosphate-energized sodium pump;
PDBTitle: crystal structure of thermotoga maritima sodium pumping membrane2 integral pyrophosphatase with metal ions in active site
31c1ciiA_
not modelled 37.5 25
PDB header:transmembrane protein
Chain: A: PDB Molecule:colicin ia;
PDBTitle: colicin ia
32c5gasN_
not modelled 33.0 11
PDB header:hydrolase
Chain: N: PDB Molecule:archaeal/vacuolar-type h+-atpase subunit i;
PDBTitle: thermus thermophilus v/a-atpase, conformation 2
33c5a96A_
not modelled 29.0 40
PDB header:viral protein
Chain: A: PDB Molecule:polyhedrin;
PDBTitle: crystal structure of lymantria dispar cpv14 polyhedra
34c5zlgA_
not modelled 28.0 9
PDB header:oxidoreductase
Chain: A: PDB Molecule:cytochrome b reductase 1;
PDBTitle: human duodenal cytochrome b (dcytb) in zinc ion and ascorbate bound2 form
35c3jcuz_
not modelled 14.8 15
PDB header:membrane protein
Chain: Z: PDB Molecule:photosystem ii reaction center protein z;
PDBTitle: cryo-em structure of spinach psii-lhcii supercomplex at 3.2 angstrom2 resolution
36c2mk9A_
not modelled 14.3 4
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
37c2mkaB_
not modelled 14.3 4
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
38c2mkaC_
not modelled 14.3 4
PDB header:immune system
Chain: C: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
39c2mk9B_
not modelled 14.3 4
PDB header:immune system
Chain: B: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the dimeric transmembrane domain of toll-like2 receptor 3
40c2mkaA_
not modelled 14.3 4
PDB header:immune system
Chain: A: PDB Molecule:toll-like receptor 3;
PDBTitle: spatial structure of the toll-like receptor 3 transmembrane domain in2 the trimeric state
41d1a87a_
not modelled 12.2 20
Fold:Toxins' membrane translocation domains
Superfamily:Colicin
Family:Colicin
42c1a87A_
not modelled 12.2 20
PDB header:bacteriocin
Chain: A: PDB Molecule:colicin n;
PDBTitle: colicin n
43c2kncB_
not modelled 11.6 12
PDB header:cell adhesion
Chain: B: PDB Molecule:integrin beta-3;
PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex
44d1iwga5
not modelled 11.5 16
Fold:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Superfamily:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Family:Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
45d2d81a1
not modelled 11.4 22
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PHB depolymerase-like
46c3j20P_
not modelled 11.4 13
PDB header:ribosome
Chain: P: PDB Molecule:30s ribosomal protein s14p type z;
PDBTitle: promiscuous behavior of proteins in archaeal ribosomes revealed by2 cryo-em: implications for evolution of eukaryotic ribosomes (30s3 ribosomal subunit)
47c6n52B_
not modelled 9.4 15
PDB header:membrane protein
Chain: B: PDB Molecule:metabotropic glutamate receptor 5;
PDBTitle: metabotropic glutamate receptor 5 apo form
48d1kf6d_
not modelled 9.3 8
Fold:Heme-binding four-helical bundle
Superfamily:Fumarate reductase respiratory complex transmembrane subunits
Family:Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD)
49c4cdiC_
not modelled 8.9 10
PDB header:membrane protein
Chain: C: PDB Molecule:predicted protein;
PDBTitle: crystal structure of acrb-acrz complex
50c3wo6A_
not modelled 8.8 18
PDB header:membrane protein
Chain: A: PDB Molecule:membrane protein insertase yidc 2;
PDBTitle: crystal structure of yidc from bacillus halodurans (form i)
51c6b2zf_
not modelled 8.7 10
PDB header:membrane protein
Chain: F: PDB Molecule:atp synthase subunit c, mitochondrial;
PDBTitle: cryo-em structure of the dimeric fo region of yeast mitochondrial atp2 synthase
52c6eznH_
not modelled 8.6 8
PDB header:membrane protein
Chain: H: PDB Molecule:dolichyl-diphosphooligosaccharide--protein
PDBTitle: cryo-em structure of the yeast oligosaccharyltransferase (ost) complex
53c6b8ht_
not modelled 8.5 10
PDB header:membrane protein
Chain: T: PDB Molecule:atp synthase subunit 9, mitochondrial;
PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer
54c2qg8A_
not modelled 8.2 22
PDB header:transferase
Chain: A: PDB Molecule:acyl carrier protein synthase py06285;
PDBTitle: plasmodium yoelii acyl carrier protein synthase py06285 with adp bound
55d1jb0i_
not modelled 8.1 6
Fold:Single transmembrane helix
Superfamily:Subunit VIII of photosystem I reaction centre, PsaI
Family:Subunit VIII of photosystem I reaction centre, PsaI
56c4fe1I_
not modelled 8.1 6
PDB header:photosynthesis
Chain: I: PDB Molecule:photosystem i reaction center subunit viii;
PDBTitle: improving the accuracy of macromolecular structure refinement at 7 a2 resolution
57c4gn0D_
not modelled 8.0 9
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
58c2ww9B_
not modelled 8.0 7
PDB header:ribosome
Chain: B: PDB Molecule:protein transport protein sss1;
PDBTitle: cryo-em structure of the active yeast ssh1 complex bound to the yeast2 80s ribosome
59c4rfsS_
not modelled 7.8 16
PDB header:hydrolase, transport protein
Chain: S: PDB Molecule:substrate binding pritein s;
PDBTitle: structure of a pantothenate energy coupling factor transporter
60c2bbjB_
not modelled 7.8 6
PDB header:metal transport/membrane protein
Chain: B: PDB Molecule:divalent cation transport-related protein;
PDBTitle: crystal structure of the cora mg2+ transporter
61c5n9yB_
not modelled 7.7 11
PDB header:membrane protein
Chain: B: PDB Molecule:zinc transport protein zntb;
PDBTitle: the full-length structure of zntb
62c2k1lB_
not modelled 7.4 21
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
63c2k1kA_
not modelled 7.4 21
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
64c2k1lA_
not modelled 7.4 21
PDB header:signaling protein
Chain: A: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 6.3
65c2k1kB_
not modelled 7.4 21
PDB header:signaling protein
Chain: B: PDB Molecule:ephrin type-a receptor 1;
PDBTitle: nmr structures of dimeric transmembrane domain of the2 receptor tyrosine kinase epha1 in lipid bicelles at ph 4.3
66c6ahrB_
not modelled 7.4 19
PDB header:hydrolase/rna
Chain: B: PDB Molecule:ribonucleases p/mrp protein subunit pop1;
PDBTitle: cryo-em structure of human ribonuclease p
67c3v7oA_
not modelled 7.3 21
PDB header:transcription
Chain: A: PDB Molecule:minor nucleoprotein vp30;
PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30 (strain2 reston-89)
68c3wvfA_
not modelled 7.3 23
PDB header:chaperone
Chain: A: PDB Molecule:membrane protein insertase yidc;
PDBTitle: crystal structure of yidc from escherichia coli
69c2bvtB_
not modelled 6.6 30
PDB header:hydrolase
Chain: B: PDB Molecule:beta-1,4-mannanase;
PDBTitle: the structure of a modular endo-beta-1,4-mannanase from cellulomonas2 fimi explains the product specificity of glycoside hydrolase family3 26 mannanases.
70c2kseA_
not modelled 6.5 37
PDB header:transferase
Chain: A: PDB Molecule:sensor protein qsec;
PDBTitle: backbone structure of the membrane domain of e. coli histidine kinase2 receptor qsec, center for structures of membrane proteins (csmp)3 target 4311c
71c6dkuA_
not modelled 6.5 7
PDB header:unknown function
Chain: A: PDB Molecule:vp35;
PDBTitle: crystal structure of myotis vp35 mutant of interferon inhibitory2 domain
72c3tijA_
not modelled 6.3 10
PDB header:membrane protein
Chain: A: PDB Molecule:nupc family protein;
PDBTitle: crystal structure of a concentrative nucleoside transporter from2 vibrio cholerae
73c3eamB_
not modelled 6.2 12
PDB header:membrane protein, transport protein
Chain: B: PDB Molecule:glr4197 protein;
PDBTitle: an open-pore structure of a bacterial pentameric ligand-2 gated ion channel
74d2axtz1
not modelled 6.1 27
Fold:Transmembrane helix hairpin
Superfamily:PsbZ-like
Family:PsbZ-like
75d2yvxa3
not modelled 6.0 7
Fold:MgtE membrane domain-like
Superfamily:MgtE membrane domain-like
Family:MgtE membrane domain-like
76c5ir6B_
not modelled 6.0 11
PDB header:oxidoreductase
Chain: B: PDB Molecule:bd-type quinol oxidase subunit ii;
PDBTitle: the structure of bd oxidase from geobacillus thermodenitrificans
77c3zm8A_
not modelled 5.9 33
PDB header:hydrolase
Chain: A: PDB Molecule:gh26 endo-beta-1,4-mannanase;
PDBTitle: crystal structure of podospora anserina gh26-cbm352 beta-(1,4)-mannanase
78c4xtrG_
not modelled 5.8 19
PDB header:hydrolase/transport protein
Chain: G: PDB Molecule:pep12p;
PDBTitle: structure of get3 bound to the transmembrane domain of pep12
79d2cwqa1
not modelled 5.7 6
Fold:AhpD-like
Superfamily:AhpD-like
Family:TTHA0727-like
80c5cmoB_
not modelled 5.6 28
PDB header:transferase
Chain: B: PDB Molecule:holo-[acyl-carrier-protein] synthase;
PDBTitle: crystal structure of holo-[acyl-carrier-protein] synthase (acps) from2 neisseria meningitidis
81c2i8bB_
not modelled 5.5 19
PDB header:viral protein
Chain: B: PDB Molecule:minor nucleoprotein vp30;
PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30
82d1sd4a_
not modelled 5.5 11
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Penicillinase repressor
83c6mctK_
not modelled 5.5 24
PDB header:de novo protein
Chain: K: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
84c6mctI_
not modelled 5.5 24
PDB header:de novo protein
Chain: I: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
85c6mq2D_
not modelled 5.5 24
PDB header:de novo protein
Chain: D: PDB Molecule:mini-evgl membrane protein;
PDBTitle: de novo design of membrane protein--mini-evgl membrane protein, c22212 form-2
86c6mctA_
not modelled 5.5 24
PDB header:de novo protein
Chain: A: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
87c6mctE_
not modelled 5.5 24
PDB header:de novo protein
Chain: E: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
88c6mctO_
not modelled 5.5 24
PDB header:de novo protein
Chain: O: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
89c6mpwA_
not modelled 5.5 24
PDB header:de novo protein
Chain: A: PDB Molecule:mini-evgl membrane protein;
PDBTitle: de novo design of membrane protein--mini-evgl membrane protein, c22212 form-1
90c6mctG_
not modelled 5.5 24
PDB header:de novo protein
Chain: G: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
91c6mctD_
not modelled 5.5 24
PDB header:de novo protein
Chain: D: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
92c6mctN_
not modelled 5.5 24
PDB header:de novo protein
Chain: N: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
93c6mctJ_
not modelled 5.5 24
PDB header:de novo protein
Chain: J: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
94c6mctC_
not modelled 5.5 24
PDB header:de novo protein
Chain: C: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
95c6mctB_
not modelled 5.5 24
PDB header:de novo protein
Chain: B: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
96c6mctM_
not modelled 5.5 24
PDB header:de novo protein
Chain: M: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
97c6mctH_
not modelled 5.5 24
PDB header:de novo protein
Chain: H: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
98c6mctL_
not modelled 5.5 24
PDB header:de novo protein
Chain: L: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction
99c6mctF_
not modelled 5.5 24
PDB header:de novo protein
Chain: F: PDB Molecule:mini-evgl membrane protein;
PDBTitle: a designed pentameric membrane protein stabilized by van der waals2 interaction

Binding site prediction 

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Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below