1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	R	V	I	A	G	A	F	A	V	W	L	V	G	W	A	G	G	F	G	T	A	I	A	A	S	E	P	A	Y	P	W	A	P	G	P	P	P	S	P	S	P	V	G	D	A	S	T	A	K	V	V	Y	A	L	G	G	A	R
Secondary structure
SS confidence
Disorder		?	?	?			?	?		?																	?	?	?	?	?	?	?	?	?	?	?			?		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	P	G	I	P	W	Y	E	Y	T	N	Q	A	G	S	Q	Y	F	P	N	A	K	H	D	L	I	D	Y	P	A	G	A	A	F	S	W	W	P	T	M	L	L	P	P	G	S	H	Q	D	N	M	T	V	G	V	A	V	K	D	G
Secondary structure
SS confidence
Disorder																																											?		?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	N	S	L	D	N	A	I	H	H	G	T	D	P	A	A	A	V	G	L	S	Q	G	S	L	V	L	D	Q	E	Q	A	R	L	A	N	D	P	T	A	P	A	P	D	K	L	Q	F	T	T	F	G	D	P	T	G	R	H	A	F
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?	?														?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	A	S	F	L	A	R	I	F	P	P	G	S	H	I	P	I	P	F	I	E	Y	T	M	P	Q	Q	V	D	S	Q	Y	D	T	N	H	V	V	T	A	Y	D	G	F	S	D	F	P	D	R	P	D	N	L	L	A	V	A	N	A
Secondary structure
SS confidence
Disorder		?																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	I	G	A	A	I	A	H	T	P	I	G	F	T	G	P	G	D	V	P	P	Q	N	I	R	T	T	V	N	S	R	G	A	T	T	T	T	Y	L	V	P	V	N	H	L	P	L	T	L	P	L	R	Y	L	G	M	S	D	A	E
Secondary structure
SS confidence
Disorder																	?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
Sequence		V	D	Q	I	D	S	V	L	Q	P	Q	I	D	A	A	Y	A	R	N	D	N	W	F	T	R	P	V	S	V	D	P	V	R	G	L	D	P	L	T	A	P	G	S	I	V	E	G	A	R	G	L	L	G	S	P	A	F	G	G
Secondary structure
SS confidence
Disorder																				?		?	?		?			?		?	?	?						?	?	?	?	?										?		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 20%) Alpha helix ( 30%) Beta strand ( 11%)

Rank Aligned region

PDB 3aja chain A Region: 86 - 252 Aligned: 158 Modelled: 167 Confidence: 99.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of msmeg_6394 Phyre2 PDB 2czq chain B Region: 45 - 251 Aligned: 173 Modelled: 186 Confidence: 99.4% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:cutinase-like protein; PDBTitle: a novel cutinase-like protein from cryptococcus sp. Phyre2 PDB 1qoz chain A Region: 47 - 251 Aligned: 173 Modelled: 180 Confidence: 99.4% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 1g66 chain A Region: 48 - 251 Aligned: 168 Modelled: 179 Confidence: 99.4% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3hc7 chain A Region: 52 - 229 Aligned: 158 Modelled: 178 Confidence: 99.3% Identity: 19% PDB header:cell adhesion Chain: A: PDB Molecule:gene 12 protein; PDBTitle: crystal structure of lysin b from mycobacteriophage d29 Phyre2 PDB 1cex chain A Region: 36 - 251 Aligned: 161 Modelled: 165 Confidence: 99.1% Identity: 19% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Cutinase-like Phyre2 PDB 3gbs chain A Region: 46 - 251 Aligned: 153 Modelled: 170 Confidence: 99.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:cutinase 1; PDBTitle: crystal structure of aspergillus oryzae cutinase Phyre2 PDB 3dd5 chain F Region: 36 - 251 Aligned: 165 Modelled: 180 Confidence: 99.0% Identity: 12% PDB header:hydrolase Chain: F: PDB Molecule:cutinase; PDBTitle: glomerella cingulata e600-cutinase complex Phyre2 PDB 5x88 chain A Region: 86 - 226 Aligned: 99 Modelled: 103 Confidence: 98.8% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:cutinase; PDBTitle: a crystal structure of cutinases from malbranchea cinnamomea Phyre2 PDB 4oyl chain C Region: 36 - 226 Aligned: 150 Modelled: 164 Confidence: 98.7% Identity: 15% PDB header:hydrolase Chain: C: PDB Molecule:cutinase; PDBTitle: humicola insolens cutinase in complex with mono-ethylphosphate Phyre2 PDB 4psd chain A Region: 1 - 226 Aligned: 168 Modelled: 172 Confidence: 98.5% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate esterase family 5; PDBTitle: structure of trichoderma reesei cutinase native form. Phyre2 PDB 5xav chain B Region: 104 - 174 Aligned: 68 Modelled: 71 Confidence: 95.3% Identity: 13% PDB header:biosynthetic protein Chain: B: PDB Molecule:intracellular polyhydroxyalkanoate synthase; PDBTitle: structure of phac from chromobacterium sp. usm2 Phyre2 PDB 3icv chain A Region: 89 - 225 Aligned: 124 Modelled: 137 Confidence: 94.9% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:lipase b; PDBTitle: structural consequences of a circular permutation on lipase b from2 candida antartica Phyre2 PDB 1tca chain A Region: 101 - 176 Aligned: 72 Modelled: 76 Confidence: 94.4% Identity: 11% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Fungal lipases Phyre2 PDB 5t6o chain A Region: 104 - 174 Aligned: 68 Modelled: 71 Confidence: 94.3% Identity: 18% PDB header:biosynthetic protein Chain: A: PDB Molecule:poly-beta-hydroxybuterate polymerase; PDBTitle: structure of the catalytic domain of the class i polyhydroxybutyrate2 synthase from cupriavidus necator Phyre2 PDB 3lp5 chain A Region: 108 - 176 Aligned: 67 Modelled: 69 Confidence: 93.2% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative cell surface hydrolase; PDBTitle: the crystal structure of the putative cell surface hydrolase from2 lactobacillus plantarum wcfs1 Phyre2 PDB 3ds8 chain A Region: 116 - 176 Aligned: 59 Modelled: 61 Confidence: 93.1% Identity: 31% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin2722 protein; PDBTitle: the crysatl structure of the gene lin2722 products from listeria2 innocua Phyre2 PDB 2ppl chain A Region: 113 - 204 Aligned: 85 Modelled: 92 Confidence: 91.5% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:pancreatic lipase-related protein 1; PDBTitle: human pancreatic lipase-related protein 1 Phyre2 PDB 1rp1 chain A domain 2 Region: 113 - 204 Aligned: 85 Modelled: 92 Confidence: 91.2% Identity: 22% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Pancreatic lipase, N-terminal domain Phyre2 PDB 4qnn chain C Region: 113 - 177 Aligned: 61 Modelled: 61 Confidence: 91.2% Identity: 18% PDB header:hydrolase Chain: C: PDB Molecule:phospholipase a 1 from hornet(vespa basalis) venom; PDBTitle: crystal structure of phospholipase a 1 from hornet(vespa basalis)2 venom Phyre2 1 c3ajaA_ 2 c2czqB_ 3 d1qoza_ 4 d1g66a_ 5 c3hc7A_ 6 d1cexa_ 7 c3gbsA_ 8 c3dd5F_ 9 c5x88A_ 10 c4oylC_ 11 c4psdA_ 12 c5xavB_ 13 c3icvA_ 14 d1tcaa_ 15 c5t6oA_ 16 c3lp5A_ 17 c3ds8A_ 18 c2pplA_ 19 d1rp1a2 20 c4qnnC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111