1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	R	V	A	L	A	C	L	V	G	S	A	I	E	F	Y	D	F	L	I	Y	G	T	A	A	A	L	V	F	P	T	V	F	F	P	H	L	D	P	T	V	A	A	V	A	S	M	G	T	F	A	V	A	F	L	S	R	P	F
Secondary structure
SS confidence
Disorder		?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	A	A	V	F	G	Y	F	G	D	R	L	G	R	K	K	T	L	V	A	T	L	L	I	M	G	L	A	T	V	T	V	G	L	V	P	T	T	V	A	I	G	A	A	A	P	L	I	L	T	T	M	R	L	L	Q	G	F	A	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	G	E	W	A	G	S	A	L	L	S	A	E	Y	A	P	A	S	K	R	G	W	Y	G	M	F	T	V	V	G	G	G	I	A	L	V	L	T	S	L	T	F	L	G	V	N	Y	T	I	G	E	S	S	P	T	F	M	Q	W	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		W	R	I	P	F	L	V	S	A	A	L	I	A	V	A	L	Y	V	R	F	N	I	D	E	T	P	V	F	A	R	E	R	A	D	E	K	T	R	L	G	P	A	E	T	P	I	A	Q	V	L	R	R	Q	R	R	E	I	V	L	A
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	G	S	A	V	C	C	F	G	F	V	Y	L	A	S	T	Y	L	A	S	Y	A	Q	T	R	L	G	Y	S	R	G	S	I	L	F	D	S	V	L	G	G	L	L	C	I	V	F	T	A	L	S	S	A	L	C	D	Q	L	G	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	R	V	L	L	A	G	W	A	V	A	L	P	W	S	L	L	V	M	P	L	I	D	S	G	S	P	S	L	F	A	V	A	V	V	G	M	Y	A	I	G	G	F	G	F	G	P	T	A	S	F	I	P	E	L	F	A	T	S	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		R	Y	T	G	S	A	L	A	A	N	L	A	G	V	A	G	G	A	L	P	P	V	I	A	G	A	L	V	A	T	Y	G	S	W	A	I	G	V	M	L	A	I	L	A	L	I	S	L	V	C	T	Y	R	L	P	E	T	A	G	S
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.
Sequence		A	L	V	S	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 5%) Alpha helix ( 80%) Beta strand ( 0%) TM helix ( 64%) (View membrane topology prediction)

Rank Aligned region

PDB 6h7d chain A Region: 3 - 424 Aligned: 413 Modelled: 422 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: A: PDB Molecule:sugar transport protein 10; PDBTitle: crystal structure of a. thaliana sugar transport protein 10 in complex2 with glucose in the outward occluded state Phyre2 PDB 5c65 chain A Region: 4 - 424 Aligned: 415 Modelled: 421 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 2, facilitated glucose transporter PDBTitle: structure of the human glucose transporter glut3 / slc2a3 Phyre2 PDB 4j05 chain A Region: 2 - 425 Aligned: 412 Modelled: 424 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:phosphate transporter; PDBTitle: crystal structure of a eukaryotic phosphate transporter Phyre2 PDB 4ybq chain B Region: 4 - 424 Aligned: 410 Modelled: 416 Confidence: 100.0% Identity: 16% PDB header:transport protein/immune system Chain: B: PDB Molecule:solute carrier family 2, facilitated glucose transporter PDBTitle: rat glut5 with fv in the outward-open form Phyre2 PDB 4gbz chain A Region: 3 - 424 Aligned: 421 Modelled: 422 Confidence: 100.0% Identity: 17% PDB header:transport protein Chain: A: PDB Molecule:d-xylose-proton symporter; PDBTitle: the structure of the mfs (major facilitator superfamily) proton:xylose2 symporter xyle bound to d-glucose Phyre2 PDB 4lds chain B Region: 4 - 419 Aligned: 400 Modelled: 416 Confidence: 100.0% Identity: 17% PDB header:transport protein, membrane protein Chain: B: PDB Molecule:bicyclomycin resistance protein tcab; PDBTitle: the inward-facing structure of the glucose transporter from2 staphylococcus epidermidis Phyre2 PDB 4pyp chain A Region: 1 - 417 Aligned: 411 Modelled: 417 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:solute carrier family 2, facilitated glucose transporter PDBTitle: crystal structure of the human glucose transporter glut1 Phyre2 PDB 1pw4 chain A Region: 3 - 420 Aligned: 397 Modelled: 418 Confidence: 100.0% Identity: 13% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: Glycerol-3-phosphate transporter Phyre2 PDB 6e9o chain A Region: 3 - 419 Aligned: 385 Modelled: 417 Confidence: 100.0% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:d-galactonate transport; PDBTitle: e. coli d-galactonate:proton symporter mutant e133q in the outward2 substrate-bound form Phyre2 PDB 3wdo chain A Region: 2 - 421 Aligned: 384 Modelled: 405 Confidence: 100.0% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:mfs transporter; PDBTitle: structure of e. coli yajr transporter Phyre2 PDB 3o7p chain A Region: 3 - 417 Aligned: 396 Modelled: 415 Confidence: 100.0% Identity: 10% PDB header:transport protein Chain: A: PDB Molecule:l-fucose-proton symporter; PDBTitle: crystal structure of the e.coli fucose:proton symporter, fucp (n162a) Phyre2 PDB 1pv7 chain A Region: 2 - 420 Aligned: 399 Modelled: 412 Confidence: 100.0% Identity: 9% Fold: MFS general substrate transporter Superfamily: MFS general substrate transporter Family: LacY-like proton/sugar symporter Phyre2 PDB 6g9x chain B Region: 3 - 420 Aligned: 366 Modelled: 386 Confidence: 100.0% Identity: 15% PDB header:membrane protein Chain: B: PDB Molecule:major facilitator superfamily mfs_1; PDBTitle: crystal structure of a mfs transporter at 2.54 angstroem resolution Phyre2 PDB 4iky chain A Region: 2 - 419 Aligned: 408 Modelled: 418 Confidence: 100.0% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:di-tripeptide abc transporter (permease); PDBTitle: crystal structure of peptide transporter pot (e310q mutant) in complex2 with sulfate Phyre2 PDB 1pv7 chain B Region: 2 - 420 Aligned: 399 Modelled: 412 Confidence: 100.0% Identity: 9% PDB header:transport protein Chain: B: PDB Molecule:lactose permease; PDBTitle: crystal structure of lactose permease with tdg Phyre2 PDB 4zp0 chain A Region: 4 - 414 Aligned: 380 Modelled: 396 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:multidrug transporter mdfa; PDBTitle: crystal structure of e. coli multidrug transporter mdfa in complex2 with deoxycholate Phyre2 PDB 4cl5 chain B Region: 3 - 422 Aligned: 410 Modelled: 420 Confidence: 100.0% Identity: 13% PDB header:transport protein Chain: B: PDB Molecule:nitrate transporter 1.1; PDBTitle: crystal structure of the nitrate transporter nrt1.1 from2 arabidopsis thaliana in complex with nitrate. Phyre2 PDB 6exs chain A Region: 3 - 419 Aligned: 407 Modelled: 417 Confidence: 100.0% Identity: 9% PDB header:membrane protein Chain: A: PDB Molecule:peptide abc transporter permease; PDBTitle: crystal structure of a pot family transporter in complex with2 thioalcohol conjugated peptide. Phyre2 PDB 2gfp chain A Region: 4 - 408 Aligned: 370 Modelled: 387 Confidence: 100.0% Identity: 13% PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein d; PDBTitle: structure of the multidrug transporter emrd from2 escherichia coli Phyre2 PDB 6gs7 chain A Region: 3 - 419 Aligned: 402 Modelled: 417 Confidence: 100.0% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:dipeptide and tripeptide permease a; PDBTitle: crystal structure of peptide transporter dtpa-nanobody in glycine2 buffer Phyre2 1 c6h7dA_ 2 c5c65A_ 3 c4j05A_ 4 c4ybqB_ 5 c4gbzA_ 6 c4ldsB_ 7 c4pypA_ 8 d1pw4a_ 9 c6e9oA_ 10 c3wdoA_ 11 c3o7pA_ 12 d1pv7a_ 13 c6g9xB_ 14 c4ikyA_ 15 c1pv7B_ 16 c4zp0A_ 17 c4cl5B_ 18 c6exsA_ 19 c2gfpA_ 20 c6gs7A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37