1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	T	V	T	G	A	A	G	I	G	L	A	T	L	A	A	D	G	S	V	L	D	T	W	F	P	A	P	E	L	T	E	S	G	T	S	A	T	S	R	L	A	V	S	D	V	P	V	E	L	A	A	L	I	G	R	D	D	D
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																												?	?	?	?	?	?	?	?		?	?	?	?	?									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	R	T	E	T	I	A	V	R	T	V	I	G	S	L	D	D	V	A	A	D	P	Y	D	A	Y	L	R	L	H	L	L	S	H	R	L	V	A	P	H	G	L	N	A	G	G	L	F	G	V	L	T	N	V	V	W	T	N	H	G
Secondary structure
SS confidence
Disorder		?	?	?	?													?	?	?															?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	C	A	I	D	G	F	E	A	V	R	A	R	L	R	R	R	G	P	V	T	V	Y	G	V	D	K	F	P	R	M	V	D	Y	V	V	P	T	G	V	R	I	A	D	A	D	R	V	R	L	G	A	H	L	A	P	G	T	T	V
Secondary structure
SS confidence
Disorder															?		?																	?				?	?				?			?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		M	H	E	G	F	V	N	Y	N	A	G	T	L	G	A	S	M	V	E	G	R	I	S	A	G	V	V	V	G	D	G	S	D	V	G	G	G	A	S	I	M	G	T	L	S	G	G	G	T	H	V	I	S	I	G	K	R	C	L	L
Secondary structure
SS confidence
Disorder																	?	?				?	?	?	?					?	?				?					?			?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	A	N	S	G	L	G	I	S	L	G	D	D	C	V	V	E	A	G	L	Y	V	T	A	G	T	R	V	T	M	P	D	S	N	S	V	K	A	R	E	L	S	G	S	S	N	L	L	F	R	R	N	S	V	S	G	A	V	E	V
Secondary structure
SS confidence
Disorder																																		?	?		?		?	?					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Sequence		L	A	R	D	G	Q	G	I	A	L	N	E	D	L	H	A	N
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?			?	?			?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 26%) Alpha helix ( 18%) Beta strand ( 44%)

Rank Aligned region

PDB 3fsy chain C Region: 4 - 303 Aligned: 297 Modelled: 300 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: C: PDB Molecule:tetrahydrodipicolinate n-succinyltransferase; PDBTitle: structure of tetrahydrodipicolinate n-succinyltransferase2 (rv1201c;dapd) in complex with succinyl-coa from mycobacterium3 tuberculosis Phyre2 PDB 2rij chain A Region: 5 - 309 Aligned: 298 Modelled: 300 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: A: PDB Molecule:putative 2,3,4,5-tetrahydropyridine-2-carboxylate n- PDBTitle: crystal structure of a putative 2,3,4,5-tetrahydropyridine-2-2 carboxylate n-succinyltransferase (cj1605c, dapd) from campylobacter3 jejuni at 1.90 a resolution Phyre2 PDB 3r5d chain A Region: 7 - 301 Aligned: 289 Modelled: 295 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: A: PDB Molecule:tetrahydrodipicolinate n-succinyletransferase; PDBTitle: pseudomonas aeruginosa dapd (pa3666) apoprotein Phyre2 PDB 5e3p chain A Region: 5 - 302 Aligned: 282 Modelled: 284 Confidence: 100.0% Identity: 68% PDB header:transferase Chain: A: PDB Molecule:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- PDBTitle: crystal strcuture of dapd from corynebacterium glutamicum Phyre2 PDB 3eg4 chain A Region: 124 - 268 Aligned: 144 Modelled: 145 Confidence: 99.9% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- PDBTitle: crystal structure of 2,3,4,5-tetrahydropyridine-2-2 carboxylate n-succinyltransferase from brucella melitensis3 biovar abortus 2308 Phyre2 PDB 3tdt chain A Region: 141 - 295 Aligned: 154 Modelled: 155 Confidence: 99.9% Identity: 25% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Tetrahydrodipicolinate-N-succinlytransferase, THDP-succinlytransferase, DapD Phyre2 PDB 6ckt chain A Region: 107 - 312 Aligned: 185 Modelled: 186 Confidence: 99.9% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- PDBTitle: crystal structure of 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n-2 succinyltransferase from legionella pneumophila philadelphia 1 Phyre2 PDB 1t3d chain A Region: 166 - 295 Aligned: 113 Modelled: 121 Confidence: 99.9% Identity: 18% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Serine acetyltransferase Phyre2 PDB 1t3d chain B Region: 166 - 295 Aligned: 113 Modelled: 129 Confidence: 99.9% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of serine acetyltransferase from e.coli at 2.2a Phyre2 PDB 1ssq chain A Region: 166 - 289 Aligned: 107 Modelled: 124 Confidence: 99.9% Identity: 18% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Serine acetyltransferase Phyre2 PDB 4n6b chain B Region: 166 - 289 Aligned: 103 Modelled: 124 Confidence: 99.8% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:serine acetyltransferase apoenzyme; PDBTitle: soybean serine acetyltransferase complexed with coa Phyre2 PDB 3mc4 chain A Region: 166 - 293 Aligned: 105 Modelled: 128 Confidence: 99.8% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:ww/rsp5/wwp domain:bacterial transferase hexapeptide PDBTitle: crystal structure of ww/rsp5/wwp domain: bacterial transferase2 hexapeptide repeat: serine o-acetyltransferase from brucella3 melitensis Phyre2 PDB 3q1x chain A Region: 162 - 267 Aligned: 98 Modelled: 106 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: crystal structure of entamoeba histolytica serine acetyltransferase 12 in complex with l-serine Phyre2 PDB 3cj8 chain B Region: 156 - 291 Aligned: 127 Modelled: 136 Confidence: 99.8% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- PDBTitle: crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n-2 succinyltransferase from enterococcus faecalis v583 Phyre2 PDB 3f1x chain A Region: 162 - 267 Aligned: 93 Modelled: 106 Confidence: 99.8% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:serine acetyltransferase; PDBTitle: three dimensional structure of the serine acetyltransferase from2 bacteroides vulgatus, northeast structural genomics consortium target3 bvr62. Phyre2 PDB 1krr chain A Region: 103 - 295 Aligned: 173 Modelled: 184 Confidence: 99.8% Identity: 15% Fold: Single-stranded left-handed beta-helix Superfamily: Trimeric LpxA-like enzymes Family: Galactoside acetyltransferase-like Phyre2 PDB 4mzu chain G Region: 156 - 290 Aligned: 118 Modelled: 135 Confidence: 99.8% Identity: 18% PDB header:isomerase, transferase Chain: G: PDB Molecule:wxcm-like protein; PDBTitle: crystal structure of fdtd, a bifunctional ketoisomerase/n-2 acetyltransferase from shewanella denitrificans Phyre2 PDB 2ic7 chain A Region: 119 - 291 Aligned: 156 Modelled: 173 Confidence: 99.8% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:maltose transacetylase; PDBTitle: crystal structure of maltose transacetylase from geobacillus2 kaustophilus Phyre2 PDB 2iu9 chain C Region: 153 - 291 Aligned: 130 Modelled: 139 Confidence: 99.8% Identity: 24% PDB header:transferase Chain: C: PDB Molecule:udp-3-o-[3-hydroxymyristoyl] glucosamine PDBTitle: chlamydia trachomatis lpxd with 100mm udpglcnac (complex ii) Phyre2 PDB 3i3a chain C Region: 160 - 316 Aligned: 143 Modelled: 157 Confidence: 99.8% Identity: 20% PDB header:transferase Chain: C: PDB Molecule:acyl-[acyl-carrier-protein]--udp-n- PDBTitle: structural basis for the sugar nucleotide and acyl chain2 selectivity of leptospira interrogans lpxa Phyre2 1 c3fsyC_ 2 c2rijA_ 3 c3r5dA_ 4 c5e3pA_ 5 c3eg4A_ 6 d3tdta_ 7 c6cktA_ 8 d1t3da_ 9 c1t3dB_ 10 d1ssqa_ 11 c4n6bB_ 12 c3mc4A_ 13 c3q1xA_ 14 c3cj8B_ 15 c3f1xA_ 16 d1krra_ 17 c4mzuG_ 18 c2ic7A_ 19 c2iu9C_ 20 c3i3aC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99