1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	V	V	P	L	G	E	V	R	N	R	L	S	E	Y	V	A	E	V	E	L	T	H	E	R	I	T	I	T	R	H	G	H	P	A	A	V	L	I	S	A	D	D	L	A	S	I	E	E	T	L	E	V	L	R	T	P	G	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.
Sequence		S	E	A	I	R	E	G	L	A	D	V	A	A	G	R	F	V	S	N	D	E	I	R	N	R	Y	T	A	R
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?									?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 16%) Alpha helix ( 63%) Beta strand ( 12%)

Rank Aligned region

PDB 3g5o chain A Region: 1 - 89 Aligned: 89 Modelled: 89 Confidence: 99.9% Identity: 43% PDB header:toxin/antitoxin Chain: A: PDB Molecule:uncharacterized protein rv2865; PDBTitle: the crystal structure of the toxin-antitoxin complex relbe2 (rv2865-2 2866) from mycobacterium tuberculosis Phyre2 PDB 3oei chain B Region: 3 - 86 Aligned: 83 Modelled: 84 Confidence: 99.9% Identity: 34% PDB header:toxin, protein binding Chain: B: PDB Molecule:relj (antitoxin rv3357); PDBTitle: crystal structure of mycobacterium tuberculosis reljk (rv3357-rv3358-2 relbe3) Phyre2 PDB 2a6q chain A domain 1 Region: 1 - 80 Aligned: 80 Modelled: 80 Confidence: 99.9% Identity: 29% Fold: YefM-like Superfamily: YefM-like Family: YefM-like Phyre2 PDB 3d55 chain A Region: 3 - 70 Aligned: 67 Modelled: 68 Confidence: 99.8% Identity: 33% PDB header:toxin inhibitor Chain: A: PDB Molecule:uncharacterized protein rv3357/mt3465; PDBTitle: crystal structure of m. tuberculosis yefm antitoxin Phyre2 PDB 2a6q chain B domain 1 Region: 1 - 55 Aligned: 55 Modelled: 55 Confidence: 99.7% Identity: 35% Fold: YefM-like Superfamily: YefM-like Family: YefM-like Phyre2 PDB 3hs2 chain H Region: 1 - 53 Aligned: 52 Modelled: 53 Confidence: 99.6% Identity: 29% PDB header:antitoxin Chain: H: PDB Molecule:prevent host death protein; PDBTitle: crystal structure of phd truncated to residue 57 in an orthorhombic2 space group Phyre2 PDB 3hry chain A Region: 1 - 50 Aligned: 49 Modelled: 50 Confidence: 99.5% Identity: 31% PDB header:antitoxin Chain: A: PDB Molecule:prevent host death protein; PDBTitle: crystal structure of phd in a trigonal space group and partially2 disordered Phyre2 PDB 2odk chain D Region: 1 - 51 Aligned: 50 Modelled: 50 Confidence: 99.4% Identity: 22% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein; PDBTitle: putative prevent-host-death protein from nitrosomonas europaea Phyre2 PDB 2odk chain A domain 1 Region: 1 - 51 Aligned: 50 Modelled: 50 Confidence: 99.3% Identity: 22% Fold: YefM-like Superfamily: YefM-like Family: YefM-like Phyre2 PDB 3k6q chain B Region: 1 - 48 Aligned: 46 Modelled: 47 Confidence: 94.6% Identity: 15% PDB header:ligand binding protein Chain: B: PDB Molecule:putative ligand binding protein; PDBTitle: crystal structure of an antitoxin part of a putative toxin/antitoxin2 system (swol_0700) from syntrophomonas wolfei subsp. wolfei at 1.80 a3 resolution Phyre2 PDB 3bpq chain A Region: 40 - 83 Aligned: 36 Modelled: 44 Confidence: 44.6% Identity: 28% PDB header:toxin Chain: A: PDB Molecule:antitoxin relb3; PDBTitle: crystal structure of relb-rele antitoxin-toxin complex from2 methanococcus jannaschii Phyre2 PDB 1ez4 chain A domain 2 Region: 26 - 73 Aligned: 45 Modelled: 48 Confidence: 34.4% Identity: 13% Fold: LDH C-terminal domain-like Superfamily: LDH C-terminal domain-like Family: Lactate & malate dehydrogenases, C-terminal domain Phyre2 PDB 5ceg chain C Region: 49 - 89 Aligned: 40 Modelled: 41 Confidence: 33.2% Identity: 18% PDB header:toxin Chain: C: PDB Molecule:addiction module antidote protein, copg/arc/metj family; PDBTitle: x-ray structure of toxin/anti-toxin complex from mesorhizobium2 opportunistum Phyre2 PDB 2qzs chain A Region: 24 - 88 Aligned: 64 Modelled: 65 Confidence: 30.0% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:glycogen synthase; PDBTitle: crystal structure of wild-type e.coli gs in complex with adp and2 glucose(wtgsb) Phyre2 PDB 3bpq chain C Region: 40 - 83 Aligned: 36 Modelled: 44 Confidence: 24.9% Identity: 28% PDB header:toxin Chain: C: PDB Molecule:antitoxin relb3; PDBTitle: crystal structure of relb-rele antitoxin-toxin complex from2 methanococcus jannaschii Phyre2 PDB 3oka chain A Region: 24 - 88 Aligned: 64 Modelled: 65 Confidence: 23.8% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:gdp-mannose-dependent alpha-(1-6)-phosphatidylinositol PDBTitle: crystal structure of corynebacterium glutamicum pimb' in complex with2 gdp-man (triclinic crystal form) Phyre2 PDB 1grj chain A domain 1 Region: 38 - 69 Aligned: 32 Modelled: 32 Confidence: 22.3% Identity: 22% Fold: Long alpha-hairpin Superfamily: GreA transcript cleavage protein, N-terminal domain Family: GreA transcript cleavage protein, N-terminal domain Phyre2 PDB 6nkl chain D Region: 23 - 56 Aligned: 34 Modelled: 34 Confidence: 22.2% Identity: 15% PDB header:antitoxin Chain: D: PDB Molecule:antitoxin vapb1; PDBTitle: 2.2 a resolution structure of vapbc-1 from nontypeable haemophilus2 influenzae Phyre2 PDB 4och chain A Region: 4 - 39 Aligned: 36 Modelled: 36 Confidence: 21.6% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:endonuclease muts2; PDBTitle: apo structure of smr domain of muts2 from deinococcus radiodurans Phyre2 PDB 1n0f chain F Region: 7 - 53 Aligned: 37 Modelled: 47 Confidence: 21.0% Identity: 16% PDB header:biosynthetic protein Chain: F: PDB Molecule:protein mraz; PDBTitle: crystal structure of a cell division and cell wall2 biosynthesis protein upf0040 from mycoplasma pneumoniae:3 indication of a novel fold with a possible new conserved4 sequence motif Phyre2 1 c3g5oA_ 2 c3oeiB_ 3 d2a6qa1 4 c3d55A_ 5 d2a6qb1 6 c3hs2H_ 7 c3hryA_ 8 c2odkD_ 9 d2odka1 10 c3k6qB_ 11 c3bpqA_ 12 d1ez4a2 13 c5cegC_ 14 c2qzsA_ 15 c3bpqC_ 16 c3okaA_ 17 d1grja1 18 c6nklD_ 19 c4ochA_ 20 c1n0fF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99