Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1249c_(-)_1393200_1393988
DateWed Jul 31 22:05:34 BST 2019
Unique Job ID441798dafb7b76b3
SequenceMSARRIRSWK ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:26.403 Y:25.112 Z:19.178
Model (left) based on template c6bv7A_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:sodium/calcium exchanger 1;
PDBTitle: nmr structure of sodium/calcium exchanger 1 (ncx1) two-helix bundle2 (thb) domain
Confidence and coverage
Confidence: 86.9% Coverage: 13%
33 residues ( 13% of your sequence) have been modelled with 86.9% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in JSmol
For other options to view your downloaded structure offline see the FAQ

Sequence analysis 

Download FASTA version

Secondary structure and disorder prediction [Show] 

Domain analysis [Show] 

Detailed template information [Hide] 

 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6bv7A_
86.9 15
PDB header:membrane protein
Chain: A: PDB Molecule:sodium/calcium exchanger 1;
PDBTitle: nmr structure of sodium/calcium exchanger 1 (ncx1) two-helix bundle2 (thb) domain
2d1kxpd3
84.7 27
Fold:Serum albumin-like
Superfamily:Serum albumin-like
Family:Serum albumin-like
3c2pmwB_
83.3 16
PDB header:hydrolase
Chain: B: PDB Molecule:proprotein convertase subtilisin/kexin type 9;
PDBTitle: the crystal structure of proprotein convertase subtilisin2 kexin type 9 (pcsk9)
4c1s2nB_
82.0 20
PDB header:hydrolase
Chain: B: PDB Molecule:extracellular subtilisin-like serine proteinase;
PDBTitle: crystal structure of a cold adapted subtilisin-like serine proteinase
5c4dztA_
79.2 20
PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:aqualysin-1;
PDBTitle: aqualysin i: the crystal structure of a serine protease from an2 extreme thermophile, thermus aquaticus yt-1
6c5yl7A_
78.2 25
PDB header:hydrolase
Chain: A: PDB Molecule:pseudoalteromonas arctica pamc 21717;
PDBTitle: proteases from pseudoalteromonas arctica pamc 21717 (pro21717)
7c3f7oB_
75.9 10
PDB header:hydrolase
Chain: B: PDB Molecule:serine protease;
PDBTitle: crystal structure of cuticle-degrading protease from paecilomyces2 lilacinus (pl646)
8c2b6nA_
75.8 27
PDB header:hydrolase
Chain: A: PDB Molecule:proteinase k;
PDBTitle: the 1.8 a crystal structure of a proteinase k like enzyme from a2 psychrotroph serratia species
9c2w2qA_
75.6 15
PDB header:hydrolase/receptor
Chain: A: PDB Molecule:proprotein convertase subtilisin/kexin type 9;
PDBTitle: pcsk9-deltac d374h mutant bound to wt egf-a of ldlr
10c5vlpA_
75.2 15
PDB header:hydrolase
Chain: A: PDB Molecule:proprotein convertase subtilisin/kexin type 9;
PDBTitle: pcsk9 complex with ldlr antagonist peptide and fab7g7
11c4j94A_
73.3 16
PDB header:hydrolase
Chain: A: PDB Molecule:membrane-anchored mycosin mycp1;
PDBTitle: crystal structure of mycp1 from the esx-1 type vii secretion system
12c4tr2A_
72.3 22
PDB header:hydrolase
Chain: A: PDB Molecule:subtilisin-like 1 serine protease;
PDBTitle: crystal structure of pvsub1
13c3bpsA_
71.2 15
PDB header:hydrolase/lipid transport
Chain: A: PDB Molecule:proprotein convertase subtilisin/kexin type 9;
PDBTitle: pcsk9:egf-a complex
14d1gnsa_
70.6 19
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
15c5vllA_
70.4 15
PDB header:hydrolase
Chain: A: PDB Molecule:proprotein convertase subtilisin/kexin type 9;
PDBTitle: short pcsk9 delta-p' complex with peptide pep3
16c3vv3B_
70.0 13
PDB header:hydrolase
Chain: B: PDB Molecule:deseasin mcp-01;
PDBTitle: crystal structure of deseasin mcp-01 from pseudoalteromonas sp. sm9913
17d2ixta1
69.7 18
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
18d1gcia_
69.6 21
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
19c5z6oA_
69.1 9
PDB header:hydrolase
Chain: A: PDB Molecule:protease;
PDBTitle: crystal structure of penicillium cyclopium protease
20d1to2e_
68.9 21
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
21c6paxA_
not modelled 68.7 18
PDB header:gene regulation/dna
Chain: A: PDB Molecule:homeobox protein pax-6;
PDBTitle: crystal structure of the human pax-6 paired domain-dna2 complex reveals a general model for pax protein-dna3 interactions
22c2k27A_
not modelled 67.9 15
PDB header:transcription regulator
Chain: A: PDB Molecule:paired box protein pax-8;
PDBTitle: solution structure of human pax8 paired box domain
23c4mzdA_
not modelled 67.6 13
PDB header:hydrolase
Chain: A: PDB Molecule:nisin leader peptide-processing serine protease nisp;
PDBTitle: high resolution crystal structure of the nisin leader peptidase nisp2 from lactococcus lactis
24d1k78a2
not modelled 67.1 18
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Paired domain
25c4kg7A_
not modelled 65.9 16
PDB header:hydrolase
Chain: A: PDB Molecule:peptidase s8 and s53, subtilisin, kexin, sedolisin;
PDBTitle: structure of mycp3 protease from the type vii (esx-3) secretion2 system.
26c3vtaB_
not modelled 63.2 23
PDB header:hydrolase
Chain: B: PDB Molecule:cucumisin;
PDBTitle: crystal structure of cucumisin, a subtilisin-like endoprotease from2 cucumis melo l
27c3hyiA_
not modelled 59.9 27
PDB header:transcription regulator
Chain: A: PDB Molecule:protein duf199/whia;
PDBTitle: crystal structure of full-length duf199/whia from thermatoga maritima
28d1bh6a_
not modelled 59.8 17
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
29c2iy9A_
not modelled 58.9 12
PDB header:toxin
Chain: A: PDB Molecule:suba;
PDBTitle: crystal structure of the a-subunit of the ab5 toxin from e.2 coli
30d6paxa2
not modelled 58.5 18
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Paired domain
31d1pdnc_
not modelled 57.5 28
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Paired domain
32d2ibaa1
not modelled 55.9 12
Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:Urate oxidase (uricase)
33d1r0re_
not modelled 55.7 21
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
34c4lvnA_
not modelled 54.6 19
PDB header:hydrolase/inhibitor/immune system
Chain: A: PDB Molecule:subtilisin-like serine protease;
PDBTitle: crystal structure of pfsub1-prodomain-nimp.m7 fab complex
35d2fbqa2
not modelled 50.7 19
Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
36c2oxaA_
not modelled 50.5 22
PDB header:hydrolase
Chain: A: PDB Molecule:extracellular serine protease;
PDBTitle: crystal structure of serine protease of aeromonas sobria
37c4r99B_
not modelled 49.9 15
PDB header:hydrolase
Chain: B: PDB Molecule:uricase;
PDBTitle: crystal structure of a uricase from bacillus fastidious
38d1j2ga1
not modelled 48.4 10
Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:Urate oxidase (uricase)
39c3zxyA_
not modelled 48.0 17
PDB header:hydrolase
Chain: A: PDB Molecule:subtilisin-like protein;
PDBTitle: structure of s218a mutant of the protease domain of pata
40c1p8jB_
not modelled 47.9 12
PDB header:hydrolase/hydrolase inhibitor
Chain: B: PDB Molecule:furin precursor;
PDBTitle: crystal structure of the proprotein convertase furin
41d1v6ca_
not modelled 45.6 19
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
42d1meea_
not modelled 45.4 24
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
43d1p8ja2
not modelled 44.4 13
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
44c6a4mA_
not modelled 42.6 12
PDB header:hydrolase
Chain: A: PDB Molecule:uric acid degradation bifunctional protein pucl;
PDBTitle: structure of urate oxidase from bacillus subtilis 168
45c5m98H_
not modelled 41.2 18
PDB header:oxidoreductase
Chain: H: PDB Molecule:uricase;
PDBTitle: crystal structure of urate oxidase from zebrafish
46c3whiA_
not modelled 41.0 22
PDB header:hydrolase
Chain: A: PDB Molecule:subtilisin e;
PDBTitle: crystal structure of unautoprocessed form of is1-inserted pro-2 subtilisin e
47d2id4a2
not modelled 40.1 17
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
48c1j2gC_
not modelled 39.9 10
PDB header:oxidoreductase
Chain: C: PDB Molecule:uricase;
PDBTitle: crystal structure of urate oxidase from bacillus sp. tb-90 co-2 crystallized with 8-azaxanthine
49d1wjta_
not modelled 39.0 15
Fold:N-cbl like
Superfamily:Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
Family:Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
50c1r56H_
not modelled 37.7 12
PDB header:oxidoreductase
Chain: H: PDB Molecule:uricase;
PDBTitle: uncomplexed urate oxidase from aspergillus flavus
51c3zxxA_
not modelled 36.6 17
PDB header:hydrolase
Chain: A: PDB Molecule:subtilisin-like protein;
PDBTitle: structure of self-cleaved protease domain of pata
52d1r6va_
not modelled 35.7 31
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
53c1r64A_
not modelled 34.9 15
PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:kexin;
PDBTitle: the 2.2 a crystal structure of kex2 protease in complex with ac-arg-2 glu-lys-boroarg peptidyl boronic acid inhibitor
54c2bf9A_
not modelled 34.3 24
PDB header:hormone
Chain: A: PDB Molecule:pancreatic hormone;
PDBTitle: anisotropic refinement of avian (turkey) pancreatic polypeptide at 0.2 99 angstroms resolution.
55c2x8jB_
not modelled 31.9 21
PDB header:hydrolase
Chain: B: PDB Molecule:intracellular subtilisin protease;
PDBTitle: intracellular subtilisin precursor from b. clausii
56c4aksA_
not modelled 30.6 6
PDB header:hydrolase
Chain: A: PDB Molecule:thiazoline oxidase/subtilisin-like protease;
PDBTitle: patg macrocyclase domain
57c2dezA_
not modelled 30.0 29
PDB header:neuropeptide
Chain: A: PDB Molecule:peptide yy;
PDBTitle: structure of human pyy
58d1eo0a_
not modelled 28.9 11
Fold:N-cbl like
Superfamily:Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
Family:Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
59c1tz5A_
not modelled 28.8 19
PDB header:hormone/growth factor
Chain: A: PDB Molecule:chimera of pancreatic hormone and neuropeptide y;
PDBTitle: [pnpy19-23]-hpp bound to dpc micelles
60c3i74B_
not modelled 26.9 31
PDB header:hydrolase/hydrolase inhibitor
Chain: B: PDB Molecule:subtilisin-like protease;
PDBTitle: crystal structure of the plant subtilisin-like protease sbt3 in2 complex with a chloromethylketone inhibitor
61c1ronA_
not modelled 26.9 10
PDB header:neuropeptide
Chain: A: PDB Molecule:neuropeptide y;
PDBTitle: nmr solution structure of human neuropeptide y
62c4wwxB_
not modelled 25.7 19
PDB header:hydrolase, ligase
Chain: B: PDB Molecule:v(d)j recombination-activating protein 1;
PDBTitle: crystal structure of the core rag1/2 recombinase
63c2ph0A_
not modelled 24.6 20
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the q6d2t7_erwct protein from erwinia carotovora.2 nesg target ewr41.
64c4wxmD_
not modelled 24.1 45
PDB header:transcription regulator
Chain: D: PDB Molecule:transcriptional regulator fleq;
PDBTitle: fleq rec domain from pseudomonas aeruginosa pao1
65c4r0gA_
not modelled 22.9 21
PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of lpg0393 from legionella pneumophila
66d1fdja_
not modelled 22.2 22
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
67c4h6wB_
not modelled 18.6 14
PDB header:hydrolase
Chain: B: PDB Molecule:n-terminal cyanobactin protease;
PDBTitle: structure of prenylagaramide maturation protease paga
68c6d79A_
not modelled 16.4 15
PDB header:transport protein
Chain: A: PDB Molecule:sulfate transporter cysz;
PDBTitle: structure of cysz, a sulfate permease from pseudomonas fragi
69c3pxpA_
not modelled 16.1 21
PDB header:transcription regulator
Chain: A: PDB Molecule:helix-turn-helix domain protein;
PDBTitle: crystal structure of a pas and dna binding domain containing protein2 (caur_2278) from chloroflexus aurantiacus j-10-fl at 2.30 a3 resolution
70c3wisA_
not modelled 15.5 24
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydromethanopterin reductase (afpa);
PDBTitle: crystal structure of burkholderia xenovorans dmrb in complex with fmn:2 a cubic protein cage for redox transfer
71d1fbaa_
not modelled 15.0 24
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
72c2oviA_
not modelled 14.4 5
PDB header:ligand binding protein, metal transport
Chain: A: PDB Molecule:hypothetical protein chux;
PDBTitle: structure of the heme binding protein chux
73c3mmtC_
not modelled 14.4 29
PDB header:hydrolase
Chain: C: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: crystal structure of fructose bisphosphate aldolase from bartonella2 henselae, bound to fructose bisphosphate
74c2pc4B_
not modelled 14.1 16
PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: crystal structure of fructose-bisphosphate aldolase from plasmodium2 falciparum in complex with trap-tail determined at 2.4 angstrom3 resolution
75d1qo5b_
not modelled 13.9 24
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
76c3lpcA_
not modelled 13.6 22
PDB header:hydrolase
Chain: A: PDB Molecule:aprb2;
PDBTitle: crystal structure of a subtilisin-like protease
77c2z2yC_
not modelled 13.5 6
PDB header:hydrolase
Chain: C: PDB Molecule:tk-subtilisin;
PDBTitle: crystal structure of autoprocessed form of tk-subtilisin
78c5ldwf_
not modelled 13.1 19
PDB header:oxidoreductase
Chain: F: PDB Molecule:nadh dehydrogenase [ubiquinone] flavoprotein 1,
PDBTitle: structure of mammalian respiratory complex i, class1
79c5lc5f_
not modelled 13.1 19
PDB header:oxidoreductase
Chain: F: PDB Molecule:nadh dehydrogenase [ubiquinone] flavoprotein 1,
PDBTitle: structure of mammalian respiratory complex i, class2
80c5exvD_
not modelled 12.7 35
PDB header:heme-binding protein
Chain: D: PDB Molecule:hemin-degrading hems.chux domain protein;
PDBTitle: crystal structure of heme binding protein hutx from vibrio cholerae
81c4y0lA_
not modelled 12.6 25
PDB header:membrane protein
Chain: A: PDB Molecule:putative membrane protein mmpl11;
PDBTitle: mycobacterial membrane protein mmpl11d2
82d2pwaa1
not modelled 12.0 9
Fold:Subtilisin-like
Superfamily:Subtilisin-like
Family:Subtilases
83d1zaia1
not modelled 11.7 20
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
84d2np3a2
not modelled 11.7 22
Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
85d1vi7a1
not modelled 11.4 47
Fold:Ribosomal protein S5 domain 2-like
Superfamily:Ribosomal protein S5 domain 2-like
Family:YigZ N-terminal domain-like
86c5m48A_
not modelled 11.4 16
PDB header:transcription
Chain: A: PDB Molecule:regulator of ty1 transposition protein 103;
PDBTitle: coiled coil domain of rtt103p
87c3onqB_
not modelled 11.1 16
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:regulator of polyketide synthase expression;
PDBTitle: crystal structure of regulator of polyketide synthase expression2 bad_0249 from bifidobacterium adolescentis
88d1n5ua2
not modelled 11.1 17
Fold:Serum albumin-like
Superfamily:Serum albumin-like
Family:Serum albumin-like
89d2bxpa1
not modelled 11.0 17
Fold:Serum albumin-like
Superfamily:Serum albumin-like
Family:Serum albumin-like
90c2qs0A_
not modelled 10.8 16
PDB header:biosynthetic protein
Chain: A: PDB Molecule:quinolinate synthetase a;
PDBTitle: quinolinate synthase from pyrococcus furiosus
91c1vi7A_
not modelled 10.5 44
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein yigz;
PDBTitle: crystal structure of an hypothetical protein
92c1fcuA_
not modelled 10.1 23
PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronoglucosaminidase;
PDBTitle: crystal structure (trigonal) of bee venom hyaluronidase
93c2pe4A_
not modelled 10.1 19
PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronidase-1;
PDBTitle: structure of human hyaluronidase 1, a hyaluronan hydrolyzing enzyme2 involved in tumor growth and angiogenesis
94c3qfhE_
not modelled 10.0 18
PDB header:hydrolase
Chain: E: PDB Molecule:epidermin leader peptide processing serine protease epip;
PDBTitle: 2.05 angstrom resolution crystal structure of epidermin leader peptide2 processing serine protease (epip) from staphylococcus aureus.
95c6f9mA_
not modelled 9.7 21
PDB header:hydrolase
Chain: A: PDB Molecule:serine protease;
PDBTitle: the lipy/f-motif in an intracellular subtilisin protease is involved2 in inhibition
96c3n0uB_
not modelled 9.5 18
PDB header:hydrolase, lyase
Chain: B: PDB Molecule:probable n-glycosylase/dna lyase;
PDBTitle: crystal structure of tm1821, the 8-oxoguanine dna glycosylase of2 thermotoga maritima
97d1fcqa_
not modelled 9.5 23
Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Bee venom hyaluronidase
98c6mwqB_
not modelled 9.4 20
PDB header:lyase/fluorescent protein
Chain: B: PDB Molecule:darpin, muscle-type aldolase chimeric fusion;
PDBTitle: single particle cryoem structure of a darpin-aldolase platform in2 complex with gfp
99c2kvcA_
not modelled 9.4 30
PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: solution structure of the mycobacterium tuberculosis protein rv0543c,2 a member of the duf3349 superfamily. seattle structural genomics3 center for infectious disease target mytud.17112.a

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below