Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1264_(-)_1411900_1413093
DateWed Jul 31 22:05:35 BST 2019
Unique Job IDd1f2d28de7a30be8
SequenceVTDHVREADD ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:60.739 Y:77.369 Z:62.141
Model (left) based on template c1y10C_
Top template information
PDB header:lyase
Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state
Confidence and coverage
Confidence:100.0% Coverage: 91%
363 residues ( 91% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

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#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1y10C_



100.0 100
PDB header:lyase
Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state
2c6fhtB_



100.0 18
PDB header:lyase
Chain: B: PDB Molecule:bacteriophytochrome,adenylate cyclase;
PDBTitle: crystal structure of an artificial phytochrome regulated2 adenylate/guanylate cyclase in its dark adapted pr form
3c2ev2B_



100.0 100
PDB header:lyase
Chain: B: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: structure of rv1264n, the regulatory domain of the mycobacterial2 adenylyl cylcase rv1264, at ph 8.5
4c4yusA_



100.0 19
PDB header:lyase
Chain: A: PDB Molecule:family 3 adenylate cyclase;
PDBTitle: crystal structure of photoactivated adenylyl cyclase of a2 cyanobacteriaoscillatoria acuminata in hexagonal form
5d1fx2a_



100.0 22
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
6d1fx4a_



100.0 23
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
7c5nbyA_



100.0 19
PDB header:lyase
Chain: A: PDB Molecule:beta subunit of photoactivated adenylyl cyclase;
PDBTitle: structure of a bacterial light-regulated adenylyl cylcase
8c6r4oA_



100.0 20
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a truncated adenylyl cyclase bound to mant-gtp, forskolin2 and an activated stimulatory galphas protein
9c3mr7B_



100.0 23
PDB header:hydrolase
Chain: B: PDB Molecule:adenylate/guanylate cyclase/hydrolase, alpha/beta fold
PDBTitle: crystal structure of adenylate/guanylate cyclase/hydrolase from2 silicibacter pomeroyi
10c4cllA_



100.0 19
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase type 10;
PDBTitle: crystal structure of human soluble adenylyl cyclase in complex with2 bicarbonate
11c6r4pA_



100.0 21
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a soluble domain of adenylyl cyclase bound to an2 activated stimulatory g protein
12c4wp3E_



100.0 31
PDB header:lyase
Chain: E: PDB Molecule:ma1120;
PDBTitle: crystal structure of adenylyl cyclase from mycobacterium avium ma11202 wild type
13c5o5kC_



100.0 28
PDB header:membrane protein
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: x-ray structure of a bacterial adenylyl cyclase soluble domain
14c1wc6B_



100.0 26
PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate
15c1ybuA_



100.0 24
PDB header:hydrolase
Chain: A: PDB Molecule:lipj;
PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog.
16d1wc1a_



100.0 26
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
17c3uvjC_



100.0 23
PDB header:lyase
Chain: C: PDB Molecule:guanylate cyclase soluble subunit alpha-3;
PDBTitle: crystal structure of the catalytic domain of the heterodimeric human2 soluble guanylate cyclase 1.
18c1cjkA_



100.0 23
PDB header:lyase/lyase/signaling protein
Chain: A: PDB Molecule:adenylate cyclase, type v;
PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn
19c3r5gB_



100.0 23
PDB header:lyase
Chain: B: PDB Molecule:cyab;
PDBTitle: crystal structure of the adenylyl cyclase cyab from p. aeruginosa
20c2w01C_



100.0 20
PDB header:lyase
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the guanylyl cyclase cya2
21d1azsa_



not modelled 100.0 21
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
22c3et6A_



not modelled 100.0 28
PDB header:lyase
Chain: A: PDB Molecule:soluble guanylyl cyclase beta;
PDBTitle: the crystal structure of the catalytic domain of a eukaryotic2 guanylate cyclase
23c2wz1B_



not modelled 100.0 24
PDB header:lyase
Chain: B: PDB Molecule:guanylate cyclase soluble subunit beta-1;
PDBTitle: structure of the catalytic domain of human soluble guanylate cyclase 12 beta 3.
24d1azsb_



not modelled 100.0 27
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
25c1yk9A_



not modelled 100.0 31
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of a mutant form of the mycobacterial2 adenylyl cyclase rv1625c
26c6aoaA_



not modelled 99.9 23
PDB header:lyase
Chain: A: PDB Molecule:bacterio-rhodopsin/guanylyl cyclase 1 fusion protein;
PDBTitle: monomeric crystal structure of the e497/c566d double mutant of the2 guanylyl cyclase domain of the rhogc fusion protein from the aquatic3 fungus blastocladiella emersonii
27c4zmuD_



not modelled 96.2 10
PDB header:lyase
Chain: D: PDB Molecule:diguanylate cyclase;
PDBTitle: dcsbis, a diguanylate cyclase from pseudomonas aeruginosa
28c5llxB_



not modelled 95.7 11
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase (ggdef) domain-containing protein;
PDBTitle: bacteriophytochrome activated diguanylyl cyclase from idiomarina2 species a28l with gtp bound
29c5c8eC_



not modelled 95.5 14
PDB header:transcription regulator/dna
Chain: C: PDB Molecule:light-dependent transcriptional regulator carh;
PDBTitle: crystal structure of thermus thermophilus carh bound to2 adenosylcobalamin and a 26-bp dna segment
30c2qv6D_



not modelled 95.2 20
PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase iii;
PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions
31c1w25B_



not modelled 94.4 12
PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
32c4r4eA_



not modelled 94.1 10
PDB header:transcription regulator/dna
Chain: A: PDB Molecule:hth-type transcriptional regulator glnr;
PDBTitle: structure of glnr-dna complex
33c3ezuA_



not modelled 93.8 16
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution
34c4r24B_



not modelled 93.4 15
PDB header:transcrption/dna
Chain: B: PDB Molecule:hth-type transcriptional regulator tnra;
PDBTitle: complete dissection of b. subtilis nitrogen homeostatic circuitry
35c5af3A_



not modelled 93.2 11
PDB header:dna binding
Chain: A: PDB Molecule:vapbc49;
PDBTitle: x-ray crystal structure of rv2018 from mycobacterium tuberculosis
36c3hh0C_



not modelled 91.6 15
PDB header:transcription regulator
Chain: C: PDB Molecule:transcriptional regulator, merr family;
PDBTitle: crystal structure of a transcriptional regulator, merr family from2 bacillus cereus
37c5ydcA_



not modelled 91.2 15
PDB header:transcription regulator
Chain: A: PDB Molecule:uncharacterized hth-type transcriptional regulator rv1828;
PDBTitle: crystal structure of mercury soaked c-terminal domain of rv1828 from2 mycobacterium tuberculosis
38c6d9mA_



not modelled 91.1 14
PDB header:hydrolase
Chain: A: PDB Molecule:fusion protein of endolysin,response receiver sensor
PDBTitle: t4-lysozyme fusion to geobacter ggdef
39c3ignA_



not modelled 89.6 10
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of the ggdef domain from marinobacter aquaeolei2 diguanylate cyclase complexed with c-di-gmp - northeast structural3 genomics consortium target mqr89a
40c2zhhA_



not modelled 89.4 14
PDB header:transcription
Chain: A: PDB Molecule:redox-sensitive transcriptional activator soxr;
PDBTitle: crystal structure of soxr
41c4h54B_



not modelled 89.4 10
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase ydeh;
PDBTitle: crystal structure of the diguanylate cyclase dgcz
42c5i44E_



not modelled 88.5 13
PDB header:dna binding protein/dna
Chain: E: PDB Molecule:chromosome-anchoring protein raca;
PDBTitle: structure of raca-dna complex; p21 form
43c3mtkA_



not modelled 88.2 13
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c
44c5crlA_



not modelled 88.0 16
PDB header:metal binding protein
Chain: A: PDB Molecule:mercuric resistance operon regulatory protein;
PDBTitle: crystal structure of the transcription activator tn501 merr in complex2 with mercury (ii)
45d1r8da_



not modelled 87.4 18
Fold:Putative DNA-binding domain
Superfamily:Putative DNA-binding domain
Family:DNA-binding N-terminal domain of transcription activators
46c5gpeB_



not modelled 85.7 7
PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulator, merr-family;
PDBTitle: crystal structure of the transcription regulator pbrr691 from2 ralstonia metallidurans ch34 in complex with lead(ii)
47d1r8ea1



not modelled 85.5 14
Fold:Putative DNA-binding domain
Superfamily:Putative DNA-binding domain
Family:DNA-binding N-terminal domain of transcription activators
48c2vz4A_



not modelled 84.0 18
PDB header:transcription
Chain: A: PDB Molecule:hth-type transcriptional activator tipa;
PDBTitle: the n-terminal domain of merr-like protein tipal bound to promoter dna
49c4ymeA_



not modelled 83.5 16
PDB header:lyase
Chain: A: PDB Molecule:sensory box/ggdef family protein;
PDBTitle: crystal structure of a sensory box/ggdef family protein (cc_0091) from2 caulobacter crescentus cb15 at 1.40 a resolution (psi community3 target, shapiro)
50c6eibC_



not modelled 82.8 15
PDB header:transferase
Chain: C: PDB Molecule:sensory box/ggdef family protein;
PDBTitle: structure of the active ggeef domain of a diguanylate cyclase from2 vibrio cholerae.
51c4zvhB_



not modelled 82.3 15
PDB header:signaling protein
Chain: B: PDB Molecule:diguanylate cyclase dosc;
PDBTitle: crystal structure of ggdef domain of the e. coli dosc - form iv
52c3hvwA_



not modelled 81.4 12
PDB header:lyase
Chain: A: PDB Molecule:diguanylate-cyclase (dgc);
PDBTitle: crystal structure of the ggdef domain of the pa2567 protein from2 pseudomonas aeruginosa, northeast structural genomics consortium3 target par365c
53c2jmlA_



not modelled 80.3 25
PDB header:transcription
Chain: A: PDB Molecule:dna binding domain/transcriptional regulator;
PDBTitle: solution structure of the n-terminal domain of cara repressor
54c3hvaA_



not modelled 80.0 16
PDB header:transferase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx ggdef domain from pseudomonas aeruginosa
55c4iobA_



not modelled 79.9 13
PDB header:lyase
Chain: A: PDB Molecule:diguanylate cyclase tpbb;
PDBTitle: crystal structure of the ggdef domain of pa1120 (yfin or tpbb) from2 pseudomonas aeruginosa at 2.7 ang.
56c4wxoA_



not modelled 79.8 18
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: sadc (300-487) from pseudomonas aeruginosa pao1
57c3ucsB_



not modelled 77.4 19
PDB header:chaperone
Chain: B: PDB Molecule:chaperone-modulator protein cbpm;
PDBTitle: crystal structure of the complex between cbpa j-domain and cbpm
58c3gp4B_



not modelled 77.4 13
PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, merr family;
PDBTitle: crystal structure of putative merr family transcriptional regulator2 from listeria monocytogenes
59c3i5aA_



not modelled 76.1 20
PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
60c4zmmB_



not modelled 75.9 11
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: ggdef domain of dcsbis complexed with c-di-gmp
61c3breA_



not modelled 74.8 17
PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
62c4euvA_



not modelled 72.8 8
PDB header:signaling protein
Chain: A: PDB Molecule:peld;
PDBTitle: crystal structure of peld 158-ct from pseudomonas aeruginosa pao1, in2 complex with c-di-gmp, form 1
63d1q06a_



not modelled 70.7 10
Fold:Putative DNA-binding domain
Superfamily:Putative DNA-binding domain
Family:DNA-binding N-terminal domain of transcription activators
64c3gpvA_



not modelled 70.5 6
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, merr family;
PDBTitle: crystal structure of a transcriptional regulator, merr2 family from bacillus thuringiensis
65c3iclA_



not modelled 67.4 15
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium target mcr174c
66c6amaO_



not modelled 62.7 17
PDB header:dna binding protein/dna
Chain: O: PDB Molecule:putative dna-binding protein;
PDBTitle: structure of s. coelicolor/s. venezuelae bldc-smea-ssfa complex to2 3.09 angstrom
67c4j2nB_



not modelled 62.7 21
PDB header:viral protein
Chain: B: PDB Molecule:gp37;
PDBTitle: crystal structure of mycobacteriophage pukovnik xis
68c4j2nA_



not modelled 62.7 21
PDB header:viral protein
Chain: A: PDB Molecule:gp37;
PDBTitle: crystal structure of mycobacteriophage pukovnik xis
69d1w25a3



not modelled 62.1 11
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:GGDEF domain
70c4urgB_



not modelled 59.5 14
PDB header:lyase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of ggdef domain from t.maritima (active-like dimer)
71c3tvkA_



not modelled 58.3 10
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase dgcz;
PDBTitle: diguanylate cyclase domain of dgcz
72d1v6ta_



not modelled 57.9 16
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
73c2x5eA_



not modelled 54.8 20
PDB header:unknown function
Chain: A: PDB Molecule:upf0271 protein pa4511;
PDBTitle: crystal structure of the hypothetical protein pa4511 from2 pseudomonas aeruginosa
74c3qyyB_



not modelled 51.6 11
PDB header:signaling protein/inhibitor
Chain: B: PDB Molecule:response regulator;
PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp
75c3ungC_



not modelled 49.4 12
PDB header:unknown function
Chain: C: PDB Molecule:cmr2dhd;
PDBTitle: structure of the cmr2 subunit of the crispr rna silencing complex
76d2dfaa1



not modelled 44.7 23
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
77c3iwfA_



not modelled 43.1 14
PDB header:transcription regulator
Chain: A: PDB Molecule:transcription regulator rpir family;
PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a
78c4dmzB_



not modelled 41.6 8
PDB header:nucleotide-binding protein
Chain: B: PDB Molecule:putative uncharacterized protein peld;
PDBTitle: peld 156-455 from pseudomonas aeruginosa pa14, apo form
79c4w8yA_



not modelled 39.1 12
PDB header:rna binding protein
Chain: A: PDB Molecule:crispr system cmr subunit cmr2;
PDBTitle: structure of full length cmr2 from pyrococcus furiosus (manganese2 bound form)
80c5euhA_



not modelled 35.9 13
PDB header:membrane protein
Chain: A: PDB Molecule:putative ggdef domain membrane protein;
PDBTitle: crystal structure of the c-di-gmp-bound ggdef domain of p. fluorescens2 gcbc
81c3i5cA_



not modelled 35.2 15
PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa
82c4ua2B_



not modelled 29.6 16
PDB header:dna binding protein
Chain: B: PDB Molecule:regulatory protein;
PDBTitle: crystal structure of dual function transcriptional regulator merr from2 bacillus megaterium mb1
83c3qaoA_



not modelled 28.5 16
PDB header:transcription regulator
Chain: A: PDB Molecule:merr-like transcriptional regulator;
PDBTitle: the crystal structure of the n-terminal domain of a merr-like2 transcriptional regulator from listeria monocytogenes egd-e
84d2es9a1



not modelled 27.9 11
Fold:YoaC-like
Superfamily:YoaC-like
Family:YoaC-like
85c5m3cB_



not modelled 24.9 17
PDB header:hydrolase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: structure of the hybrid domain (ggdef-eal) of pa0575 from pseudomonas2 aeruginosa pao1 at 2.8 ang. with gtp and ca2+ bound to the active3 site of the ggdef domain
86c2y0fD_



not modelled 22.9 9
PDB header:oxidoreductase
Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase;
PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27
87c4ivnB_



not modelled 22.2 14
PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator;
PDBTitle: the vibrio vulnificus nanr protein complexed with mannac-6p
88c5xgdA_



not modelled 21.5 12
PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein pa0861;
PDBTitle: crystal structure of the pas-ggdef-eal domain of pa0861 from2 pseudomonas aeruginosa in complex with gtp
89c3noyA_



not modelled 21.2 24
PDB header:oxidoreductase
Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase;
PDBTitle: crystal structure of ispg (gcpe)
90d2p7vb1



not modelled 20.6 19
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
91c2dg6A_



not modelled 19.3 14
PDB header:gene regulation
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: crystal structure of the putative transcriptional regulator sco55502 from streptomyces coelicolor a3(2)
92c3pjwA_



not modelled 16.7 10
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
93c3i5bA_



not modelled 16.0 13
PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa
94c3t72o_



not modelled 15.8 19
PDB header:transcription/dna
Chain: O: PDB Molecule:pho box dna (strand 1);
PDBTitle: phob(e)-sigma70(4)-(rnap-betha-flap-tip-helix)-dna transcription2 activation sub-complex
95c5xqlA_



not modelled 15.2 6
PDB header:transcription
Chain: A: PDB Molecule:multidrug-efflux transporter 1 regulator;
PDBTitle: crystal structure of a pseudomonas aeruginosa transcriptional2 regulator
96c2o3fC_



not modelled 14.0 24
PDB header:transcription
Chain: C: PDB Molecule:putative hth-type transcriptional regulator ybbh;
PDBTitle: structural genomics, the crystal structure of the n-2 terminal domain of the putative transcriptional regulator3 ybbh from bacillus subtilis subsp. subtilis str. 168.
97d2o3fa1



not modelled 14.0 24
Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:RpiR-like
98d2tssa1



not modelled 13.8 33
Fold:OB-fold
Superfamily:Bacterial enterotoxins
Family:Superantigen toxins, N-terminal domain
99c2cwbA_



not modelled 13.3 24
PDB header:protein binding
Chain: A: PDB Molecule:chimera of immunoglobulin g binding protein g
PDBTitle: solution structure of the ubiquitin-associated domain of2 human bmsc-ubp and its complex with ubiquitin

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