1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	H	A	K	S	A	Y	P	D	G	I	A	D	H	D	R	P	L	A	P	R	G	I	R	E	A	G	L	A	G	G	W	L	R	A	N	L	P	A	V	D	A	V	L	C	S	T	A	T	R	A	R	Q	T	L	A	H	T	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	D	A	P	A	R	Y	A	E	R	L	Y	G	A	A	P	G	T	V	I	E	E	I	N	R	V	G	D	N	V	T	T	L	L	V	V	G	H	E	P	T	T	S	A	L	A	I	V	L	A	S	I	S	G	T	D	A	A	V	A
Secondary structure
SS confidence
Disorder																																																							?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
Sequence		E	R	I	S	E	K	F	P	T	S	G	I	A	V	L	R	V	A	G	H	W	A	D	V	E	P	G	C	A	A	L	V	G	F	H	V	P	R
Secondary structure
SS confidence
Disorder					?																																?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 15%) Alpha helix ( 36%) Beta strand ( 18%)

Rank Aligned region

PDB 4hbz chain A Region: 1 - 157 Aligned: 155 Modelled: 156 Confidence: 100.0% Identity: 44% PDB header:hydrolase, isomerase Chain: A: PDB Molecule:putative phosphohistidine phosphatase, sixa; PDBTitle: the structure of putative phosphohistidine phosphatase sixa from2 nakamurella multipartitia. Phyre2 PDB 2rfl chain B Region: 1 - 157 Aligned: 143 Modelled: 157 Confidence: 100.0% Identity: 32% PDB header:hydrolase, isomerase Chain: B: PDB Molecule:putative phosphohistidine phosphatase sixa; PDBTitle: crystal structure of the putative phosphohistidine phosphatase sixa2 from agrobacterium tumefaciens Phyre2 PDB 3f2i chain D Region: 1 - 158 Aligned: 149 Modelled: 158 Confidence: 100.0% Identity: 20% PDB header:structural genomics, unknown function Chain: D: PDB Molecule:alr0221 protein; PDBTitle: crystal structure of the alr0221 protein from nostoc, northeast2 structural genomics consortium target nsr422. Phyre2 PDB 1ujc chain A Region: 1 - 158 Aligned: 142 Modelled: 158 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:phosphohistidine phosphatase sixa; PDBTitle: structure of the protein histidine phosphatase sixa2 complexed with tungstate Phyre2 PDB 3mxo chain B Region: 1 - 154 Aligned: 142 Modelled: 154 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:serine/threonine-protein phosphatase pgam5, mitochondrial; PDBTitle: crystal structure oh human phosphoglycerate mutase family member 52 (pgam5) Phyre2 PDB 3d4i chain D Region: 1 - 148 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: D: PDB Molecule:sts-2 protein; PDBTitle: crystal structure of the 2h-phosphatase domain of sts-2 Phyre2 PDB 1e58 chain A Region: 1 - 140 Aligned: 135 Modelled: 140 Confidence: 100.0% Identity: 22% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 3fjy chain B Region: 1 - 156 Aligned: 149 Modelled: 156 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:probable mutt1 protein; PDBTitle: crystal structure of a probable mutt1 protein from bifidobacterium2 adolescentis Phyre2 PDB 3c7t chain B Region: 1 - 158 Aligned: 157 Modelled: 158 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:ecdysteroid-phosphate phosphatase; PDBTitle: crystal structure of the ecdysone phosphate phosphatase, eppase, from2 bombix mori in complex with tungstate Phyre2 PDB 5gg7 chain A Region: 1 - 157 Aligned: 143 Modelled: 157 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:hydrolase, nudix family protein; PDBTitle: crystal structure of mycobacterium smegmatis mutt1 in complex with 8-2 oxo-dgtp, 8-oxo-dgmp and pyrophosphate (i) Phyre2 PDB 2ikq chain A Region: 1 - 152 Aligned: 147 Modelled: 152 Confidence: 100.0% Identity: 27% PDB header:signaling protein, immune system Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1; PDBTitle: crystal structure of mouse sts-1 pgm domain in complex with phosphate Phyre2 PDB 1yjx chain D Region: 1 - 146 Aligned: 141 Modelled: 146 Confidence: 99.9% Identity: 26% PDB header:isomerase, hydrolase Chain: D: PDB Molecule:phosphoglycerate mutase 1; PDBTitle: crystal structure of human b type phosphoglycerate mutase Phyre2 PDB 2hhj chain A domain 1 Region: 1 - 146 Aligned: 141 Modelled: 146 Confidence: 99.9% Identity: 29% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 4emb chain D Region: 1 - 145 Aligned: 140 Modelled: 145 Confidence: 99.9% Identity: 26% PDB header:isomerase Chain: D: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of a phosphoglycerate mutase gpma from borrelia2 burgdorferi b31 Phyre2 PDB 1rii chain A Region: 1 - 147 Aligned: 142 Modelled: 147 Confidence: 99.9% Identity: 24% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 4pz9 chain B Region: 1 - 155 Aligned: 147 Modelled: 151 Confidence: 99.9% Identity: 20% PDB header:hydrolase Chain: B: PDB Molecule:glucosyl-3-phosphoglycerate phosphatase; PDBTitle: the native structure of mycobacterial glucosyl-3-phosphoglycerate2 phosphatase rv2419c Phyre2 PDB 3ezn chain B Region: 1 - 145 Aligned: 140 Modelled: 145 Confidence: 99.9% Identity: 25% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglyceromutase from burkholderia2 pseudomallei 1710b Phyre2 PDB 5um0 chain A Region: 1 - 140 Aligned: 135 Modelled: 140 Confidence: 99.9% Identity: 28% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of 2,3-bisphosphoglycerate-dependent2 phosphoglycerate mutase from neisseria gonorrhoeae Phyre2 PDB 1qhf chain A Region: 1 - 147 Aligned: 142 Modelled: 147 Confidence: 99.9% Identity: 25% Fold: Phosphoglycerate mutase-like Superfamily: Phosphoglycerate mutase-like Family: Cofactor-dependent phosphoglycerate mutase Phyre2 PDB 2a6p chain A Region: 1 - 154 Aligned: 141 Modelled: 154 Confidence: 99.9% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:possible phosphoglycerate mutase gpm2; PDBTitle: structure solution to 2.2 angstrom and functional characterisation of2 the open reading frame rv3214 from mycobacterium tuberculosis Phyre2 1 c4hbzA_ 2 c2rflB_ 3 c3f2iD_ 4 c1ujcA_ 5 c3mxoB_ 6 c3d4iD_ 7 d1e58a_ 8 c3fjyB_ 9 c3c7tB_ 10 c5gg7A_ 11 c2ikqA_ 12 c1yjxD_ 13 d2hhja1 14 c4embD_ 15 d1riia_ 16 c4pz9B_ 17 c3eznB_ 18 c5um0A_ 19 d1qhfa_ 20 c2a6pA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99