1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	E	F	A	S	R	R	T	L	V	V	R	R	F	L	R	N	R	A	A	V	A	S	L	A	A	L	L	L	L	F	V	S	A	Y	A	L	P	P	L	L	P	Y	S	Y	D	D	L	D	F	N	A	L	L	Q	P	P	G	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	H	W	L	G	T	N	A	L	G	Q	D	L	L	A	Q	T	L	R	G	M	Q	K	S	M	L	I	G	V	C	V	A	V	I	S	T	G	I	A	A	T	V	G	A	I	S	G	Y	F	G	G	W	R	D	R	T	L	M	W	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	D	L	L	L	V	V	P	S	F	I	L	I	A	I	V	T	P	R	T	K	N	S	A	N	I	M	F	L	V	L	L	L	A	G	F	G	W	M	I	S	S	R	M	V	R	G	M	T	M	S	L	R	E	R	E	F	I	R	A
Secondary structure
SS confidence
Disorder																						?			?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	R	Y	M	G	V	S	S	R	R	I	I	V	G	H	V	V	P	N	V	A	S	I	L	I	I	D	A	A	L	N	V	A	A	A	I	L	A	E	T	G	L	S	F	L	G	F	G	I	Q	P	P	D	V	S	L	G	T	L	I
Secondary structure
SS confidence
Disorder									?																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
Sequence		A	D	G	T	A	S	A	T	A	F	P	W	V	F	L	F	P	A	S	I	L	V	L	I	L	V	C	A	N	L	T	G	D	G	L	R	D	A	L	D	P	A	S	R	S	L	R	R	G	V	R
Secondary structure
SS confidence
Disorder																																											?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 80%) Beta strand ( 0%) TM helix ( 48%) (View membrane topology prediction)

Rank Aligned region

PDB 4ymu chain C Region: 72 - 279 Aligned: 202 Modelled: 208 Confidence: 99.9% Identity: 7% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 4tqv chain I Region: 9 - 281 Aligned: 261 Modelled: 272 Confidence: 99.9% Identity: 10% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 3fh6 chain F Region: 8 - 290 Aligned: 273 Modelled: 283 Confidence: 99.9% Identity: 10% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 2onk chain C Region: 14 - 275 Aligned: 238 Modelled: 244 Confidence: 99.9% Identity: 15% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 14 - 275 Aligned: 238 Modelled: 244 Confidence: 99.9% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3dhw chain A domain 1 Region: 77 - 273 Aligned: 190 Modelled: 197 Confidence: 99.9% Identity: 17% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain C domain 1 Region: 20 - 271 Aligned: 229 Modelled: 235 Confidence: 99.9% Identity: 17% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 20 - 271 Aligned: 229 Modelled: 235 Confidence: 99.9% Identity: 17% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 2r6g chain F domain 2 Region: 68 - 271 Aligned: 204 Modelled: 204 Confidence: 99.9% Identity: 13% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain J Region: 16 - 273 Aligned: 256 Modelled: 258 Confidence: 99.9% Identity: 11% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F Region: 57 - 271 Aligned: 215 Modelled: 215 Confidence: 99.9% Identity: 13% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 2r6g chain G domain 1 Region: 13 - 289 Aligned: 265 Modelled: 277 Confidence: 99.9% Identity: 12% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5kbu chain A Region: 83 - 288 Aligned: 164 Modelled: 173 Confidence: 96.3% Identity: 18% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2jwa chain A Region: 83 - 115 Aligned: 33 Modelled: 33 Confidence: 24.6% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-2; PDBTitle: erbb2 transmembrane segment dimer spatial structure Phyre2 PDB 2ks1 chain A Region: 83 - 115 Aligned: 33 Modelled: 33 Confidence: 24.6% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-2; PDBTitle: heterodimeric association of transmembrane domains of erbb1 and erbb22 receptors enabling kinase activation Phyre2 PDB 2nd4 chain A Region: 162 - 185 Aligned: 24 Modelled: 24 Confidence: 21.6% Identity: 25% PDB header:hydrolase receptor Chain: A: PDB Molecule:amylase-binding protein abpa; PDBTitle: a distinct sortase srtb anchors and processes a streptococcal adhesin2 abpa with a novel structural property Phyre2 PDB 6o7x chain A Region: 24 - 148 Aligned: 125 Modelled: 125 Confidence: 16.3% Identity: 10% PDB header:membrane protein Chain: A: PDB Molecule:vacuolar atp synthase catalytic subunit a; PDBTitle: saccharomyces cerevisiae v-atpase stv1-v1vo state 3 Phyre2 PDB 5gas chain N Region: 26 - 272 Aligned: 175 Modelled: 178 Confidence: 13.5% Identity: 16% PDB header:hydrolase Chain: N: PDB Molecule:archaeal/vacuolar-type h+-atpase subunit i; PDBTitle: thermus thermophilus v/a-atpase, conformation 2 Phyre2 PDB 3k07 chain A Region: 72 - 291 Aligned: 191 Modelled: 206 Confidence: 10.9% Identity: 15% PDB header:transport protein Chain: A: PDB Molecule:cation efflux system protein cusa; PDBTitle: crystal structure of cusa Phyre2 PDB 6b8h chain B Region: 229 - 289 Aligned: 61 Modelled: 61 Confidence: 10.7% Identity: 10% PDB header:membrane protein Chain: B: PDB Molecule:atp synthase subunit alpha, mitochondrial; PDBTitle: mosaic model of yeast mitochondrial atp synthase monomer Phyre2 1 c4ymuC_ 2 c4tqvI_ 3 c3fh6F_ 4 c2onkC_ 5 d2onkc1 6 d3dhwa1 7 d3d31c1 8 c3d31D_ 9 d2r6gf2 10 c4tqvJ_ 11 c2r6gF_ 12 d2r6gg1 13 c5kbuA_ 14 c2jwaA_ 15 c2ks1A_ 16 c2nd4A_ 17 c6o7xa_ 18 c5gasN_ 19 c3k07A_ 20 c6b8hb_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34