1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	R	Y	L	A	R	R	L	L	N	Y	L	V	L	L	A	L	A	S	F	L	T	Y	C	L	T	S	L	A	F	S	P	L	E	S	L	M	Q	R	S	P	R	P	P	Q	A	V	I	D	A	K	A	H	D	L	G	L	D	R
Secondary structure
SS confidence
Disorder		?																																						?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	I	L	A	R	Y	A	N	W	V	S	H	A	V	R	G	D	F	G	T	T	I	T	G	Q	P	V	G	T	E	L	G	R	R	I	G	V	S	L	R	L	L	V	V	G	S	V	F	G	T	V	A	G	V	V	I	G	A	W	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	I	R	Q	Y	R	L	S	D	R	V	M	T	T	L	A	L	L	V	L	S	T	P	T	F	V	V	A	N	L	L	I	L	G	A	L	R	V	N	W	A	V	G	I	Q	L	F	D	Y	T	G	E	T	S	P	G	V	A	G	G
Secondary structure
SS confidence
Disorder																																						?	?	?														?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	W	D	R	L	G	D	R	L	Q	H	L	I	L	P	S	L	T	L	A	L	A	A	A	A	G	F	S	R	Y	Q	R	N	A	M	L	D	V	L	G	Q	D	F	I	R	T	A	R	A	K	G	L	T	R	R	R	A	L	L	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	G	L	R	T	A	L	I	P	M	A	T	L	F	A	Y	G	V	A	G	L	V	T	G	A	V	F	V	E	K	I	F	G	W	H	G	M	G	E	W	M	V	R	G	I	S	T	Q	D	T	N	I	V	A	A	I	T	V	F	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.
Sequence		G	A	V	V	L	L	A	G	L	L	S	D	V	I	Y	A	A	L	D	P	R	V	R	V	S
Secondary structure
SS confidence
Disorder																								?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 74%) Beta strand ( 0%) TM helix ( 46%) (View membrane topology prediction)

Rank Aligned region

PDB 4ymu chain C Region: 75 - 323 Aligned: 214 Modelled: 221 Confidence: 99.9% Identity: 14% PDB header:protein binding/transport protein Chain: C: PDB Molecule:abc-type amino acid transport system, permease component; PDBTitle: crystal structure of an amino acid abc transporter complex with2 arginines and atps Phyre2 PDB 3dhw chain A domain 1 Region: 90 - 312 Aligned: 194 Modelled: 196 Confidence: 99.9% Identity: 21% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 3d31 chain D Region: 89 - 311 Aligned: 204 Modelled: 206 Confidence: 99.8% Identity: 13% PDB header:transport protein Chain: D: PDB Molecule:sulfate/molybdate abc transporter, permease protein; PDBTitle: modbc from methanosarcina acetivorans Phyre2 PDB 3d31 chain C domain 1 Region: 89 - 311 Aligned: 204 Modelled: 206 Confidence: 99.8% Identity: 13% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2onk chain C Region: 89 - 314 Aligned: 205 Modelled: 207 Confidence: 99.8% Identity: 9% PDB header:membrane protein Chain: C: PDB Molecule:molybdate/tungstate abc transporter, permease PDBTitle: abc transporter modbc in complex with its binding protein2 moda Phyre2 PDB 2onk chain C domain 1 Region: 89 - 314 Aligned: 205 Modelled: 207 Confidence: 99.8% Identity: 9% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 4tqv chain I Region: 89 - 319 Aligned: 222 Modelled: 231 Confidence: 99.8% Identity: 14% PDB header:transport protein Chain: I: PDB Molecule:algm1; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain F domain 2 Region: 77 - 310 Aligned: 224 Modelled: 234 Confidence: 99.6% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 2r6g chain F Region: 69 - 310 Aligned: 232 Modelled: 242 Confidence: 99.5% Identity: 12% PDB header:hydrolase/transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: the crystal structure of the e. coli maltose transporter Phyre2 PDB 3fh6 chain F Region: 1 - 311 Aligned: 286 Modelled: 311 Confidence: 99.5% Identity: 13% PDB header:transport protein Chain: F: PDB Molecule:maltose transport system permease protein malf; PDBTitle: crystal structure of the resting state maltose transporter from e.2 coli Phyre2 PDB 4tqv chain J Region: 7 - 312 Aligned: 249 Modelled: 255 Confidence: 99.2% Identity: 17% PDB header:transport protein Chain: J: PDB Molecule:algm2; PDBTitle: crystal structure of a bacterial abc transporter involved in the2 import of the acidic polysaccharide alginate Phyre2 PDB 2r6g chain G domain 1 Region: 6 - 311 Aligned: 260 Modelled: 283 Confidence: 99.0% Identity: 15% Fold: MetI-like Superfamily: MetI-like Family: MetI-like Phyre2 PDB 5kbu chain A Region: 41 - 320 Aligned: 207 Modelled: 213 Confidence: 94.3% Identity: 16% PDB header:transport protein Chain: A: PDB Molecule:glutamate receptor 2,voltage-dependent calcium channel PDBTitle: cryo-em structure of glua2-2xstz complex at 7.8 angstrom resolution Phyre2 PDB 2nd4 chain A Region: 211 - 231 Aligned: 21 Modelled: 21 Confidence: 59.8% Identity: 43% PDB header:hydrolase receptor Chain: A: PDB Molecule:amylase-binding protein abpa; PDBTitle: a distinct sortase srtb anchors and processes a streptococcal adhesin2 abpa with a novel structural property Phyre2 PDB 5xu1 chain M Region: 182 - 320 Aligned: 132 Modelled: 139 Confidence: 45.1% Identity: 14% PDB header:transport protein Chain: M: PDB Molecule:abc transporter permeae; PDBTitle: structure of a non-canonical abc transporter from streptococcus2 pneumoniae r6 Phyre2 PDB 5nik chain K Region: 183 - 320 Aligned: 127 Modelled: 138 Confidence: 32.4% Identity: 16% PDB header:transport protein Chain: K: PDB Molecule:macrolide export atp-binding/permease protein macb; PDBTitle: structure of the macab-tolc abc-type tripartite multidrug efflux pump Phyre2 PDB 5lj7 chain B Region: 182 - 320 Aligned: 128 Modelled: 139 Confidence: 31.6% Identity: 16% PDB header:transport protein Chain: B: PDB Molecule:macrolide export atp-binding/permease protein macb; PDBTitle: structure of aggregatibacter actinomycetemcomitans macb bound to atp2 (p21) Phyre2 PDB 1wz4 chain A Region: 315 - 323 Aligned: 9 Modelled: 9 Confidence: 22.6% Identity: 78% PDB header:gene regulation Chain: A: PDB Molecule:major surface antigen; PDBTitle: solution conformation of adr subtype hbv pre-s2 epitope Phyre2 PDB 2yev chain C Region: 299 - 322 Aligned: 24 Modelled: 24 Confidence: 19.6% Identity: 33% PDB header:electron transport Chain: C: PDB Molecule:caa3-type cytochrome oxidase subunit iv; PDBTitle: structure of caa3-type cytochrome oxidase Phyre2 PDB 5l75 chain F Region: 3 - 155 Aligned: 109 Modelled: 114 Confidence: 16.9% Identity: 20% PDB header:transport protein Chain: F: PDB Molecule:fig000988: predicted permease; PDBTitle: a protein structure Phyre2 1 c4ymuC_ 2 d3dhwa1 3 c3d31D_ 4 d3d31c1 5 c2onkC_ 6 d2onkc1 7 c4tqvI_ 8 d2r6gf2 9 c2r6gF_ 10 c3fh6F_ 11 c4tqvJ_ 12 d2r6gg1 13 c5kbuA_ 14 c2nd4A_ 15 c5xu1M_ 16 c5nikK_ 17 c5lj7B_ 18 c1wz4A_ 19 c2yevC_ 20 c5l75F_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59