1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	T	R	R	F	A	A	S	M	V	G	T	T	L	T	A	A	T	L	G	L	A	A	L	G	F	A	G	T	A	S	A	S	S	T	D	E	A	F	L	A	Q	L	Q	A	D	G	I	T	P	P	S	A	A	R	A	I	K	D
Secondary structure
SS confidence
Disorder		?	?																									?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.
Sequence		A	H	A	V	C	D	A	L	D	E	G	H	S	A	K	A	V	I	K	A	V	A	K	A	T	G	L	S	A	K	G	A	K	T	F	A	V	D	A	A	S	A	Y	C	P	Q	Y	V	T	S	S
Secondary structure
SS confidence
Disorder											?															?	?	?	?																		?		?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 71%) Beta strand ( 0%) TM helix ( 14%) (View membrane topology prediction)

Rank Aligned region

PDB 6c3r chain B Region: 65 - 111 Aligned: 47 Modelled: 47 Confidence: 60.0% Identity: 19% PDB header:viral protein Chain: B: PDB Molecule:cricket paralysis virus 1a protein; PDBTitle: cricket paralysis virus rnai suppressor protein crpv-1a Phyre2 PDB 2csu chain A domain 3 Region: 34 - 60 Aligned: 27 Modelled: 27 Confidence: 25.7% Identity: 19% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 2ekc chain A Region: 34 - 83 Aligned: 48 Modelled: 50 Confidence: 16.8% Identity: 23% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 Phyre2 PDB 1mke chain A domain 1 Region: 48 - 70 Aligned: 23 Modelled: 23 Confidence: 15.8% Identity: 26% Fold: PH domain-like barrel Superfamily: PH domain-like Family: Enabled/VASP homology 1 domain (EVH1 domain) Phyre2 PDB 5k9x chain A Region: 48 - 83 Aligned: 34 Modelled: 32 Confidence: 15.8% Identity: 24% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of tryptophan synthase alpha chain from legionella2 pneumophila subsp. pneumophila Phyre2 PDB 4rl6 chain A Region: 10 - 51 Aligned: 40 Modelled: 42 Confidence: 14.9% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: crystal structure of the q04l03_strp2 protein from streptococcus2 pneumoniae. northeast structural genomics consortium target spr105 Phyre2 PDB 4ina chain A Region: 9 - 51 Aligned: 41 Modelled: 43 Confidence: 14.8% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: crystal structure of the q7mss8_wolsu protein from wolinella2 succinogenes. northeast structural genomics consortium target wsr35 Phyre2 PDB 5uqd chain A Region: 37 - 52 Aligned: 16 Modelled: 16 Confidence: 14.1% Identity: 31% PDB header:oxidoreductase Chain: A: PDB Molecule:dumpy: shorter than wild-type; PDBTitle: dpy-21 in complex with fe(ii) and alpha-ketoglutarate Phyre2 PDB 5tch chain G Region: 34 - 83 Aligned: 48 Modelled: 50 Confidence: 13.8% Identity: 25% PDB header:lyase Chain: G: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of tryptophan synthase from m. tuberculosis -2 ligand-free form, trpa-g66v mutant Phyre2 PDB 2jd3 chain B Region: 64 - 89 Aligned: 26 Modelled: 26 Confidence: 12.8% Identity: 27% PDB header:dna binding protein Chain: B: PDB Molecule:stbb protein; PDBTitle: parr from plasmid pb171 Phyre2 PDB 3ss4 chain C Region: 39 - 54 Aligned: 16 Modelled: 16 Confidence: 9.8% Identity: 19% PDB header:hydrolase Chain: C: PDB Molecule:glutaminase c; PDBTitle: crystal structure of mouse glutaminase c, phosphate-bound form Phyre2 PDB 5dgg chain B Region: 29 - 50 Aligned: 22 Modelled: 22 Confidence: 9.5% Identity: 27% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: central domain of uncharacterized lpg1148 protein from legionella2 pneumophila Phyre2 PDB 2j9g chain A domain 2 Region: 35 - 61 Aligned: 27 Modelled: 27 Confidence: 8.5% Identity: 22% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 5us3 chain A Region: 103 - 106 Aligned: 4 Modelled: 4 Confidence: 8.4% Identity: 75% PDB header:de novo protein Chain: A: PDB Molecule:heterogeneous-backbone variant of the sp1-3 zinc finger: n- PDBTitle: heterogeneous-backbone foldamer mimic of the sp1-3 zinc finger Phyre2 PDB 3g2b chain A Region: 60 - 94 Aligned: 35 Modelled: 35 Confidence: 8.3% Identity: 20% PDB header:biosynthetic protein Chain: A: PDB Molecule:coenzyme pqq synthesis protein d; PDBTitle: crystal structure of pqqd from xanthomonas campestris Phyre2 PDB 1ulz chain A domain 2 Region: 35 - 61 Aligned: 27 Modelled: 27 Confidence: 7.8% Identity: 19% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: BC N-terminal domain-like Phyre2 PDB 2lwe chain A Region: 38 - 52 Aligned: 15 Modelled: 15 Confidence: 7.8% Identity: 7% PDB header:signaling protein Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx58; PDBTitle: solution structure of mutant (t170e) second card of human rig-i Phyre2 PDB 1qcr chain D domain 2 Region: 47 - 70 Aligned: 24 Modelled: 24 Confidence: 7.6% Identity: 21% Fold: Cytochrome c Superfamily: Cytochrome c Family: Cytochrome bc1 domain Phyre2 PDB 1apz chain B Region: 60 - 83 Aligned: 24 Modelled: 24 Confidence: 7.6% Identity: 8% PDB header:complex (hydrolase/peptide) Chain: B: PDB Molecule:aspartylglucosaminidase; PDBTitle: human aspartylglucosaminidase complex with reaction product Phyre2 PDB 1vjq chain B Region: 33 - 51 Aligned: 19 Modelled: 19 Confidence: 7.5% Identity: 42% PDB header:structural genomics, de novo protein Chain: B: PDB Molecule:designed protein; PDBTitle: designed protein based on backbone conformation of2 procarboxypeptidase-a (1aye) with sidechains chosen for maximal3 predicted stability. Phyre2 1 c6c3rB_ 2 d2csua3 3 c2ekcA_ 4 d1mkea1 5 c5k9xA_ 6 c4rl6A_ 7 c4inaA_ 8 c5uqdA_ 9 c5tchG_ 10 c2jd3B_ 11 c3ss4C_ 12 c5dggB_ 13 d2j9ga2 14 c5us3A_ 15 c3g2bA_ 16 d1ulza2 17 c2lweA_ 18 d1qcrd2 19 c1apzB_ 20 c1vjqB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48