1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	E	L	N	V	E	I	V	A	V	D	R	N	I	W	S	G	T	A	K	F	L	F	T	R	T	T	V	G	E	I	G	I	L	P	R	H	I	P	L	V	A	Q	L	V	D	D	A	M	V	R	V	E	R	E	G	E	K	D
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	R	I	A	V	D	G	G	F	L	S	V	T	E	E	G	V	S	I	L	A	E	S	A	E	F	E	S	E	I	D	E	A	A	A	K	Q	D	S	E	S	D	D	P	R	I	A	A	R	G	R	A	R	L	R	A	V	G	A	I
Secondary structure
SS confidence
Disorder																															?																												?	?	?
Disorder confidence
		.
Sequence		D
Secondary structure
SS confidence
Disorder		?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 7%) Alpha helix ( 25%) Beta strand ( 52%)

Rank Aligned region

PDB 5yio chain A Region: 1 - 121 Aligned: 121 Modelled: 121 Confidence: 100.0% Identity: 100% PDB header:proton transport Chain: A: PDB Molecule:atp synthase epsilon chain; PDBTitle: nmr solution structure of subunit epsilon of the mycobacterium2 tuberculosis f-atp synthase Phyre2 PDB 6q45 chain P Region: 1 - 119 Aligned: 119 Modelled: 119 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: P: PDB Molecule:atp synthase epsilon chain; PDBTitle: f1-atpase from fusobacterium nucleatum Phyre2 PDB 2e5y chain A Region: 1 - 119 Aligned: 117 Modelled: 119 Confidence: 100.0% Identity: 38% PDB header:hydrolase Chain: A: PDB Molecule:atp synthase epsilon chain; PDBTitle: epsilon subunit and atp complex of f1f0-atp synthase from2 the thermophilic bacillus ps3 Phyre2 PDB 2rq7 chain A Region: 3 - 120 Aligned: 116 Modelled: 118 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:atp synthase epsilon chain; PDBTitle: solution structure of the epsilon subunit chimera combining2 the n-terminal beta-sandwich domain from t. elongatus bp-13 f1 and the c-terminal alpha-helical domain from spinach4 chloroplast f1 Phyre2 PDB 6fkh chain E Region: 1 - 117 Aligned: 114 Modelled: 115 Confidence: 100.0% Identity: 32% PDB header:membrane protein Chain: E: PDB Molecule:atp synthase subunit alpha, chloroplastic; PDBTitle: chloroplast f1fo conformation 2 Phyre2 PDB 1fs0 chain E Region: 3 - 118 Aligned: 115 Modelled: 116 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: E: PDB Molecule:atp synthase epsilon subunit; PDBTitle: complex of gamma/epsilon atp synthase from e.coli Phyre2 PDB 6f5d chain H Region: 1 - 120 Aligned: 119 Modelled: 120 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: H: PDB Molecule:atp synthase subunit delta, mitochondrial; PDBTitle: trypanosoma brucei f1-atpase Phyre2 PDB 2qe7 chain H Region: 1 - 119 Aligned: 117 Modelled: 119 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: H: PDB Molecule:atp synthase subunit epsilon; PDBTitle: crystal structure of the f1-atpase from the thermoalkaliphilic2 bacterium bacillus sp. ta2.a1 Phyre2 PDB 6ref chain R Region: 3 - 121 Aligned: 117 Modelled: 119 Confidence: 100.0% Identity: 21% PDB header:proton transport Chain: R: PDB Molecule:mitochondrial atp synthase subunit delta; PDBTitle: cryo-em structure of polytomella f-atp synthase, rotary substate 3b,2 monomer-masked refinement Phyre2 PDB 2wss chain Q Region: 3 - 120 Aligned: 117 Modelled: 118 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: Q: PDB Molecule:atp synthase subunit delta, mitochondrial; PDBTitle: the structure of the membrane extrinsic region of bovine atp synthase Phyre2 PDB 5lqz chain H Region: 5 - 120 Aligned: 115 Modelled: 116 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: H: PDB Molecule:atp synthase delta subunit; PDBTitle: structure of f-atpase from pichia angusta, state1 Phyre2 PDB 2hld chain H Region: 5 - 120 Aligned: 112 Modelled: 115 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: H: PDB Molecule:atp synthase delta chain, mitochondrial; PDBTitle: crystal structure of yeast mitochondrial f1-atpase Phyre2 PDB 1aqt chain A domain 2 Region: 2 - 87 Aligned: 85 Modelled: 86 Confidence: 99.9% Identity: 25% Fold: Epsilon subunit of F1F0-ATP synthase N-terminal domain Superfamily: Epsilon subunit of F1F0-ATP synthase N-terminal domain Family: Epsilon subunit of F1F0-ATP synthase N-terminal domain Phyre2 PDB 1h8e chain H Region: 3 - 90 Aligned: 87 Modelled: 88 Confidence: 99.9% Identity: 22% PDB header:hydrolase Chain: H: PDB Molecule:bovine mitochondrial f1-atpase; PDBTitle: (adp.alf4)2(adp.so4) bovine f1-atpase2 (all three catalytic sites occupied) Phyre2 PDB 5dn6 chain I Region: 9 - 83 Aligned: 74 Modelled: 75 Confidence: 99.9% Identity: 27% PDB header:hydrolase Chain: I: PDB Molecule:atp synthase epsilon chain; PDBTitle: atp synthase from paracoccus denitrificans Phyre2 PDB 2w6j chain H Region: 6 - 120 Aligned: 75 Modelled: 98 Confidence: 97.7% Identity: 27% PDB header:hydrolase Chain: H: PDB Molecule:f1-atpase delta subunit; PDBTitle: low resolution structures of bovine mitochondrial f1-atpase during2 controlled dehydration: hydration state 5. Phyre2 PDB 2e5t chain A Region: 90 - 119 Aligned: 30 Modelled: 30 Confidence: 91.2% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:atp synthase epsilon chain; PDBTitle: c-terminal domain of epsilon subunit of f1f0-atp synthase2 from the thermophilic bacillus ps3 in the presence of atp3 condition Phyre2 PDB 1aqt chain A domain 1 Region: 88 - 118 Aligned: 31 Modelled: 31 Confidence: 78.5% Identity: 39% Fold: Long alpha-hairpin Superfamily: Epsilon subunit of F1F0-ATP synthase C-terminal domain Family: Epsilon subunit of F1F0-ATP synthase C-terminal domain Phyre2 PDB 3hqx chain A Region: 5 - 85 Aligned: 81 Modelled: 81 Confidence: 59.2% Identity: 12% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0345 protein aciad0356; PDBTitle: crystal structure of protein of unknown function (duf1255,pf06865)2 from acinetobacter sp. adp1 Phyre2 PDB 4cv7 chain A Region: 5 - 35 Aligned: 31 Modelled: 31 Confidence: 23.3% Identity: 16% PDB header:toxin Chain: A: PDB Molecule:virulence associated protein vapb; PDBTitle: crystal structure of rhodococcus equi vapb Phyre2 1 c5yioA_ 2 c6q45P_ 3 c2e5yA_ 4 c2rq7A_ 5 c6fkhe_ 6 c1fs0E_ 7 c6f5dH_ 8 c2qe7H_ 9 c6refR_ 10 c2wssQ_ 11 c5lqzH_ 12 c2hldH_ 13 d1aqta2 14 c1h8eH_ 15 c5dn6I_ 16 c2w6jH_ 17 c2e5tA_ 18 d1aqta1 19 c3hqxA_ 20 c4cv7A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47