Phyre Home Retrieve Phyre Job Id
Emailmdejesus@rockefeller.edu
DescriptionRVBD1318c_(-)_1479205_1480830
DateWed Jul 31 22:05:41 BST 2019
Unique Job ID98a6c05f894ffcb1
SequenceMSAKKSTAQR ... Download FASTA
Job Typenormal
Job Expiry

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:69.189 Y:50.297 Z:48.159
Model (left) based on template c6fhtB_
Top template information
PDB header:lyase
Chain: B: PDB Molecule:bacteriophytochrome,adenylate cyclase;
PDBTitle: crystal structure of an artificial phytochrome regulated2 adenylate/guanylate cyclase in its dark adapted pr form
Confidence and coverage
Confidence:100.0% Coverage: 42%
226 residues ( 42% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
412 residues ( 76%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
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Sequence analysis 

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Secondary structure and disorder prediction [Show] 

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Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c6fhtB_
100.0 30
PDB header:lyase
Chain: B: PDB Molecule:bacteriophytochrome,adenylate cyclase;
PDBTitle: crystal structure of an artificial phytochrome regulated2 adenylate/guanylate cyclase in its dark adapted pr form
2c4yusA_
100.0 24
PDB header:lyase
Chain: A: PDB Molecule:family 3 adenylate cyclase;
PDBTitle: crystal structure of photoactivated adenylyl cyclase of a2 cyanobacteriaoscillatoria acuminata in hexagonal form
3c6r4oA_
100.0 16
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a truncated adenylyl cyclase bound to mant-gtp, forskolin2 and an activated stimulatory galphas protein
4c5nbyA_
100.0 23
PDB header:lyase
Chain: A: PDB Molecule:beta subunit of photoactivated adenylyl cyclase;
PDBTitle: structure of a bacterial light-regulated adenylyl cylcase
5c4cllA_
100.0 24
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase type 10;
PDBTitle: crystal structure of human soluble adenylyl cyclase in complex with2 bicarbonate
6c5o5kC_
100.0 26
PDB header:membrane protein
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: x-ray structure of a bacterial adenylyl cyclase soluble domain
7c6r4pA_
100.0 19
PDB header:membrane protein
Chain: A: PDB Molecule:adenylate cyclase 9;
PDBTitle: structure of a soluble domain of adenylyl cyclase bound to an2 activated stimulatory g protein
8c1y10C_
100.0 20
PDB header:lyase
Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state
9c2w01C_
100.0 30
PDB header:lyase
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the guanylyl cyclase cya2
10c1wc6B_
100.0 32
PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate
11d1wc1a_
100.0 33
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
12c3r5gB_
100.0 25
PDB header:lyase
Chain: B: PDB Molecule:cyab;
PDBTitle: crystal structure of the adenylyl cyclase cyab from p. aeruginosa
13c1cjkA_
100.0 17
PDB header:lyase/lyase/signaling protein
Chain: A: PDB Molecule:adenylate cyclase, type v;
PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn
14d1azsa_
100.0 17
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
15d1fx2a_
100.0 18
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
16c3uvjC_
100.0 19
PDB header:lyase
Chain: C: PDB Molecule:guanylate cyclase soluble subunit alpha-3;
PDBTitle: crystal structure of the catalytic domain of the heterodimeric human2 soluble guanylate cyclase 1.
17d1fx4a_
100.0 19
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
18c3et6A_
100.0 21
PDB header:lyase
Chain: A: PDB Molecule:soluble guanylyl cyclase beta;
PDBTitle: the crystal structure of the catalytic domain of a eukaryotic2 guanylate cyclase
19c3mr7B_
100.0 23
PDB header:hydrolase
Chain: B: PDB Molecule:adenylate/guanylate cyclase/hydrolase, alpha/beta fold
PDBTitle: crystal structure of adenylate/guanylate cyclase/hydrolase from2 silicibacter pomeroyi
20c2wz1B_
100.0 21
PDB header:lyase
Chain: B: PDB Molecule:guanylate cyclase soluble subunit beta-1;
PDBTitle: structure of the catalytic domain of human soluble guanylate cyclase 12 beta 3.
21c1ybuA_
not modelled 99.9 29
PDB header:hydrolase
Chain: A: PDB Molecule:lipj;
PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog.
22d1azsb_
not modelled 99.9 19
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
23c1yk9A_
not modelled 99.9 26
PDB header:lyase
Chain: A: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of a mutant form of the mycobacterial2 adenylyl cyclase rv1625c
24c4wp3E_
not modelled 99.9 28
PDB header:lyase
Chain: E: PDB Molecule:ma1120;
PDBTitle: crystal structure of adenylyl cyclase from mycobacterium avium ma11202 wild type
25c6aoaA_
not modelled 99.9 24
PDB header:lyase
Chain: A: PDB Molecule:bacterio-rhodopsin/guanylyl cyclase 1 fusion protein;
PDBTitle: monomeric crystal structure of the e497/c566d double mutant of the2 guanylyl cyclase domain of the rhogc fusion protein from the aquatic3 fungus blastocladiella emersonii
26c5jefA_
not modelled 98.9 19
PDB header:transferase
Chain: A: PDB Molecule:nitrate/nitrite sensor protein narq;
PDBTitle: fragment of nitrate/nitrite sensor histidine kinase narq (wt) in2 asymmetric holo state
27c4gn0D_
not modelled 98.8 11
PDB header:signaling protein
Chain: D: PDB Molecule:hamp domain of af1503;
PDBTitle: de novo phasing of a hamp-complex using an improved arcimboldo method
28c3lnrA_
not modelled 98.4 16
PDB header:signaling protein
Chain: A: PDB Molecule:aerotaxis transducer aer2;
PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2
29c3zx6A_
not modelled 98.0 13
PDB header:signaling
Chain: A: PDB Molecule:hamp, methyl-accepting chemotaxis protein i;
PDBTitle: structure of hamp(af1503)-tsr fusion - hamp (a291v) mutant
30d2asxa1
not modelled 98.0 14
Fold:HAMP domain-like
Superfamily:HAMP domain-like
Family:HAMP domain
31c3zrwB_
not modelled 97.8 15
PDB header:signaling protein
Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz;
PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant
32c4i5sA_
not modelled 97.5 23
PDB header:transferase
Chain: A: PDB Molecule:putative histidine kinase covs; vick-like protein;
PDBTitle: structure and function of sensor histidine kinase
33c4biuB_
not modelled 96.9 23
PDB header:transferase
Chain: B: PDB Molecule:sensor protein cpxa;
PDBTitle: crystal structure of cpxahdc (orthorhombic form 1)
34c2qv6D_
not modelled 96.9 19
PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase iii;
PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions
35c4ctiA_
not modelled 96.8 14
PDB header:signaling protein
Chain: A: PDB Molecule:osmolarity sensor protein envz, af1503;
PDBTitle: escherichia coli envz histidine kinase catalytic part fused to2 archaeoglobus fulgidus af1503 hamp domain
36c5llxB_
not modelled 96.0 17
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase (ggdef) domain-containing protein;
PDBTitle: bacteriophytochrome activated diguanylyl cyclase from idiomarina2 species a28l with gtp bound
37c3i5cA_
not modelled 95.5 13
PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa
38c1w25B_
not modelled 94.5 15
PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
39c2rm8A_
not modelled 94.3 20
PDB header:signaling protein
Chain: A: PDB Molecule:sensory rhodopsin ii transducer;
PDBTitle: the solution structure of phototactic transducer protein2 htrii linker region from natronomonas pharaonis
40c3breA_
not modelled 94.2 13
PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
41c4zmuD_
not modelled 93.8 12
PDB header:lyase
Chain: D: PDB Molecule:diguanylate cyclase;
PDBTitle: dcsbis, a diguanylate cyclase from pseudomonas aeruginosa
42c3ungC_
not modelled 93.7 24
PDB header:unknown function
Chain: C: PDB Molecule:cmr2dhd;
PDBTitle: structure of the cmr2 subunit of the crispr rna silencing complex
43c4wxoA_
not modelled 93.3 11
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: sadc (300-487) from pseudomonas aeruginosa pao1
44c3i5aA_
not modelled 93.3 15
PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
45c6d9mA_
not modelled 92.8 17
PDB header:hydrolase
Chain: A: PDB Molecule:fusion protein of endolysin,response receiver sensor
PDBTitle: t4-lysozyme fusion to geobacter ggdef
46c3mtkA_
not modelled 92.7 11
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c
47c3ezuA_
not modelled 92.0 20
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution
48c4w8yA_
not modelled 91.6 22
PDB header:rna binding protein
Chain: A: PDB Molecule:crispr system cmr subunit cmr2;
PDBTitle: structure of full length cmr2 from pyrococcus furiosus (manganese2 bound form)
49c5euhA_
not modelled 88.7 11
PDB header:membrane protein
Chain: A: PDB Molecule:putative ggdef domain membrane protein;
PDBTitle: crystal structure of the c-di-gmp-bound ggdef domain of p. fluorescens2 gcbc
50c3hvwA_
not modelled 88.0 13
PDB header:lyase
Chain: A: PDB Molecule:diguanylate-cyclase (dgc);
PDBTitle: crystal structure of the ggdef domain of the pa2567 protein from2 pseudomonas aeruginosa, northeast structural genomics consortium3 target par365c
51c3ignA_
not modelled 87.9 10
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of the ggdef domain from marinobacter aquaeolei2 diguanylate cyclase complexed with c-di-gmp - northeast structural3 genomics consortium target mqr89a
52d1w25a3
not modelled 84.9 13
Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:GGDEF domain
53c4zvhB_
not modelled 84.5 19
PDB header:signaling protein
Chain: B: PDB Molecule:diguanylate cyclase dosc;
PDBTitle: crystal structure of ggdef domain of the e. coli dosc - form iv
54c3i5bA_
not modelled 84.4 12
PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa
55c5m3cB_
not modelled 84.2 20
PDB header:hydrolase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: structure of the hybrid domain (ggdef-eal) of pa0575 from pseudomonas2 aeruginosa pao1 at 2.8 ang. with gtp and ca2+ bound to the active3 site of the ggdef domain
56c4h54B_
not modelled 83.2 14
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase ydeh;
PDBTitle: crystal structure of the diguanylate cyclase dgcz
57c3hvaA_
not modelled 82.7 13
PDB header:transferase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx ggdef domain from pseudomonas aeruginosa
58c3iclA_
not modelled 81.9 14
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium target mcr174c
59c4ymeA_
not modelled 81.8 16
PDB header:lyase
Chain: A: PDB Molecule:sensory box/ggdef family protein;
PDBTitle: crystal structure of a sensory box/ggdef family protein (cc_0091) from2 caulobacter crescentus cb15 at 1.40 a resolution (psi community3 target, shapiro)
60c3pjwA_
not modelled 79.4 10
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
61c4dmzB_
not modelled 78.6 6
PDB header:nucleotide-binding protein
Chain: B: PDB Molecule:putative uncharacterized protein peld;
PDBTitle: peld 156-455 from pseudomonas aeruginosa pa14, apo form
62c4urgB_
not modelled 77.6 20
PDB header:lyase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of ggdef domain from t.maritima (active-like dimer)
63c6eibC_
not modelled 76.9 12
PDB header:transferase
Chain: C: PDB Molecule:sensory box/ggdef family protein;
PDBTitle: structure of the active ggeef domain of a diguanylate cyclase from2 vibrio cholerae.
64c3qyyB_
not modelled 76.1 15
PDB header:signaling protein/inhibitor
Chain: B: PDB Molecule:response regulator;
PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp
65c4iobA_
not modelled 75.9 17
PDB header:lyase
Chain: A: PDB Molecule:diguanylate cyclase tpbb;
PDBTitle: crystal structure of the ggdef domain of pa1120 (yfin or tpbb) from2 pseudomonas aeruginosa at 2.7 ang.
66c5xgdA_
not modelled 74.7 16
PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein pa0861;
PDBTitle: crystal structure of the pas-ggdef-eal domain of pa0861 from2 pseudomonas aeruginosa in complex with gtp
67c4zmmB_
not modelled 65.1 13
PDB header:transferase
Chain: B: PDB Molecule:diguanylate cyclase;
PDBTitle: ggdef domain of dcsbis complexed with c-di-gmp
68c4euvA_
not modelled 62.8 11
PDB header:signaling protein
Chain: A: PDB Molecule:peld;
PDBTitle: crystal structure of peld 158-ct from pseudomonas aeruginosa pao1, in2 complex with c-di-gmp, form 1
69c3tvkA_
not modelled 62.7 15
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase dgcz;
PDBTitle: diguanylate cyclase domain of dgcz
70c6ifnA_
not modelled 44.5 17
PDB header:rna binding protein
Chain: A: PDB Molecule:type iii-a crispr-associated protein csm1;
PDBTitle: crystal structure of type iii-a crispr csm complex
71c3dcaC_
not modelled 40.5 11
PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:rpa0582;
PDBTitle: crystal structure of the rpa0582- protein of unknown2 function from rhodopseudomonas palustris- a structural3 genomics target
72c2w6bA_
not modelled 37.4 22
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the trimeric beta-pix coiled-coil2 domain
73c4biyD_
not modelled 36.6 19
PDB header:transferase
Chain: D: PDB Molecule:sensor protein cpxa;
PDBTitle: crystal structure of cpxahdc (monoclinic form 2)
74c3hlsE_
not modelled 36.3 18
PDB header:signaling protein
Chain: E: PDB Molecule:guanylate cyclase soluble subunit beta-1;
PDBTitle: crystal structure of the signaling helix coiled-coil doimain2 of the beta-1 subunit of the soluble guanylyl cyclase
75c4rnhA_
not modelled 34.3 21
PDB header:transferase, hydrolase
Chain: A: PDB Molecule:motility regulator;
PDBTitle: pamora tandem diguanylate cyclase - phosphodiesterase, c-di-gmp2 complex
76c2x5eA_
not modelled 33.5 10
PDB header:unknown function
Chain: A: PDB Molecule:upf0271 protein pa4511;
PDBTitle: crystal structure of the hypothetical protein pa4511 from2 pseudomonas aeruginosa
77d2dfaa1
not modelled 32.0 15
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
78c5n9jB_
not modelled 30.8 10
PDB header:transcription
Chain: B: PDB Molecule:mediator of rna polymerase ii transcription subunit 10;
PDBTitle: core mediator of transcriptional regulation
79c5buzC_
not modelled 30.6 23
PDB header:transport protein
Chain: C: PDB Molecule:snap receptor-like protein;
PDBTitle: crystal structure of a complex between the snare vam3 and the hops2 vps33-vps16 subcomplex from chaetomium thermophilum
80d1v6ta_
not modelled 29.0 7
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
81c4rndC_
not modelled 23.2 18
PDB header:hydrolase
Chain: C: PDB Molecule:v-type proton atpase subunit d;
PDBTitle: crystal structure of the subunit df-assembly of the eukaryotic v-2 atpase.
82c3w3aO_
not modelled 23.1 12
PDB header:hydrolase
Chain: O: PDB Molecule:v-type atp synthase subunit d;
PDBTitle: crystal structure of v1-atpase at 3.9 angstrom resolution
83c5bw9G_
not modelled 20.6 14
PDB header:hydrolase
Chain: G: PDB Molecule:v-type proton atpase subunit d;
PDBTitle: crystal structure of yeast v1-atpase in the autoinhibited form
84c6b87C_
not modelled 15.8 25
PDB header:membrane protein
Chain: C: PDB Molecule:tmhc2_e;
PDBTitle: crystal structure of transmembrane protein tmhc2_e
85d1h41a2
not modelled 15.5 16
Fold:Zincin-like
Superfamily:beta-N-acetylhexosaminidase-like domain
Family:alpha-D-glucuronidase, N-terminal domain
86c6iu3A_
not modelled 15.1 21
PDB header:metal transport
Chain: A: PDB Molecule:vit1;
PDBTitle: crystal structure of iron transporter vit1 with zinc ions
87c3a5dG_
not modelled 14.9 12
PDB header:hydrolase
Chain: G: PDB Molecule:v-type atp synthase subunit d;
PDBTitle: inter-subunit interaction and quaternary rearrangement2 defined by the central stalk of prokaryotic v1-atpase
88c4axkB_
not modelled 14.4 29
PDB header:isomerase
Chain: B: PDB Molecule:1-(5-phosphoribosyl)-5-((5'-phosphoribosylamino)
PDBTitle: crystal structure of subhisa from the thermophile corynebacterium2 efficiens
89c3j9vM_
not modelled 13.2 18
PDB header:hydrolase
Chain: M: PDB Molecule:v-type proton atpase subunit d;
PDBTitle: yeast v-atpase state 3
90c3nvbA_
not modelled 12.7 14
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of n-terminal part of the protein bf1531 from2 bacteroides fragilis containing phosphatase domain complexed with mg3 and tungstate
91d1veha_
not modelled 12.2 15
Fold:Alpha-lytic protease prodomain-like
Superfamily:Fe-S cluster assembly (FSCA) domain-like
Family:NifU C-terminal domain-like
92c6iqwA_
not modelled 11.6 17
PDB header:rna binding protein/rna
Chain: A: PDB Molecule:csm1;
PDBTitle: cryo-em structure of csm effector complex
93c5xu1M_
not modelled 11.3 11
PDB header:transport protein
Chain: M: PDB Molecule:abc transporter permeae;
PDBTitle: structure of a non-canonical abc transporter from streptococcus2 pneumoniae r6
94d2hwna1
not modelled 10.7 23
Fold:Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
Superfamily:Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
Family:Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit
95c3lmbA_
not modelled 10.5 18
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein olei01261 with unknown function2 from chlorobaculum tepidum tls
96c2f7tA_
not modelled 10.5 6
PDB header:dna binding protein
Chain: A: PDB Molecule:mos1 transposase;
PDBTitle: crystal structure of the catalytic domain of mos1 mariner2 transposase
97c5cw9A_
not modelled 10.5 24
PDB header:de novo protein
Chain: A: PDB Molecule:de novo designed ferredoxin-ferredoxin domain insertion
PDBTitle: crystal structure of de novo designed ferredoxin-ferredoxin domain2 insertion protein
98c2kjwA_
not modelled 10.4 17
PDB header:ribosomal protein
Chain: A: PDB Molecule:30s ribosomal protein s6;
PDBTitle: solution structure and backbone dynamics of the permutant p54-55
99d1q8ka2
not modelled 10.0 13
Fold:Ferredoxin-like
Superfamily:eIF-2-alpha, C-terminal domain
Family:eIF-2-alpha, C-terminal domain

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Transmembrane helix prediction 

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