1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	A	L	V	T	K	L	L	V	A	S	R	N	R	K	K	L	A	E	L	R	R	V	L	D	G	A	G	L	S	G	L	T	L	L	S	L	G	D	V	S	P	L	P	E	T	P	E	T	G	V	T	F	E	D	N	A	L	A	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	R	D	A	F	S	A	T	G	L	A	S	V	A	D	D	S	G	L	E	V	A	A	L	G	G	M	P	G	V	L	S	A	R	W	S	G	R	Y	G	D	D	A	A	N	T	A	L	L	L	A	Q	L	C	D	V	P	D	E	R
Secondary structure
SS confidence
Disorder																																										?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	G	A	A	F	V	S	A	C	A	L	V	S	G	S	G	E	V	V	V	R	G	E	W	P	G	T	I	A	R	E	P	R	G	D	G	G	F	G	Y	D	P	V	F	V	P	Y	G	D	D	R	T	A	A	Q	L	S	P	A	E
Secondary structure
SS confidence
Disorder																																	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.
Sequence		K	D	A	V	S	H	R	G	R	A	L	A	L	L	L	P	A	L	R	S	L	A	T	G
Secondary structure
SS confidence
Disorder																								?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 8%) Alpha helix ( 34%) Beta strand ( 27%)

Rank Aligned region

PDB 3tqu chain D Region: 4 - 200 Aligned: 193 Modelled: 196 Confidence: 100.0% Identity: 43% PDB header:hydrolase Chain: D: PDB Molecule:non-canonical purine ntp pyrophosphatase; PDBTitle: structure of a ham1 protein from coxiella burnetii Phyre2 PDB 1k7k chain A Region: 4 - 200 Aligned: 193 Modelled: 196 Confidence: 100.0% Identity: 46% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 4bnq chain A Region: 5 - 202 Aligned: 191 Modelled: 198 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:non-canonical purine ntp pyrophosphatase; PDBTitle: the structure of the staphylococcus aureus ham1 protein Phyre2 PDB 1vp2 chain A Region: 5 - 201 Aligned: 185 Modelled: 194 Confidence: 100.0% Identity: 34% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 2car chain A domain 1 Region: 3 - 203 Aligned: 186 Modelled: 201 Confidence: 100.0% Identity: 31% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 1v7r chain A Region: 5 - 201 Aligned: 183 Modelled: 197 Confidence: 100.0% Identity: 29% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 1b78 chain A Region: 6 - 200 Aligned: 181 Modelled: 195 Confidence: 100.0% Identity: 28% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: ITPase (Ham1) Phyre2 PDB 4oo0 chain B Region: 3 - 152 Aligned: 122 Modelled: 150 Confidence: 96.9% Identity: 28% PDB header:hydrolase Chain: B: PDB Molecule:maf-like protein bcal2394; PDBTitle: crystal structure of maf-like protein bcej2315_23540 from burkholderia2 cenocepacia Phyre2 PDB 2amh chain A domain 1 Region: 4 - 148 Aligned: 121 Modelled: 145 Confidence: 96.2% Identity: 16% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: Maf-like Phyre2 PDB 1ex2 chain A Region: 3 - 145 Aligned: 121 Modelled: 143 Confidence: 95.4% Identity: 17% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: Maf-like Phyre2 PDB 4jhc chain A Region: 6 - 152 Aligned: 119 Modelled: 147 Confidence: 92.1% Identity: 21% PDB header:cell cycle Chain: A: PDB Molecule:maf-like protein ycef; PDBTitle: crystal structure of the uncharacterized maf protein ycef from e. coli Phyre2 PDB 4heb chain A Region: 5 - 145 Aligned: 119 Modelled: 140 Confidence: 91.8% Identity: 18% PDB header:cell cycle Chain: A: PDB Molecule:septum formation protein maf; PDBTitle: the crystal structure of maf protein of bacillus subtilis Phyre2 PDB 6mu0 chain A Region: 3 - 93 Aligned: 83 Modelled: 82 Confidence: 90.1% Identity: 22% PDB header:isomerase Chain: A: PDB Molecule:probable ribose-5-phosphate isomerase b; PDBTitle: crystal structure of ribose-5-phosphate isomerase b from mycoplasma2 genitalium with bound ribulose-5-phosphate Phyre2 PDB 2p5x chain B Region: 3 - 152 Aligned: 130 Modelled: 150 Confidence: 86.0% Identity: 19% PDB header:cell cycle Chain: B: PDB Molecule:n-acetylserotonin o-methyltransferase-like protein; PDBTitle: crystal structure of maf domain of human n-acetylserotonin o-2 methyltransferase-like protein Phyre2 PDB 1u5w chain A domain 1 Region: 4 - 70 Aligned: 67 Modelled: 67 Confidence: 85.4% Identity: 15% Fold: Anticodon-binding domain-like Superfamily: ITPase-like Family: YjjX-like Phyre2 PDB 4p0e chain B Region: 7 - 145 Aligned: 117 Modelled: 139 Confidence: 84.3% Identity: 19% PDB header:unknown function Chain: B: PDB Molecule:maf-like protein yhde; PDBTitle: yhde e33a (p212121 space group) Phyre2 PDB 4em8 chain A Region: 3 - 93 Aligned: 82 Modelled: 83 Confidence: 83.4% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase b; PDBTitle: the structure of ribose 5-phosphate isomerase b from anaplasma2 phagocytophilum Phyre2 PDB 5d5p chain C Region: 6 - 74 Aligned: 61 Modelled: 69 Confidence: 78.6% Identity: 16% PDB header:transferase Chain: C: PDB Molecule:hcgb; PDBTitle: hcgb from methanococcus maripaludis Phyre2 PDB 6fxs chain A Region: 3 - 93 Aligned: 84 Modelled: 84 Confidence: 77.8% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase, putative; PDBTitle: structure of trypanosoma brucei type b ribose 5-phosphate isomerase Phyre2 PDB 6fxw chain A Region: 3 - 93 Aligned: 84 Modelled: 91 Confidence: 76.7% Identity: 13% PDB header:isomerase Chain: A: PDB Molecule:putative ribose 5-phosphate isomerase; PDBTitle: structure of leishmania infantum type b ribose 5-phosphate isomerase Phyre2 1 c3tquD_ 2 d1k7ka_ 3 c4bnqA_ 4 d1vp2a_ 5 d2cara1 6 d1v7ra_ 7 d1b78a_ 8 c4oo0B_ 9 d2amha1 10 d1ex2a_ 11 c4jhcA_ 12 c4hebA_ 13 c6mu0A_ 14 c2p5xB_ 15 d1u5wa1 16 c4p0eB_ 17 c4em8A_ 18 c5d5pC_ 19 c6fxsA_ 20 c6fxwA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99