1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	P	R	S	L	P	R	Y	G	N	S	S	R	R	K	S	F	P	M	H	R	P	S	N	V	A	T	A	T	R	K	K	S	S	I	G	W	V	L	L	A	C	S	V	A	G	C	K	G	I	D	T	T	E	F	I	L	G	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?			?		?	?	?										?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
Sequence		A	G	A	F	E	L	A	V	R	A	A	Q	H	R	H	R	Y	L	T	M	V	N	V	G	R	A	P	P	R	R	C	R	T	V	C	M	A	A	T	D	T	P	R	N	I	R	L	N	G
Secondary structure
SS confidence
Disorder																										?	?														?		?	?	?	?		?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 28%) Alpha helix ( 12%) Beta strand ( 38%)

Rank Aligned region

PDB 1q32 chain A domain 2 Region: 11 - 41 Aligned: 31 Modelled: 31 Confidence: 22.6% Identity: 26% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 3lhn chain B Region: 46 - 66 Aligned: 20 Modelled: 21 Confidence: 11.0% Identity: 50% PDB header:lipid binding protein Chain: B: PDB Molecule:lipoprotein; PDBTitle: crystal structure of putative lipoprotein (np_718719.1) from2 shewanella oneidensis at 1.42 a resolution Phyre2 PDB 2eln chain A Region: 39 - 49 Aligned: 11 Modelled: 11 Confidence: 9.6% Identity: 45% PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 406; PDBTitle: solution structure of the 11th c2h2 zinc finger of human2 zinc finger protein 406 Phyre2 PDB 3sq3 chain C Region: 11 - 41 Aligned: 31 Modelled: 31 Confidence: 7.9% Identity: 26% PDB header:hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna phosphodiesterase2 h182a mutant Phyre2 PDB 4cmq chain B Region: 34 - 74 Aligned: 41 Modelled: 41 Confidence: 7.5% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:crispr-associated endonuclease cas9/csn1; PDBTitle: crystal structure of mn-bound s.pyogenes cas9 Phyre2 PDB 2mf8 chain A Region: 40 - 51 Aligned: 12 Modelled: 12 Confidence: 7.1% Identity: 50% PDB header:metal binding protein/dna Chain: A: PDB Molecule:myelin transcription factor 1; PDBTitle: haddock model of myt1 f4f5 - dna complex Phyre2 PDB 5wwp chain A Region: 8 - 59 Aligned: 52 Modelled: 52 Confidence: 6.9% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:orf1ab; PDBTitle: crystal structure of middle east respiratory syndrome coronavirus2 helicase (mers-cov nsp13) Phyre2 PDB 5vob chain C Region: 52 - 65 Aligned: 14 Modelled: 14 Confidence: 6.6% Identity: 36% PDB header:viral protein/immune system Chain: C: PDB Molecule:envelope glycoprotein ul128; PDBTitle: crystal structure of hcmv pentamer in complex with neutralizing2 antibody 8i21 Phyre2 PDB 5cff chain E Region: 77 - 91 Aligned: 15 Modelled: 15 Confidence: 6.1% Identity: 40% PDB header:transcription/rna binding protein Chain: E: PDB Molecule:staufen; PDBTitle: crystal structure of miranda/staufen dsrbd5 complex Phyre2 PDB 1ebf chain A domain 2 Region: 53 - 72 Aligned: 20 Modelled: 20 Confidence: 6.0% Identity: 30% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Homoserine dehydrogenase-like Phyre2 PDB 2y8s chain E Region: 80 - 93 Aligned: 14 Modelled: 14 Confidence: 5.8% Identity: 50% PDB header:membrane protein Chain: E: PDB Molecule:rhoptry neck protein 2; PDBTitle: co-structure of an ama1 mutant (y230a) with a surface exposed region2 of ron2 from toxoplasma gondii Phyre2 PDB 2z4h chain B Region: 46 - 66 Aligned: 20 Modelled: 21 Confidence: 5.7% Identity: 35% PDB header:signaling protein activator Chain: B: PDB Molecule:copper homeostasis protein cutf; PDBTitle: crystal structure of the cpx pathway activator nlpe from2 escherichia coli Phyre2 PDB 4i21 chain C Region: 3 - 11 Aligned: 9 Modelled: 9 Confidence: 5.7% Identity: 67% PDB header:transferase/transferase inhibitor Chain: C: PDB Molecule:erbb receptor feedback inhibitor 1; PDBTitle: crystal structure of l858r + t790m egfr kinase domain in complex with2 mig6 peptide Phyre2 PDB 2y8t chain B Region: 80 - 93 Aligned: 14 Modelled: 14 Confidence: 5.7% Identity: 50% PDB header:membrane protein Chain: B: PDB Molecule:rhoptry neck protein 2; PDBTitle: co-structure of ama1 with a surface exposed region of ron2 from2 toxoplasma gondii Phyre2 PDB 3do5 chain A Region: 53 - 72 Aligned: 20 Modelled: 20 Confidence: 5.5% Identity: 35% PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: crystal structure of putative homoserine dehydrogenase (np_069768.1)2 from archaeoglobus fulgidus at 2.20 a resolution Phyre2 PDB 4fwv chain A Region: 49 - 67 Aligned: 19 Modelled: 19 Confidence: 5.5% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:ttc1975 peptidase; PDBTitle: crystal structure of the n-terminal domain of the lon-like protease2 mtalonc Phyre2 PDB 1bnd chain B Region: 44 - 53 Aligned: 10 Modelled: 10 Confidence: 5.5% Identity: 50% Fold: Cystine-knot cytokines Superfamily: Cystine-knot cytokines Family: Neurotrophin Phyre2 PDB 2d8x chain A domain 2 Region: 55 - 60 Aligned: 6 Modelled: 6 Confidence: 5.2% Identity: 83% Fold: Glucocorticoid receptor-like (DNA-binding domain) Superfamily: Glucocorticoid receptor-like (DNA-binding domain) Family: LIM domain Phyre2 1 d1q32a2 2 c3lhnB_ 3 c2elnA_ 4 c3sq3C_ 5 c4cmqB_ 6 c2mf8A_ 7 c5wwpA_ 8 c5vobC_ 9 c5cffE_ 10 d1ebfa2 11 c2y8sE_ 12 c2z4hB_ 13 c4i21C_ 14 c2y8tB_ 15 c3do5A_ 16 c4fwvA_ 17 d1bndb_ 18 d2d8xa2