1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	P	S	R	Q	G	E	V	G	E	V	A	G	Y	V	V	E	Y	N	R	R	T	H	V	R	R	I	T	E	F	A	T	P	Q	E	A	M	E	H	R	L	K	L	E	A	E	R	T	D	S	N	I	E	I	V	A	L	V	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																								?													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.
Sequence		K	S	L	G	T	L	K	Q	T	H	S	R	Y	F	T	G	E	E	L	N	V	G	N	G	A	R
Secondary structure
SS confidence
Disorder		?	?																		?	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 27%) Alpha helix ( 34%) Beta strand ( 22%)

Rank Aligned region

PDB 1i32 chain D Region: 40 - 73 Aligned: 34 Modelled: 34 Confidence: 53.9% Identity: 24% PDB header:oxidoreductase Chain: D: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase; PDBTitle: leishmania mexicana glyceraldehyde-3-phosphate2 dehydrogenase in complex with inhibitors Phyre2 PDB 5zoj chain E Region: 7 - 81 Aligned: 49 Modelled: 50 Confidence: 37.5% Identity: 27% PDB header:dna binding protein Chain: E: PDB Molecule:inner nuclear membrane protein man1; PDBTitle: crystal structure of human smad2-man1 complex Phyre2 PDB 3s6e chain B Region: 7 - 81 Aligned: 49 Modelled: 46 Confidence: 37.1% Identity: 27% PDB header:rna binding protein Chain: B: PDB Molecule:rna-binding protein 39; PDBTitle: crystal structure of a rna binding motif protein 39 (rbm39) from mus2 musculus at 0.95 a resolution Phyre2 PDB 1k3t chain A domain 1 Region: 40 - 66 Aligned: 27 Modelled: 27 Confidence: 30.0% Identity: 19% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1i32 chain A domain 1 Region: 40 - 66 Aligned: 27 Modelled: 27 Confidence: 29.3% Identity: 15% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 2b4r chain O domain 1 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 23.4% Identity: 33% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3dlb chain A Region: 10 - 84 Aligned: 57 Modelled: 67 Confidence: 22.3% Identity: 25% PDB header:nucleic acid binding protein/dna Chain: A: PDB Molecule:argonaute; PDBTitle: crystal structure of the guide-strand-containing argonaute2 protein silencing complex Phyre2 PDB 1gga chain A domain 1 Region: 40 - 66 Aligned: 27 Modelled: 27 Confidence: 19.4% Identity: 15% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1azp chain A Region: 9 - 49 Aligned: 41 Modelled: 41 Confidence: 17.2% Identity: 22% Fold: SH3-like barrel Superfamily: Chromo domain-like Family: "Histone-like" proteins from archaea Phyre2 PDB 3ho1 chain A Region: 10 - 74 Aligned: 48 Modelled: 65 Confidence: 17.0% Identity: 27% PDB header:nucleic acid binding protein/dna/rna Chain: A: PDB Molecule:argonaute; PDBTitle: crystal structure of t. thermophilus argonaute n546 mutant protein2 complexed with dna guide strand and 12-nt rna target strand Phyre2 PDB 3aqj chain Q Region: 16 - 29 Aligned: 14 Modelled: 14 Confidence: 14.6% Identity: 29% PDB header:metal binding protein Chain: Q: PDB Molecule:baseplate assembly protein v; PDBTitle: crystal structure of a c-terminal domain of the bacteriophage p2 tail2 spike protein, gpv Phyre2 PDB 4yh8 chain A Region: 10 - 81 Aligned: 46 Modelled: 47 Confidence: 13.7% Identity: 30% PDB header:splicing Chain: A: PDB Molecule:splicing factor u2af 23 kda subunit; PDBTitle: structure of yeast u2af complex Phyre2 PDB 1u8f chain O domain 1 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 12.9% Identity: 27% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1j0x chain O domain 1 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 12.6% Identity: 27% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3cie chain C Region: 41 - 75 Aligned: 35 Modelled: 35 Confidence: 12.0% Identity: 26% PDB header:oxidoreductase Chain: C: PDB Molecule:glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of glyceraldehyde 3-phosphate2 dehydrogenase from cryptosporidium parvum Phyre2 PDB 1od6 chain A Region: 38 - 74 Aligned: 37 Modelled: 37 Confidence: 9.8% Identity: 19% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 3gpd chain G domain 1 Region: 41 - 73 Aligned: 33 Modelled: 33 Confidence: 9.8% Identity: 27% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1o0p chain A Region: 66 - 81 Aligned: 16 Modelled: 16 Confidence: 9.0% Identity: 13% Fold: Ferredoxin-like Superfamily: RNA-binding domain, RBD Family: Canonical RBD Phyre2 PDB 4k29 chain A Region: 16 - 80 Aligned: 51 Modelled: 57 Confidence: 8.8% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:enoyl-coa hydratase/isomerase; PDBTitle: crystal structure of an enoyl-coa hydratase/isomerase from2 xanthobacter autotrophicus py2 Phyre2 PDB 1yvu chain A domain 2 Region: 10 - 83 Aligned: 57 Modelled: 74 Confidence: 8.7% Identity: 19% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: PIWI domain Phyre2 1 c1i32D_ 2 c5zojE_ 3 c3s6eB_ 4 d1k3ta1 5 d1i32a1 6 d2b4ro1 7 c3dlbA_ 8 d1ggaa1 9 d1azpa_ 10 c3ho1A_ 11 c3aqjQ_ 12 c4yh8A_ 13 d1u8fo1 14 d1j0xo1 15 c3cieC_ 16 d1od6a_ 17 d3gpdg1 18 d1o0pa_ 19 c4k29A_ 20 d1yvua2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38