1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		V	S	I	S	Q	S	D	A	S	L	A	A	V	P	A	V	D	Q	F	D	P	S	S	G	A	S	G	G	Y	D	T	P	L	G	I	T	N	P	P	I	D	E	L	L	D	R	V	S	S	K	Y	A	L	V	I	Y	A	A	K	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
Sequence		A	R	Q	I	N	D	Y	Y	N	Q	L	G	E	G	I	L	E	Y	V	G	P	L	V	E	P	G	L	Q	E	K	P	L	S	I	A	L	R	E	I	H	A	D	L	L	E	H	T	E	G	E
Secondary structure
SS confidence
Disorder									?		?	?	?	?	?	?	?	?											?																	?	?	?	?	?	?
Disorder confidence

Confidence Key High(9)                     Low (0)

? Disordered ( 33%) Alpha helix ( 50%) Beta strand ( 0%)

Rank Aligned region

PDB 5tw1 chain E Region: 29 - 109 Aligned: 74 Modelled: 81 Confidence: 100.0% Identity: 96% PDB header:transcription activator/transferase/dna Chain: E: PDB Molecule:dna-directed rna polymerase subunit omega; PDBTitle: crystal structure of a mycobacterium smegmatis transcription2 initiation complex with rbpa Phyre2 PDB 6asx chain K Region: 37 - 106 Aligned: 59 Modelled: 70 Confidence: 99.9% Identity: 29% PDB header:transcription/dna/rna Chain: K: PDB Molecule:dna-directed rna polymerase subunit omega; PDBTitle: cryoem structure of e.coli his pause elongation complex Phyre2 PDB 3iyd chain E Region: 40 - 110 Aligned: 60 Modelled: 71 Confidence: 99.8% Identity: 28% PDB header:transcription/dna Chain: E: PDB Molecule:dna-directed rna polymerase subunit omega; PDBTitle: three-dimensional em structure of an intact activator-dependent2 transcription initiation complex Phyre2 PDB 6j9e chain E Region: 40 - 106 Aligned: 51 Modelled: 67 Confidence: 99.8% Identity: 41% PDB header:transcription Chain: E: PDB Molecule:dna-directed rna polymerase subunit omega; PDBTitle: cryo-em structure of xanthomonos oryzae transcription elongation2 complex with nusa and the bacteriophage protein p7 Phyre2 PDB 1ynj chain K domain 1 Region: 35 - 109 Aligned: 69 Modelled: 75 Confidence: 98.7% Identity: 30% Fold: RPB6/omega subunit-like Superfamily: RPB6/omega subunit-like Family: RNA polymerase omega subunit Phyre2 PDB 1smy chain E Region: 38 - 109 Aligned: 66 Modelled: 72 Confidence: 98.7% Identity: 33% Fold: RPB6/omega subunit-like Superfamily: RPB6/omega subunit-like Family: RNA polymerase omega subunit Phyre2 PDB 1twf chain F Region: 49 - 104 Aligned: 45 Modelled: 56 Confidence: 96.9% Identity: 27% Fold: RPB6/omega subunit-like Superfamily: RPB6/omega subunit-like Family: RPB6 Phyre2 PDB 1twc chain F Region: 49 - 104 Aligned: 45 Modelled: 56 Confidence: 96.9% Identity: 27% PDB header:transcription Chain: F: PDB Molecule:dna-directed rna polymerases i, ii, and iii 23 PDBTitle: rna polymerase ii complexed with gtp Phyre2 PDB 4qiw chain T Region: 49 - 104 Aligned: 45 Modelled: 56 Confidence: 96.9% Identity: 22% PDB header:transcription Chain: T: PDB Molecule:dna-directed rna polymerase subunit k; PDBTitle: crystal structure of euryarchaeal rna polymerase from thermococcus2 kodakarensis Phyre2 PDB 1qkl chain A Region: 49 - 104 Aligned: 45 Modelled: 56 Confidence: 96.8% Identity: 31% Fold: RPB6/omega subunit-like Superfamily: RPB6/omega subunit-like Family: RPB6 Phyre2 PDB 3h0g chain F Region: 49 - 104 Aligned: 45 Modelled: 56 Confidence: 96.7% Identity: 29% PDB header:transcription Chain: F: PDB Molecule:dna-directed rna polymerases i, ii, and iii subunit rpabc2; PDBTitle: rna polymerase ii from schizosaccharomyces pombe Phyre2 PDB 2pmz chain W Region: 49 - 104 Aligned: 45 Modelled: 56 Confidence: 96.3% Identity: 24% PDB header:translation, transferase Chain: W: PDB Molecule:dna-directed rna polymerase subunit k; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus Phyre2 PDB 2kxh chain B Region: 57 - 66 Aligned: 10 Modelled: 10 Confidence: 14.6% Identity: 60% PDB header:protein binding Chain: B: PDB Molecule:peptide of far upstream element-binding protein 1; PDBTitle: solution structure of the first two rrm domains of fir in the complex2 with fbp nbox peptide Phyre2 PDB 6d6r chain L Region: 37 - 49 Aligned: 13 Modelled: 13 Confidence: 14.4% Identity: 23% PDB header:hydrolase Chain: L: PDB Molecule:m-phase phosphoprotein 6; PDBTitle: human nuclear exosome-mtr4 rna complex - composite map after focused2 reconstruction Phyre2 PDB 6d6q chain L Region: 37 - 49 Aligned: 13 Modelled: 13 Confidence: 14.4% Identity: 23% PDB header:hydrolase Chain: L: PDB Molecule:m-phase phosphoprotein 6; PDBTitle: human nuclear exosome-mtr4 rna complex - overall reconstruction Phyre2 PDB 6c05 chain F Region: 6 - 75 Aligned: 68 Modelled: 70 Confidence: 10.1% Identity: 15% PDB header:transcription Chain: F: PDB Molecule:rna polymerase sigma factor siga; PDBTitle: mycobacterium tuberculosis rnap holo/rbpa in relaxed state Phyre2 PDB 1gzs chain B Region: 36 - 97 Aligned: 59 Modelled: 62 Confidence: 9.3% Identity: 24% Fold: SopE-like GEF domain Superfamily: SopE-like GEF domain Family: SopE-like GEF domain Phyre2 PDB 1tjl chain D Region: 4 - 24 Aligned: 21 Modelled: 21 Confidence: 9.2% Identity: 24% PDB header:transcription Chain: D: PDB Molecule:dnak suppressor protein; PDBTitle: crystal structure of transcription factor dksa from e. coli Phyre2 PDB 6hlw chain B Region: 38 - 49 Aligned: 12 Modelled: 12 Confidence: 8.7% Identity: 42% PDB header:viral protein Chain: B: PDB Molecule:genome polyprotein; PDBTitle: crystal structure of human acbd3 gold domain in complex with 3a2 protein of enterovirus-a71 (fusion protein) Phyre2 PDB 3m1r chain F Region: 16 - 69 Aligned: 54 Modelled: 50 Confidence: 8.6% Identity: 20% PDB header:hydrolase Chain: F: PDB Molecule:formimidoylglutamase; PDBTitle: the crystal structure of formimidoylglutamase from bacillus2 subtilis subsp. subtilis str. 168 Phyre2 1 c5tw1E_ 2 c6asxK_ 3 c3iydE_ 4 c6j9eE_ 5 d1ynjk1 6 d1smye_ 7 d1twff_ 8 c1twcF_ 9 c4qiwT_ 10 d1qkla_ 11 c3h0gF_ 12 c2pmzW_ 13 c2kxhB_ 14 c6d6rL_ 15 c6d6qL_ 16 c6c05F_ 17 d1gzsb_ 18 c1tjlD_ 19 c6hlwB_ 20 c3m1rF_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39